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Murcko scaffold

2,3-Dihydroindolizin-5(1H)-one scaffold

59 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
59
With full pages
5
Scaffold SMILES

O=c1cccc2n1CCC2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2,3-Dihydroindolizin-5(1H)-one page
Murcko scaffold O=c1cccc2n1CCC2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 59 chemicals

6-Indolizinepropanoic acid, 3-carboxy-1,2,3,5-tetrahydro-8-hydroxy-5-oxo-, (-)- chemical structure, C12H13NO6, CAS 87896-52-4
6-Indolizinepropanoic acid, 3-carboxy-1,2,3,5-tetrahydro-8-hydroxy-5-oxo-, (-)-
CAS 87896-52-4C12H13NO6
Methyl 7-(2-methoxy-2-oxoethyl)-5-oxo-1,2,3,5-tetrahydro-8-indolizinecarboxylate chemical structure, C13H15NO5, CAS 145474-06-2
Methyl 7-(2-methoxy-2-oxoethyl)-5-oxo-1,2,3,5-tetrahydro-8-indolizinecarboxylate
CAS 145474-06-2C13H15NO5
Methyl 5-oxo-1,2,3,5-tetrahydroindolizine-8-carboxylate chemical structure, C10H11NO3, CAS 87286-02-0
Methyl 5-oxo-1,2,3,5-tetrahydroindolizine-8-carboxylate
CAS 87286-02-0C10H11NO3
Methyl 5-oxo-6-[(trifluoromethanesulfonyl)oxy]-1,2,3,5-tetrahydroindolizine-8-carboxylate chemical structure, C11H10F3NO6S, CAS 253195-64-1
Methyl 5-oxo-6-[(trifluoromethanesulfonyl)oxy]-1,2,3,5-tetrahydroindolizine-8-carboxylate
CAS 253195-64-1C11H10F3NO6S
Methyl 6-hydroxy-5-oxo-1,2,3,5-tetrahydroindolizine-8-carboxylate chemical structure, C10H11NO4, CAS 185198-42-9
Methyl 6-hydroxy-5-oxo-1,2,3,5-tetrahydroindolizine-8-carboxylate
CAS 185198-42-9C10H11NO4
8-Bromo-2,3-dihydro-1H-indolizin-5-one chemical structure, C8H8BrNO, CAS 253195-80-1
8-Bromo-2,3-dihydro-1H-indolizin-5-one
CAS 253195-80-1C8H8BrNO
6-Hydroxy-2,3-dihydroindolizin-5(1H)-one chemical structure, C8H9NO2, CAS 253195-68-5
6-Hydroxy-2,3-dihydroindolizin-5(1H)-one
CAS 253195-68-5C8H9NO2
6-Amino-5-oxo-1,2,3,5-tetrahydroindolizine-8-carboxylic acid chemical structure, C9H10N2O3, CAS 185856-19-3
6-Amino-5-oxo-1,2,3,5-tetrahydroindolizine-8-carboxylic acid
CAS 185856-19-3C9H10N2O3
6-Hydroxy-7-pent-1-en-3-yl-2,3-dihydro-1H-indolizin-5-one chemical structure, C13H17NO2, CAS 642069-71-4
6-Hydroxy-7-pent-1-en-3-yl-2,3-dihydro-1H-indolizin-5-one
CAS 642069-71-4C13H17NO2
5-Oxo-6-trifluoromethanesulfonyloxy-1,2,3,5-tetrahydroindolizine chemical structure, C9H8F3NO4S, CAS 612065-04-0
5-Oxo-6-trifluoromethanesulfonyloxy-1,2,3,5-tetrahydroindolizine
CAS 612065-04-0C9H8F3NO4S
Methyl 6-hydroxy-7-(2-methylallyl)-5-oxo-1,2,3,5-tetrahydroindolizine-8-carboxylate chemical structure, C14H17NO4, CAS 866393-53-5
Methyl 6-hydroxy-7-(2-methylallyl)-5-oxo-1,2,3,5-tetrahydroindolizine-8-carboxylate
CAS 866393-53-5C14H17NO4
Methyl 6-hydroxy-7-(1-methylallyl)-5-oxo-1,2,3,5-tetrahydroindolizine-8-carboxylate chemical structure, C14H17NO4, CAS 866393-52-4
Methyl 6-hydroxy-7-(1-methylallyl)-5-oxo-1,2,3,5-tetrahydroindolizine-8-carboxylate
CAS 866393-52-4C14H17NO4
Methyl 7-allyl-6-hydroxy-5-oxo-1,2,3,5-tetrahydroindolizine-8-carboxylate chemical structure, C13H15NO4, CAS 866393-51-3
Methyl 7-allyl-6-hydroxy-5-oxo-1,2,3,5-tetrahydroindolizine-8-carboxylate
CAS 866393-51-3C13H15NO4
Ethyl 5-oxo-1,2,3,5-tetrahydroindolizine-8-carboxylate chemical structure, C11H13NO3, CAS 87273-80-1
Ethyl 5-oxo-1,2,3,5-tetrahydroindolizine-8-carboxylate
CAS 87273-80-1C11H13NO3
2,3-Dihydroindolizin-5(1H)-one chemical structure, C8H9NO, CAS 101773-62-0
2,3-Dihydroindolizin-5(1H)-one
CAS 101773-62-0C8H9NO
6,7-Bis(trimethylsilyl)-2,3-dihydroindolizin-5(1H)-one chemical structure, C14H25NOSi2, CAS 88761-32-4
6,7-Bis(trimethylsilyl)-2,3-dihydroindolizin-5(1H)-one
CAS 88761-32-4C14H25NOSi2
7-Ethoxy-5-oxo-1,2,3,5-tetrahydroindolizine-8-carboxylic acid chemical structure, C11H13NO4, CAS 1291846-05-3
7-Ethoxy-5-oxo-1,2,3,5-tetrahydroindolizine-8-carboxylic acid
CAS 1291846-05-3C11H13NO4
7-Chloro-5-oxo-1,2,3,5-tetrahydroindolizine-8-carboxylic acid chemical structure, C9H8ClNO3, CAS 1150098-39-7
7-Chloro-5-oxo-1,2,3,5-tetrahydroindolizine-8-carboxylic acid
CAS 1150098-39-7C9H8ClNO3
Ethyl 7-hydroxy-5-oxo-1,2,3,5-tetrahydroindolizine-8-carboxylate chemical structure, C11H13NO4, CAS 72130-68-8
Ethyl 7-hydroxy-5-oxo-1,2,3,5-tetrahydroindolizine-8-carboxylate
CAS 72130-68-8C11H13NO4
7-Hydroxy-2,3-dihydro-1H-indolizin-5-one chemical structure, C8H9NO2, CAS 58156-35-7
7-Hydroxy-2,3-dihydro-1H-indolizin-5-one
CAS 58156-35-7C8H9NO2
Ethyl 7-hydroxy-6-methyl-5-oxo-1,2,3,5-tetrahydroindolizine-8-carboxylate chemical structure, C12H15NO4, CAS 116993-42-1
Ethyl 7-hydroxy-6-methyl-5-oxo-1,2,3,5-tetrahydroindolizine-8-carboxylate
CAS 116993-42-1C12H15NO4
7-Hydroxy-5-oxo-1,2,3,5-tetrahydroindolizine-8-carboxylic acid chemical structure, C9H9NO4, CAS 116993-46-5
7-Hydroxy-5-oxo-1,2,3,5-tetrahydroindolizine-8-carboxylic acid
CAS 116993-46-5C9H9NO4
Methyl 7-hydroxy-5-oxo-1,2,3,5-tetrahydroindolizine-8-carboxylate chemical structure, C10H11NO4, CAS 37704-45-3
Methyl 7-hydroxy-5-oxo-1,2,3,5-tetrahydroindolizine-8-carboxylate
CAS 37704-45-3C10H11NO4
7-(Hydroxymethyl)-2,3-dihydro-5(1H)-indolizinone chemical structure, C9H11NO2, CAS 944407-77-6
7-(Hydroxymethyl)-2,3-dihydro-5(1H)-indolizinone
CAS 944407-77-6C9H11NO2