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Murcko scaffold

3-Phenyl-1-thioxo[1,3]thiazolo[3,4-a]quinazolin-5(4H)-one scaffold

11 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
21
Chemicals
11
With full pages
1
Scaffold SMILES

O=c1[nH]c2c(-c3ccccc3)sc(=S)n2c2ccccc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 3-Phenyl-1-thioxo[1,3]thiazolo[3,4-a]quinazolin-5(4H)-one page
Murcko scaffold O=c1[nH]c2c(-c3ccccc3)sc(=S)n2c2ccccc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 11 of 11 chemicals

2-[3-(3-Methylphenyl)-5-oxo-1-sulfanylidene-[1,3]thiazolo[3,4-a]quinazolin-4-yl]-N,N-dipropylacetamide chemical structure, C25H27N3O2S2, CAS 872197-57-4
2-[3-(3-Methylphenyl)-5-oxo-1-sulfanylidene-[1,3]thiazolo[3,4-a]quinazolin-4-yl]-N,N-dipropylacetamide
CAS 872197-57-4C25H27N3O2S2
4-Isopropyl-1-thioxo-3-(o-tolyl)-1H-thiazolo[3,4-a]quinazolin-5(4H)-one chemical structure, C20H18N2OS2, CAS 872197-61-0
4-Isopropyl-1-thioxo-3-(o-tolyl)-1H-thiazolo[3,4-a]quinazolin-5(4H)-one
CAS 872197-61-0C20H18N2OS2
2-[3-(2-Methylphenyl)-5-oxo-1-sulfanylidene-[1,3]thiazolo[3,4-a]quinazolin-4-yl]-N,N-dipropylacetamide chemical structure, C25H27N3O2S2, CAS 872197-64-3
2-[3-(2-Methylphenyl)-5-oxo-1-sulfanylidene-[1,3]thiazolo[3,4-a]quinazolin-4-yl]-N,N-dipropylacetamide
CAS 872197-64-3C25H27N3O2S2
N,N-Diethyl-2-(5-oxo-1-thioxo-3-(o-tolyl)-1H-thiazolo[3,4-a]quinazolin-4(5H)-yl)acetamide chemical structure, C23H23N3O2S2, CAS 872197-62-1
N,N-Diethyl-2-(5-oxo-1-thioxo-3-(o-tolyl)-1H-thiazolo[3,4-a]quinazolin-4(5H)-yl)acetamide
CAS 872197-62-1C23H23N3O2S2
2-{5-Oxo-3-phenyl-1-sulfanylidene-1H,4H,5H-[1,3]thiazolo[3,4-a]quinazolin-4-yl}-N,N-dipropylacetamide chemical structure, C24H25N3O2S2, CAS 902899-50-7
2-{5-Oxo-3-phenyl-1-sulfanylidene-1H,4H,5H-[1,3]thiazolo[3,4-a]quinazolin-4-yl}-N,N-dipropylacetamide
CAS 902899-50-7C24H25N3O2S2
3-(3-Chlorophenyl)-1-thioxo[1,3]thiazolo[3,4-a]quinazolin-5(4H)-one chemical structure, C16H9ClN2OS2, CAS 950270-46-9
3-(3-Chlorophenyl)-1-thioxo[1,3]thiazolo[3,4-a]quinazolin-5(4H)-one
CAS 950270-46-9C16H9ClN2OS2
3-(2-Chlorophenyl)-1-thioxo[1,3]thiazolo[3,4-a]quinazolin-5(4H)-one chemical structure, C16H9ClN2OS2, CAS 950258-80-7
3-(2-Chlorophenyl)-1-thioxo[1,3]thiazolo[3,4-a]quinazolin-5(4H)-one
CAS 950258-80-7C16H9ClN2OS2
3-(3-Methylphenyl)-1-sulfanylidene-1H,4H,5H-[1,3]thiazolo[3,4-a]quinazolin-5-one chemical structure, C17H12N2OS2, CAS 950270-50-5
3-(3-Methylphenyl)-1-sulfanylidene-1H,4H,5H-[1,3]thiazolo[3,4-a]quinazolin-5-one
CAS 950270-50-5C17H12N2OS2
3-Phenyl-1-thioxo[1,3]thiazolo[3,4-a]quinazolin-5(4H)-one chemical structure, C16H10N2OS2, CAS 950258-82-9
3-Phenyl-1-thioxo[1,3]thiazolo[3,4-a]quinazolin-5(4H)-one
CAS 950258-82-9C16H10N2OS2
3-(4-Chlorophenyl)-1-thioxo-1H-thiazolo[3,4-a]quinazolin-5(4H)-one chemical structure, C16H9ClN2OS2, CAS 950270-52-7
3-(4-Chlorophenyl)-1-thioxo-1H-thiazolo[3,4-a]quinazolin-5(4H)-one
CAS 950270-52-7C16H9ClN2OS2
3-(2,4-Dichlorophenyl)-1-thioxo[1,3]thiazolo[3,4-a]quinazolin-5(4H)-one chemical structure, C16H8Cl2N2OS2, CAS 950258-86-3
3-(2,4-Dichlorophenyl)-1-thioxo[1,3]thiazolo[3,4-a]quinazolin-5(4H)-one
CAS 950258-86-3C16H8Cl2N2OS2