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Murcko scaffold

Thiazole, 4-phenyl- scaffold

2,769 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
2,769
With full pages
400
Scaffold SMILES

c1ccc(-c2cscn2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Thiazole, 4-phenyl- page
Murcko scaffold c1ccc(-c2cscn2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 2,769 chemicals

2-Amino-4-(p-nitrophenyl)thiazole chemical structure, C9H7N3O2S, CAS 2104-09-8
2-Amino-4-(p-nitrophenyl)thiazole
CAS 2104-09-8C9H7N3O2S
2-Amino-4-phenylthiazole chemical structure, C9H8N2S, CAS 2010-06-2
2-Amino-4-phenylthiazole
CAS 2010-06-2C9H8N2S
Lotifazole chemical structure, C12H9Cl3N2O2S, CAS 71119-10-3
Lotifazole
CAS 71119-10-3C12H9Cl3N2O2S
Tioxamast chemical structure, C14H14N2O4S, CAS 74531-88-7
Tioxamast
CAS 74531-88-7C14H14N2O4S
4-Phenyl-5-tetradecyl-2-thiazolamine chemical structure, C23H36N2S, CAS 64415-14-1
4-Phenyl-5-tetradecyl-2-thiazolamine
CAS 64415-14-1C23H36N2S
Ethyl 2-amino-4-phenyl-1,3-thiazole-5-carboxylate chemical structure, C12H12N2O2S, CAS 64399-23-1
Ethyl 2-amino-4-phenyl-1,3-thiazole-5-carboxylate
CAS 64399-23-1C12H12N2O2S
2-Amino-4-(4-chlorophenyl)thiazole chemical structure, C9H7ClN2S, CAS 2103-99-3
2-Amino-4-(4-chlorophenyl)thiazole
CAS 2103-99-3C9H7ClN2S
Thiazole, 4-phenyl- chemical structure, C9H7NS, CAS 1826-12-6
Thiazole, 4-phenyl-
CAS 1826-12-6C9H7NS
2-(Ethylthio)-4-phenylthiazole chemical structure, C11H11NS2, CAS 5316-74-5
2-(Ethylthio)-4-phenylthiazole
CAS 5316-74-5C11H11NS2
2-Hydrazino-4-(4-aminophenyl)thiazole chemical structure, C9H10N4S, CAS 26049-71-8
2-Hydrazino-4-(4-aminophenyl)thiazole
CAS 26049-71-8C9H10N4S
2-Amino-4-phenyl-5-methylthiazole chemical structure, C10H10N2S, CAS 30709-67-2
2-Amino-4-phenyl-5-methylthiazole
CAS 30709-67-2C10H10N2S
2-Hydrazinyl-4-phenylthiazole chemical structure, C9H9N3S, CAS 34176-52-8
2-Hydrazinyl-4-phenylthiazole
CAS 34176-52-8C9H9N3S
Guanidine, [4-[3-[[(methylamino)methylene]amino]phenyl]-2-thiazolyl]- chemical structure, C12H14N6S, CAS 88541-12-2
Guanidine, [4-[3-[[(methylamino)methylene]amino]phenyl]-2-thiazolyl]-
CAS 88541-12-2C12H14N6S
2-Thiazolamine, 5-ethyl-4-phenyl- chemical structure, C11H12N2S, CAS 34176-47-1
2-Thiazolamine, 5-ethyl-4-phenyl-
CAS 34176-47-1C11H12N2S
Urea, N-(4-phenyl-2-thiazolyl)-N'-2-propenyl- chemical structure, C13H13N3OS, CAS 39893-79-3
Urea, N-(4-phenyl-2-thiazolyl)-N'-2-propenyl-
CAS 39893-79-3C13H13N3OS
Urea, N,N'-dibutyl-N-(4-phenyl-2-thiazolyl)- chemical structure, C18H25N3OS, CAS 39893-94-2
Urea, N,N'-dibutyl-N-(4-phenyl-2-thiazolyl)-
CAS 39893-94-2C18H25N3OS
Urea, N-(4-(4-methoxyphenyl)-2-thiazolyl)-N'-methyl- chemical structure, C12H13N3O2S, CAS 41213-75-6
Urea, N-(4-(4-methoxyphenyl)-2-thiazolyl)-N'-methyl-
CAS 41213-75-6C12H13N3O2S
1-Methyl-3-(4-phenyl-2-thiazolyl)urea chemical structure, C11H11N3OS, CAS 52968-02-2
1-Methyl-3-(4-phenyl-2-thiazolyl)urea
CAS 52968-02-2C11H11N3OS
2-Formylamino-4-(4-nitrophenyl)thiazole chemical structure, C10H7N3O3S, CAS 64201-68-9
2-Formylamino-4-(4-nitrophenyl)thiazole
CAS 64201-68-9C10H7N3O3S
2-Methyl-4-(4-aminophenyl)thiazole chemical structure, C10H10N2S, CAS 25021-49-2
2-Methyl-4-(4-aminophenyl)thiazole
CAS 25021-49-2C10H10N2S
Acetic acid, ((4-(3-methoxyphenyl)-2-thiazolyl)amino)oxo-, ethyl ester chemical structure, C14H14N2O4S, CAS 74604-51-6
Acetic acid, ((4-(3-methoxyphenyl)-2-thiazolyl)amino)oxo-, ethyl ester
CAS 74604-51-6C14H14N2O4S
2-Amino-4-(4-methoxyphenyl)thiazole chemical structure, C10H10N2OS, CAS 2104-04-3
2-Amino-4-(4-methoxyphenyl)thiazole
CAS 2104-04-3C10H10N2OS
Propanoic acid, 2-((4-(4-chlorophenyl)-2-thiazolyl)oxy)- chemical structure, C12H10ClNO3S, CAS 42445-58-9
Propanoic acid, 2-((4-(4-chlorophenyl)-2-thiazolyl)oxy)-
CAS 42445-58-9C12H10ClNO3S
[4-(4-Chlorophenyl)-2-(diethylamino)-1,3-thiazol-5-yl]acetic acid chemical structure, C15H17ClN2O2S, CAS 49780-02-1
[4-(4-Chlorophenyl)-2-(diethylamino)-1,3-thiazol-5-yl]acetic acid
CAS 49780-02-1C15H17ClN2O2S