CompoundList
Sign in
Murcko scaffold

Ring system with 2 rings and 14 atoms

26 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
14
Chemicals
26
With full pages
3
Scaffold SMILES

O=C1CC(Nc2ccccc2)C(=O)N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1CC(Nc2ccccc2)C(=O)N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 26 of 26 chemicals

1-(Dimethylamino)-3-(4-toluidino)pyrrolidine-2,5-dione chemical structure, C13H17N3O2, CAS 464920-33-0
1-(Dimethylamino)-3-(4-toluidino)pyrrolidine-2,5-dione
CAS 464920-33-0C13H17N3O2
1-(Dimethylamino)-3-(3-methylanilino)pyrrolidine-2,5-dione chemical structure, C13H17N3O2, CAS 464920-37-4
1-(Dimethylamino)-3-(3-methylanilino)pyrrolidine-2,5-dione
CAS 464920-37-4C13H17N3O2
3-(4-Ethylanilino)pyrrolidine-2,5-dione chemical structure, C12H14N2O2, CAS 1008462-77-8
3-(4-Ethylanilino)pyrrolidine-2,5-dione
CAS 1008462-77-8C12H14N2O2
1-Butyl-3-((4-ethylphenyl)amino)pyrrolidine-2,5-dione chemical structure, C16H22N2O2, CAS 1008036-41-6
1-Butyl-3-((4-ethylphenyl)amino)pyrrolidine-2,5-dione
CAS 1008036-41-6C16H22N2O2
1-Isopropyl-3-((4-methoxyphenyl)amino)pyrrolidine-2,5-dione chemical structure, C14H18N2O3, CAS 1008463-68-0
1-Isopropyl-3-((4-methoxyphenyl)amino)pyrrolidine-2,5-dione
CAS 1008463-68-0C14H18N2O3
3-[4-(Dimethylamino)anilino]pyrrolidine-2,5-dione chemical structure, C12H15N3O2, CAS 1008189-04-5
3-[4-(Dimethylamino)anilino]pyrrolidine-2,5-dione
CAS 1008189-04-5C12H15N3O2
3-{[4-(Dimethylamino)phenyl]amino}-1-propylazolidine-2,5-dione chemical structure, C15H21N3O2, CAS 1009289-69-3
3-{[4-(Dimethylamino)phenyl]amino}-1-propylazolidine-2,5-dione
CAS 1009289-69-3C15H21N3O2
3-((4-(Dimethylamino)phenyl)amino)-1-(2-methoxyethyl)pyrrolidine-2,5-dione chemical structure, C15H21N3O3, CAS 1009289-71-7
3-((4-(Dimethylamino)phenyl)amino)-1-(2-methoxyethyl)pyrrolidine-2,5-dione
CAS 1009289-71-7C15H21N3O3
3-((4-Ethoxyphenyl)amino)-1-(2-methoxyethyl)pyrrolidine-2,5-dione chemical structure, C15H20N2O4, CAS 1009482-74-9
3-((4-Ethoxyphenyl)amino)-1-(2-methoxyethyl)pyrrolidine-2,5-dione
CAS 1009482-74-9C15H20N2O4
3-((4-(Dimethylamino)phenyl)amino)-1-ethylpyrrolidine-2,5-dione chemical structure, C14H19N3O2, CAS 1008960-27-7
3-((4-(Dimethylamino)phenyl)amino)-1-ethylpyrrolidine-2,5-dione
CAS 1008960-27-7C14H19N3O2
3-((4-Ethoxyphenyl)amino)-1-isopropylpyrrolidine-2,5-dione chemical structure, C15H20N2O3, CAS 1009672-70-1
3-((4-Ethoxyphenyl)amino)-1-isopropylpyrrolidine-2,5-dione
CAS 1009672-70-1C15H20N2O3
3-((4-Ethoxyphenyl)amino)-1-methylpyrrolidine-2,5-dione chemical structure, C13H16N2O3, CAS 1008579-67-6
3-((4-Ethoxyphenyl)amino)-1-methylpyrrolidine-2,5-dione
CAS 1008579-67-6C13H16N2O3
3-((4-(Dimethylamino)phenyl)amino)-1-methylpyrrolidine-2,5-dione chemical structure, C13H17N3O2, CAS 1009234-80-3
3-((4-(Dimethylamino)phenyl)amino)-1-methylpyrrolidine-2,5-dione
CAS 1009234-80-3C13H17N3O2
3-(4-Fluoroanilino)-1-(3-methoxypropyl)pyrrolidine-2,5-dione chemical structure, C14H17FN2O3, CAS 1009261-02-2
3-(4-Fluoroanilino)-1-(3-methoxypropyl)pyrrolidine-2,5-dione
CAS 1009261-02-2C14H17FN2O3
3-(4-Methoxyanilino)-1-prop-2-enylpyrrolidine-2,5-dione chemical structure, C14H16N2O3, CAS 1008080-68-9
3-(4-Methoxyanilino)-1-prop-2-enylpyrrolidine-2,5-dione
CAS 1008080-68-9C14H16N2O3
3-((4-Methoxyphenyl)amino)-1-(3-methoxypropyl)pyrrolidine-2,5-dione chemical structure, C15H20N2O4, CAS 1009339-08-5
3-((4-Methoxyphenyl)amino)-1-(3-methoxypropyl)pyrrolidine-2,5-dione
CAS 1009339-08-5C15H20N2O4
1-Allyl-3-((4-ethylphenyl)amino)pyrrolidine-2,5-dione chemical structure, C15H18N2O2, CAS 1008668-03-8
1-Allyl-3-((4-ethylphenyl)amino)pyrrolidine-2,5-dione
CAS 1008668-03-8C15H18N2O2
3-Anilino-1-(triethylstannyl)pyrrolidine-2,5-dione chemical structure, C16H24N2O2Sn, CAS 74595-33-8
3-Anilino-1-(triethylstannyl)pyrrolidine-2,5-dione
CAS 74595-33-8C16H24N2O2Sn
3-((4-(Dimethylamino)phenyl)amino)-1-(3-methoxypropyl)pyrrolidine-2,5-dione chemical structure, C16H23N3O3, CAS 1009697-83-9
3-((4-(Dimethylamino)phenyl)amino)-1-(3-methoxypropyl)pyrrolidine-2,5-dione
CAS 1009697-83-9C16H23N3O3
1-Butyl-3-((4-(dimethylamino)phenyl)amino)pyrrolidine-2,5-dione chemical structure, C16H23N3O2, CAS 1025395-87-2
1-Butyl-3-((4-(dimethylamino)phenyl)amino)pyrrolidine-2,5-dione
CAS 1025395-87-2C16H23N3O2
1-Allyl-3-((4-(dimethylamino)phenyl)amino)pyrrolidine-2,5-dione chemical structure, C15H19N3O2, CAS 1025396-01-3
1-Allyl-3-((4-(dimethylamino)phenyl)amino)pyrrolidine-2,5-dione
CAS 1025396-01-3C15H19N3O2
3-((4-(Dimethylamino)phenyl)amino)-1-isobutylpyrrolidine-2,5-dione chemical structure, C16H23N3O2, CAS 1032268-11-3
3-((4-(Dimethylamino)phenyl)amino)-1-isobutylpyrrolidine-2,5-dione
CAS 1032268-11-3C16H23N3O2
1-Methyl-3-[(4-methylphenyl)amino]pyrrolidine-2,5-dione chemical structure, C12H14N2O2, CAS 41260-54-2
1-Methyl-3-[(4-methylphenyl)amino]pyrrolidine-2,5-dione
CAS 41260-54-2C12H14N2O2
3-((3-Chloro-4-methoxyphenyl)amino)-1-methylpyrrolidine-2,5-dione chemical structure, C12H13ClN2O3, CAS 1105044-28-7
3-((3-Chloro-4-methoxyphenyl)amino)-1-methylpyrrolidine-2,5-dione
CAS 1105044-28-7C12H13ClN2O3