Murcko scaffold
N-Phenyloxolane-2-carboxamide scaffold
131 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 14
- Chemicals
- 131
- With full pages
- 50
Scaffold SMILES
O=C(Nc1ccccc1)C1CCCO1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 131 chemicals
Ethyl 4-(oxolane-2-carbonylamino)benzoate
CAS 545367-15-5C14H17NO4
Methyl 4-(oxolane-2-carbonylamino)benzoate
CAS 540788-68-9C13H15NO4
![4-Methyl-3-[(2S)-oxolane-2-amido]benzoic acid chemical structure, C13H15NO4, CAS 1913581-15-3](/s/GKSYTSXHEUFQLG-NSHDSACASA-N.svg)
4-Methyl-3-[(2S)-oxolane-2-amido]benzoic acid
CAS 1913581-15-3C13H15NO4
(2S)-N-(3-Chloro-2-methylphenyl)oxolane-2-carboxamide
CAS 2176362-38-0C12H14ClNO2
(2S)-N-(4-Carbamoylphenyl)oxolane-2-carboxamide
CAS 2188733-03-9C12H14N2O3
N-(2,4-Dichlorophenyl)oxolane-2-carboxamide
CAS 313385-82-9C11H11Cl2NO2
N-(Pentafluorophenyl)tetrahydrofuran-2-carboxamide
CAS 355811-65-3C11H8F5NO2
N-(5-Chloro-2-methoxyphenyl)oxolane-2-carboxamide
CAS 438614-06-3C12H14ClNO3
N-(4-Bromo-2-fluorophenyl)tetrahydrofuran-2-carboxamide
CAS 503563-95-9C11H11BrFNO2
N-(4-Fluoro-3-nitrophenyl)oxolane-2-carboxamide
CAS 544457-26-3C11H11FN2O4
N-(2-Chloro-4-nitrophenyl)oxolane-2-carboxamide
CAS 540532-58-9C11H11ClN2O4
N-(3-Chloro-4-fluorophenyl)tetrahydro-2-furancarboxamide
CAS 540528-50-5C11H11ClFNO2
![4-[[Oxo(2-oxolanyl)methyl]amino]benzoic acid butyl ester chemical structure, C16H21NO4, CAS 550315-07-6](/s/WEDABFJUBIFUAY-UHFFFAOYSA-N.svg)
4-[[Oxo(2-oxolanyl)methyl]amino]benzoic acid butyl ester
CAS 550315-07-6C16H21NO4
N-(2-Methyl-4-nitrophenyl)oxolane-2-carboxamide
CAS 546072-35-9C12H14N2O4
![Dimethyl 5-[(tetrahydro-2-furanylcarbonyl)amino]isophthalate chemical structure, C15H17NO6, CAS 445251-79-6](/s/PFCZCPVSHGSOQJ-UHFFFAOYSA-N.svg)
Dimethyl 5-[(tetrahydro-2-furanylcarbonyl)amino]isophthalate
CAS 445251-79-6C15H17NO6
Dimethyl 2-(oxolane-2-carbonylamino)benzene-1,4-dicarboxylate
CAS 354550-74-6C15H17NO6
N-(2-Methoxy-4-nitrophenyl)tetrahydrofuran-2-carboxamide
CAS 547707-22-2C12H14N2O5
N-(3-Chloro-4-methylphenyl)tetrahydro-2-furancarboxamide
CAS 560093-69-8C12H14ClNO2
N-(4-Sulfamoylphenyl)oxolane-2-carboxamide
CAS 543701-88-8C11H14N2O4S
N-(3-Methoxyphenyl)oxolane-2-carboxamide
CAS 540529-14-4C12H15NO3
N-(2,4-Dimethoxyphenyl)oxolane-2-carboxamide
CAS 544449-99-2C13H17NO4
![Methyl 2-[(tetrahydro-2-furanylcarbonyl)amino]benzoate chemical structure, C13H15NO4, CAS 495395-14-7](/s/RBBLRGUKNBEQKE-UHFFFAOYSA-N.svg)
Methyl 2-[(tetrahydro-2-furanylcarbonyl)amino]benzoate
CAS 495395-14-7C13H15NO4
N-(2-Ethyl-6-methylphenyl)tetrahydro-2-furancarboxamide
CAS 353770-33-9C14H19NO2
N-(4-Methyl-2-nitrophenyl)oxolane-2-carboxamide
CAS 438463-16-2C12H14N2O4
- N-(4-Iodophenyl)tetrahydrofuran-2-carboxamide438455-85-7C11H12INO2
- N-(3,5-Dichlorophenyl)tetrahydro-2-furancarboxamide540531-69-9C11H11Cl2NO2
- N-(5-Chloro-2,4-dimethoxyphenyl)oxolane-2-carboxamide503563-94-8C13H16ClNO4
- N-(4-Bromo-2-methylphenyl)oxolane-2-carboxamide503563-96-0C12H14BrNO2
- N-(3,5-Dichloro-4-hydroxyphenyl)oxolane-2-carboxamide500262-23-7C11H11Cl2NO3
- 5-[(Tetrahydro-furan-2-carbonyl)-amino]-isophthalic acid667409-87-2C13H13NO6
- 2-[(Tetrahydro-furan-2-carbonyl)-amino]-benzoic acid626218-00-6C12H13NO4
- 5-Hydroxy-2-(oxolane-2-carbonylamino)benzoic acid667409-89-4C12H13NO5
- 5-Bromo-2-[(tetrahydrofuran-2-ylcarbonyl)amino]benzoic acid667409-88-3C12H12BrNO4
- N-[4-(tert-Butylsulfamoyl)phenyl]oxolane-2-carboxamide600160-02-9C15H22N2O4S
- N-[5-(Diethylsulfamoyl)-2-methoxyphenyl]oxolane-2-carboxamide600159-93-1C16H24N2O5S
- N-Ethyl-N-phenyloxolane-2-carboxamide600159-57-7C13H17NO2
- N-(2-Methyl-3-nitrophenyl)tetrahydro-2-furancarboxamide600159-75-9C12H14N2O4
- Ethyl 3-(oxolane-2-carbonylamino)benzoate600159-76-0C14H17NO4
- Ethyl 2-[(tetrahydrofuran-2-ylcarbonyl)amino]benzoate438615-57-7C14H17NO4
- N-(4-Bromo-3-methylphenyl)tetrahydro-2-furancarboxamide600159-63-5C12H14BrNO2
- N-(2-Butan-2-ylphenyl)oxolane-2-carboxamide600159-92-0C15H21NO2
- N-(4-Fluoro-2-methylphenyl)tetrahydro-2-furancarboxamide774590-18-0C12H14FNO2
- N-(5-tert-Butyl-2-methoxyphenyl)oxolane-2-carboxamide774590-20-4C16H23NO3
- N-(3,4-Dimethoxyphenyl)oxolane-2-carboxamide774589-85-4C13H17NO4
- N-[4-(Trifluoromethyl)phenyl]oxolane-2-carboxamide774589-87-6C12H12F3NO2
- Methyl 4,5-dimethoxy-2-[(tetrahydro-2-furanylcarbonyl)amino]benzoate774589-88-7C15H19NO6
- 4-[(Tetrahydrofuran-2-ylcarbonyl)amino]benzoic acid706766-41-8C12H13NO4
- N-[4-(tert-Butylcarbamoyl)phenyl]oxolane-2-carboxamide832091-27-7C16H22N2O3
Related scaffolds
Same ring framework with different atoms or bond orders
O=C(Nc1ccccc1)c1ccco1208 chemicals
O=C(Nc1ccccc1)c1cccs1150 chemicals
O=C(Nc1nccs1)c1ccccc1121 chemicals![Scaffold O=C(N=c1[nH]ncs1)c1ccccc1](/scaffold/RWOUBULBQYRRNL-UHFFFAOYSA-N/structure.svg)
O=C(N=c1[nH]ncs1)c1ccccc187 chemicals
c1ccc(OCc2ccco2)cc175 chemicals
O=S(=O)(Nc1nccs1)c1ccccc161 chemicals![Scaffold c1ccc(CSc2ncn[nH]2)cc1](/scaffold/IQQYSQRJFHUASD-UHFFFAOYSA-N/structure.svg)
c1ccc(CSc2ncn[nH]2)cc160 chemicals![Scaffold O=C(Nc1ccccc1)c1cc[nH]n1](/scaffold/WMZYZYFPPQOFKY-UHFFFAOYSA-N/structure.svg)
O=C(Nc1ccccc1)c1cc[nH]n160 chemicals
O=C(Nc1cccs1)c1ccccc152 chemicals
O=C(Nc1ccccc1)c1ccoc148 chemicals
c1ccc(CSc2nncs2)cc144 chemicals
O=C(Nc1ccccc1)C1CCCC143 chemicals