Murcko scaffold
N-Phenylthiophene-2-carboxamide scaffold
643 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 14
- Chemicals
- 643
- With full pages
- 150
Scaffold SMILES
O=C(Nc1ccccc1)c1cccs1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 643 chemicals
Tibrofan
CAS 15686-72-3C11H6Br3NOS
Tienoxolol
CAS 90055-97-3C21H28N2O5S
N-(2-Acetylphenyl)thiophene-2-carboxamide
CAS 41242-35-7C13H11NO2S
N-(2-Methylsulfanylphenyl)thiophene-2-carboxamide
CAS 51942-34-8C12H11NOS2
N-(3-Bromophenyl)-5-nitrothiophene-2-carboxamide
CAS 308292-83-3C11H7BrN2O3S
N-(4-Fluorophenyl)-2-thiophenecarboxamide
CAS 136340-91-5C11H8FNOS
N-(3-Methylphenyl)-2-thiophenecarboxamide
CAS 39880-79-0C12H11NOS
N-(3-Chlorophenyl)thiophene-2-carboxamide
CAS 79822-82-5C11H8ClNOS
N-(4-Bromophenyl)thiophene-2-carboxamide
CAS 50428-20-1C11H8BrNOS
N-(2,5-Dimethoxyphenyl)-2-thiophenecarboxamide
CAS 314054-01-8C13H13NO3S
N-(3-Nitrophenyl)thiophene-2-carboxamide
CAS 39880-87-0C11H8N2O3S
N-(2-Fluorophenyl)thiophene-2-carboxamide
CAS 136340-93-7C11H8FNOS
Thiophene-2-carboxamide, N-ethyl-N-(3-methylphenyl)-
CAS 881589-61-3C14H15NOS
N-(2-Fluoro-5-nitrophenyl)-2-thiophenecarboxamide
CAS 316152-27-9C11H7FN2O3S
N-(2,6-Dimethylphenyl)thiophene-2-carboxamide
CAS 136341-01-0C13H13NOS
N-(3-Cyanophenyl)-2-thiophenecarboxamide
CAS 137272-72-1C12H8N2OS
N-(4-Acetylphenyl)thiophene-2-carboxamide
CAS 201351-83-9C13H11NO2S
N-(2-Isopropoxyphenyl)-2-thiophenecarboxamide
CAS 332026-30-9C14H15NO2S
N-(4-Iodophenyl)thiophene-2-carboxamide
CAS 136340-97-1C11H8INOS
![N-[4-(Acetylamino)phenyl]-2-thiophenecarboxamide chemical structure, C13H12N2O2S, CAS 316152-05-3](/s/LDFUCXYCKVBKKJ-UHFFFAOYSA-N.svg)
N-[4-(Acetylamino)phenyl]-2-thiophenecarboxamide
CAS 316152-05-3C13H12N2O2S
N-(4-Methoxyphenyl)-2-thiophenecarboxamide
CAS 64419-14-3C12H11NO2S
N-Mesityl-2-thiophenecarboxamide
CAS 70608-30-9C14H15NOS
N-(2-Cyanophenyl)thiophene-2-carboxamide
CAS 84197-49-9C12H8N2OS
![N-[4-(Cyanomethyl)phenyl]thiophene-2-carboxamide chemical structure, C13H10N2OS, CAS 332881-01-3](/s/REVMSZSIYLWEFH-UHFFFAOYSA-N.svg)
N-[4-(Cyanomethyl)phenyl]thiophene-2-carboxamide
CAS 332881-01-3C13H10N2OS
- N-[2-Chloro-5-(trifluoromethyl)phenyl]thiophene-2-carboxamide349097-43-4C12H7ClF3NOS
- 2-Thiophenecarboxamide, N-[2-(trifluoromethyl)phenyl]-137272-70-9C12H8F3NOS
- N-(4-Methoxy-2-nitrophenyl)thiophene-2-carboxamide312944-61-9C12H10N2O4S
- Methyl 4,5-dimethoxy-2-(thiophene-2-carbonylamino)benzoate385392-34-7C15H15NO5S
- N-(4-Chlorophenyl)-3-ethoxy-2-thiophenecarboxamide677277-40-6C13H12ClNO2S
- 5-Bromo-N-phenylthiophene-2-carboxamide66259-11-8C11H8BrNOS
- 2-(Thiophene-2-amido)benzoic acid33405-06-0C12H9NO3S
- Ethyl 3-[(2-thienylcarbonyl)amino]benzoate300827-76-3C14H13NO3S
- N-(4-Amino-2-chlorophenyl)thiophene-2-carboxamide305357-99-7C11H9ClN2OS
- N-(2-Chlorophenyl)thiophene-2-carboxamide136340-94-8C11H8ClNOS
- N-(5-Amino-2-chlorophenyl)thiophene-2-carboxamide625078-84-4C11H9ClN2OS
- N-(4-Ethylphenyl)thiophene-2-carboxamide136340-88-0C13H13NOS
- 1 suppliersN-[3-(Trifluoromethyl)phenyl]thiophene-2-carboxamide15950-39-7C12H8F3NOS
- N-(3,5-Dichlorophenyl)thiophene-2-carboxamide316152-22-4C11H7Cl2NOS
- N-(3,4-Dimethylphenyl)thiophene-2-carboxamide316152-12-2C13H13NOS
- N-(5-Chloro-2-methoxyphenyl)thiophene-2-carboxamide313981-46-3C12H10ClNO2S
- N-(2-Ethoxyphenyl)thiophene-2-carboxamide5347-76-2C13H13NO2S
- Dimethyl 2-(thiophene-2-carbonylamino)benzene-1,4-dicarboxylate330466-64-3C15H13NO5S
- N-(3-Acetamidophenyl)thiophene-2-carboxamide326901-72-8C13H12N2O2S
- N-[4-(Acetylsulfamoyl)phenyl]thiophene-2-carboxamide310418-34-9C13H12N2O4S2
- N-(3,4-Dimethoxyphenyl)thiophene-2-carboxamide330646-61-2C13H13NO3S
- Ethyl 2-amino-5-[(2,4-dimethylphenyl)carbamoyl]-4-methylthiophene-3-carboxylate329082-05-5C17H20N2O3S
- N-(3-Acetylphenyl)thiophene-2-carboxamide201354-21-4C13H11NO2S
- N-(3-Chloro-2-methylphenyl)thiophene-2-carboxamide330459-24-0C12H10ClNOS
Related scaffolds
Same ring framework with different atoms or bond orders
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O=C(Nc1nccs1)c1ccccc1121 chemicals![Scaffold O=C(N=c1[nH]ncs1)c1ccccc1](/scaffold/RWOUBULBQYRRNL-UHFFFAOYSA-N/structure.svg)
O=C(N=c1[nH]ncs1)c1ccccc187 chemicals
c1ccc(OCc2ccco2)cc175 chemicals
O=S(=O)(Nc1nccs1)c1ccccc161 chemicals![Scaffold c1ccc(CSc2ncn[nH]2)cc1](/scaffold/IQQYSQRJFHUASD-UHFFFAOYSA-N/structure.svg)
c1ccc(CSc2ncn[nH]2)cc160 chemicals![Scaffold O=C(Nc1ccccc1)c1cc[nH]n1](/scaffold/WMZYZYFPPQOFKY-UHFFFAOYSA-N/structure.svg)
O=C(Nc1ccccc1)c1cc[nH]n160 chemicals
O=C(Nc1cccs1)c1ccccc152 chemicals
O=C(Nc1ccccc1)C1CCCO150 chemicals
O=C(Nc1ccccc1)c1ccoc148 chemicals
c1ccc(CSc2nncs2)cc144 chemicals
O=C(Nc1ccccc1)C1CCCC143 chemicals