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Murcko scaffold

Ring system with 4 rings and 28 atoms

8 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
28
Chemicals
8
With full pages
4
Scaffold SMILES

O=C1Nc2ccccc2C1=Cc1cc(C(=O)NCCCN2CCOCC2)c[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1Nc2ccccc2C1=Cc1cc(C(=O)NCCCN2CCOCC2)c[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

Su-14813 chemical structure, C23H27FN4O4, CAS 452105-23-6
Su-14813
CAS 452105-23-6C23H27FN4O4
5-[((3Z)-5-Fluoro-2-oxo-1,2-dihydroindol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxylic acid [2-hydroxy-3-(morpholin-4-yl)propyl]amide chemical structure, C23H27FN4O4, CAS 627908-92-3
5-[((3Z)-5-Fluoro-2-oxo-1,2-dihydroindol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxylic acid [2-hydroxy-3-(morpholin-4-yl)propyl]amide
CAS 627908-92-3C23H27FN4O4
SU14813 maleate chemical structure, C27H31FN4O8, CAS 849643-15-8
SU14813 maleate
CAS 849643-15-8C27H31FN4O8
5-[(5-Fluoro-2-oxo-1H-indol-3-ylidene)methyl]-N-[(2S)-2-hydroxy-3-morpholin-4-ylpropyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide chemical structure, C23H27FN4O4
5-[(5-Fluoro-2-oxo-1H-indol-3-ylidene)methyl]-N-[(2S)-2-hydroxy-3-morpholin-4-ylpropyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide
C23H27FN4O4
(Z)-5-((5-Fluoro-2-oxoindolin-3-ylidene)methyl)-N-(2-hydroxy-3-morpholinopropyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide chemical structure, C23H27FN4O4
(Z)-5-((5-Fluoro-2-oxoindolin-3-ylidene)methyl)-N-(2-hydroxy-3-morpholinopropyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide
C23H27FN4O4
1H-Pyrrole-3-carboxamide,5-[(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-N-[(2S)-2-hydroxy-3-(4-morpholinyl)propyl]-2,4-dimethyl- chemical structure, C23H27FN4O4
1H-Pyrrole-3-carboxamide,5-[(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-N-[(2S)-2-hydroxy-3-(4-morpholinyl)propyl]-2,4-dimethyl-
C23H27FN4O4
SU14813 maleate chemical structure, C27H31FN4O8
SU14813 maleate
C27H31FN4O8
But-2-enedioic acid, 5-[(Z)-(5-fluoro-2-oxo-1H-indol-3-ylidene)methyl]-N-[(2S)-2-hydroxy-3-morpholin-4-ylpropyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide chemical structure, C27H31FN4O8
But-2-enedioic acid, 5-[(Z)-(5-fluoro-2-oxo-1H-indol-3-ylidene)methyl]-N-[(2S)-2-hydroxy-3-morpholin-4-ylpropyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide
C27H31FN4O8