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Murcko scaffold

Ring system with 2 rings and 13 atoms

42 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
13
Chemicals
42
With full pages
9
Scaffold SMILES

c1ccc(CCc2ncc[nH]2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(CCc2ncc[nH]2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 42 of 42 chemicals

1-(1-Methyl-1H-imidazol-2-yl)-2-phenyl-2-propanol chemical structure, C13H16N2O, CAS 51593-81-8
1-(1-Methyl-1H-imidazol-2-yl)-2-phenyl-2-propanol
CAS 51593-81-8C13H16N2O
2-(1-Methyl-5-nitro-2-imidazolyl)-1-phenyl-1-ethanol chemical structure, C12H13N3O3, CAS 32097-42-0
2-(1-Methyl-5-nitro-2-imidazolyl)-1-phenyl-1-ethanol
CAS 32097-42-0C12H13N3O3
2-[2-(2-Bromophenyl)ethyl]-1H-imidazole chemical structure, C11H11BrN2, CAS 132666-58-1
2-[2-(2-Bromophenyl)ethyl]-1H-imidazole
CAS 132666-58-1C11H11BrN2
2-[2-(4-Bromophenyl)ethyl]-1H-imidazole chemical structure, C11H11BrN2, CAS 132666-59-2
2-[2-(4-Bromophenyl)ethyl]-1H-imidazole
CAS 132666-59-2C11H11BrN2
1-Methyl-2-(2-phenylethyl)-1H-imidazol-5-amine chemical structure, C12H15N3, CAS 145798-99-8
1-Methyl-2-(2-phenylethyl)-1H-imidazol-5-amine
CAS 145798-99-8C12H15N3
4-[2-(5-Bromo-1H-imidazol-2-yl)ethyl]phenol chemical structure, C11H11BrN2O, CAS 102151-98-4
4-[2-(5-Bromo-1H-imidazol-2-yl)ethyl]phenol
CAS 102151-98-4C11H11BrN2O
2-(1H-Imidazol-2-yl)-1-phenylethan-1-amine chemical structure, C11H13N3, CAS 923105-35-5
2-(1H-Imidazol-2-yl)-1-phenylethan-1-amine
CAS 923105-35-5C11H13N3
1-(1-Methyl-1H-imidazol-2-yl)-2-phenylethan-1-amine chemical structure, C12H15N3, CAS 927986-58-1
1-(1-Methyl-1H-imidazol-2-yl)-2-phenylethan-1-amine
CAS 927986-58-1C12H15N3
2-(1H-Imidazol-2-yl)-1-phenylethan-1-amine hydrochloride chemical structure, C11H14ClN3, CAS 1170087-60-1
2-(1H-Imidazol-2-yl)-1-phenylethan-1-amine hydrochloride
CAS 1170087-60-1C11H14ClN3
Methyl 2-(2-phenylethyl)-1H-imidazole-4-carboxylate chemical structure, C13H14N2O2, CAS 175210-31-8
Methyl 2-(2-phenylethyl)-1H-imidazole-4-carboxylate
CAS 175210-31-8C13H14N2O2
Methyl 2-[2-(4-trifluoromethylphenyl)ethyl]imidazole-4-carboxylate chemical structure, C14H13F3N2O2, CAS 175210-32-9
Methyl 2-[2-(4-trifluoromethylphenyl)ethyl]imidazole-4-carboxylate
CAS 175210-32-9C14H13F3N2O2
2-(2-Phenylethyl)-1H-imidazole-4-carboxylic acid chemical structure, C12H12N2O2, CAS 175210-33-0
2-(2-Phenylethyl)-1H-imidazole-4-carboxylic acid
CAS 175210-33-0C12H12N2O2
2-(1-Methyl-1H-imidazol-2-yl)-1-phenylethan-1-amine dihydrochloride chemical structure, C12H17Cl2N3, CAS 149928-41-6
2-(1-Methyl-1H-imidazol-2-yl)-1-phenylethan-1-amine dihydrochloride
CAS 149928-41-6C12H17Cl2N3
2-(1-Methyl-1H-imidazol-2-yl)-1-phenylethan-1-amine chemical structure, C12H15N3, CAS 149928-42-7
2-(1-Methyl-1H-imidazol-2-yl)-1-phenylethan-1-amine
CAS 149928-42-7C12H15N3
2-(1H-Imidazol-2-yl)-1-(3-methylphenyl)ethan-1-amine chemical structure, C12H15N3, CAS 1094644-91-3
2-(1H-Imidazol-2-yl)-1-(3-methylphenyl)ethan-1-amine
CAS 1094644-91-3C12H15N3
I+/--(3,5-Dichlorophenyl)-1H-imidazole-2-ethanamine chemical structure, C11H11Cl2N3, CAS 1152866-26-6
I+/--(3,5-Dichlorophenyl)-1H-imidazole-2-ethanamine
CAS 1152866-26-6C11H11Cl2N3
I+/--[3-(Trifluoromethyl)phenyl]-1H-imidazole-2-ethanamine chemical structure, C12H12F3N3, CAS 1094555-69-7
I+/--[3-(Trifluoromethyl)phenyl]-1H-imidazole-2-ethanamine
CAS 1094555-69-7C12H12F3N3
I+/--(2,3,4-Trimethoxyphenyl)-1H-imidazole-2-ethanamine chemical structure, C14H19N3O3, CAS 1156752-70-3
I+/--(2,3,4-Trimethoxyphenyl)-1H-imidazole-2-ethanamine
CAS 1156752-70-3C14H19N3O3
2-[2-(1-Methyl-1H-imidazol-2-yl)ethyl]-benzoic acid hydrochloride chemical structure, C13H15ClN2O2, CAS 1185294-32-9
2-[2-(1-Methyl-1H-imidazol-2-yl)ethyl]-benzoic acid hydrochloride
CAS 1185294-32-9C13H15ClN2O2
{4-[2-(1-Methyl-1H-imidazol-2-yl)ethyl]phenyl}-amine dihydrochloride chemical structure, C12H17Cl2N3, CAS 1185298-14-9
{4-[2-(1-Methyl-1H-imidazol-2-yl)ethyl]phenyl}-amine dihydrochloride
CAS 1185298-14-9C12H17Cl2N3
{2-[2-(1-Methyl-1H-imidazol-2-yl)ethyl]phenyl}-amine dihydrochloride chemical structure, C12H17Cl2N3, CAS 1185300-19-9
{2-[2-(1-Methyl-1H-imidazol-2-yl)ethyl]phenyl}-amine dihydrochloride
CAS 1185300-19-9C12H17Cl2N3
2-[1-(Difluoromethyl)-1H-imidazol-2-yl]-1-phenylethan-1-amine chemical structure, C12H13F2N3, CAS 1251922-76-5
2-[1-(Difluoromethyl)-1H-imidazol-2-yl]-1-phenylethan-1-amine
CAS 1251922-76-5C12H13F2N3
N-Ethyl-1-(1H-imidazol-2-yl)-2-phenylethanamine chemical structure, C13H17N3, CAS 886505-02-8
N-Ethyl-1-(1H-imidazol-2-yl)-2-phenylethanamine
CAS 886505-02-8C13H17N3
4-(Chloromethyl)-2-(2-phenylethyl)-1H-imidazole chemical structure, C12H13ClN2, CAS 52353-81-8
4-(Chloromethyl)-2-(2-phenylethyl)-1H-imidazole
CAS 52353-81-8C12H13ClN2