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Murcko scaffold

Ring system with 4 rings and 20 atoms

6 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
20
Chemicals
6
With full pages
3
Scaffold SMILES

c1ccc(Cn2c3ccccc3c3nncnc32)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(Cn2c3ccccc3c3nncnc32)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

2-((5-Benzyl-5H-[1,2,4]triazino[5,6-b]indol-3-yl)thio)acetic acid chemical structure, C18H14N4O2S, CAS 443121-77-5
2-((5-Benzyl-5H-[1,2,4]triazino[5,6-b]indol-3-yl)thio)acetic acid
CAS 443121-77-5C18H14N4O2S
Methyl 2-[(5-benzyl-5H-[1,2,4]triazino[5,6-b]indol-3-yl)sulfanyl]propanoate chemical structure, C20H18N4O2S, CAS 710983-29-2
Methyl 2-[(5-benzyl-5H-[1,2,4]triazino[5,6-b]indol-3-yl)sulfanyl]propanoate
CAS 710983-29-2C20H18N4O2S
5-Benzyl-3-methylsulfanyl-[1,2,4]triazino[5,6-b]indole chemical structure, C17H14N4S, CAS 827011-68-7
5-Benzyl-3-methylsulfanyl-[1,2,4]triazino[5,6-b]indole
CAS 827011-68-7C17H14N4S
2-[(5-Benzyl-[1,2,4]triazino[5,6-b]indol-3-yl)sulfanyl]-N,N-diethylethanamine chemical structure, C22H25N5S, CAS 830338-52-8
2-[(5-Benzyl-[1,2,4]triazino[5,6-b]indol-3-yl)sulfanyl]-N,N-diethylethanamine
CAS 830338-52-8C22H25N5S
5-Benzyl-8-fluoro-3-methylsulfanyl-[1,2,4]triazino[5,6-b]indole chemical structure, C17H13FN4S, CAS 838897-72-6
5-Benzyl-8-fluoro-3-methylsulfanyl-[1,2,4]triazino[5,6-b]indole
CAS 838897-72-6C17H13FN4S
5-Benzyl-8-fluoro-3-hydrazinyl-5H-[1,2,4]triazino[5,6-b]indole chemical structure, C16H13FN6, CAS 846587-03-9
5-Benzyl-8-fluoro-3-hydrazinyl-5H-[1,2,4]triazino[5,6-b]indole
CAS 846587-03-9C16H13FN6