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Murcko scaffold

Ring system with 2 rings and 15 atoms

7 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
15
Chemicals
7
With full pages
3
Scaffold SMILES

O=S1(=O)CCC(N=Cc2ccccc2)C1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=S1(=O)CCC(N=Cc2ccccc2)C1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 7 of 7 chemicals

4-Bromo-2-{(E)-[(1,1-dioxidotetrahydrothiophen-3-yl)imino]methyl}phenol chemical structure, C11H12BrNO3S, CAS 331658-30-1
4-Bromo-2-{(E)-[(1,1-dioxidotetrahydrothiophen-3-yl)imino]methyl}phenol
CAS 331658-30-1C11H12BrNO3S
N-[(E)-(2-Chlorophenyl)methylidene]tetrahydrothiophen-3-amine 1,1-dioxide chemical structure, C11H12ClNO2S, CAS 306279-20-9
N-[(E)-(2-Chlorophenyl)methylidene]tetrahydrothiophen-3-amine 1,1-dioxide
CAS 306279-20-9C11H12ClNO2S
(1,1-Dioxo-tetrahydro-thiophen-3-yl)-(4-methoxy-benzylidene)-amine chemical structure, C12H15NO3S, CAS 324069-50-3
(1,1-Dioxo-tetrahydro-thiophen-3-yl)-(4-methoxy-benzylidene)-amine
CAS 324069-50-3C12H15NO3S
2-{(E)-[(3-Methyl-1,1-dioxidotetrahydrothiophen-3-yl)imino]methyl}phenol chemical structure, C12H15NO3S, CAS 507459-12-3
2-{(E)-[(3-Methyl-1,1-dioxidotetrahydrothiophen-3-yl)imino]methyl}phenol
CAS 507459-12-3C12H15NO3S
2-{(E)-[(1,1-Dioxidotetrahydrothiophen-3-yl)imino]methyl}phenol chemical structure, C11H13NO3S, CAS 443781-85-9
2-{(E)-[(1,1-Dioxidotetrahydrothiophen-3-yl)imino]methyl}phenol
CAS 443781-85-9C11H13NO3S
N-(3-Methyl-1,1-dioxothiolan-3-yl)-1-phenylmethanimine chemical structure, C12H15NO2S, CAS 5416-91-1
N-(3-Methyl-1,1-dioxothiolan-3-yl)-1-phenylmethanimine
CAS 5416-91-1C12H15NO2S
3-{[(2-Chloro-6-fluorophenyl)methylidene]amino}-1lambda6-thiolane-1,1-dione chemical structure, C11H11ClFNO2S, CAS 872455-55-5
3-{[(2-Chloro-6-fluorophenyl)methylidene]amino}-1lambda6-thiolane-1,1-dione
CAS 872455-55-5C11H11ClFNO2S