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Murcko scaffold

Ring system with 4 rings and 24 atoms

15 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
24
Chemicals
15
With full pages
5
Scaffold SMILES

O=C(c1cc2ccccc2oc1=O)N1CCSC1c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(c1cc2ccccc2oc1=O)N1CCSC1c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 15 of 15 chemicals

3-{[2-(4-Bromophenyl)-1,3-thiazolidin-3-yl]carbonyl}-2H-chromen-2-one chemical structure, C19H14BrNO3S, CAS 313266-89-6
3-{[2-(4-Bromophenyl)-1,3-thiazolidin-3-yl]carbonyl}-2H-chromen-2-one
CAS 313266-89-6C19H14BrNO3S
3-{[2-(4-Methoxyphenyl)-1,3-thiazolidin-3-yl]carbonyl}-2H-chromen-2-one chemical structure, C20H17NO4S, CAS 313266-88-5
3-{[2-(4-Methoxyphenyl)-1,3-thiazolidin-3-yl]carbonyl}-2H-chromen-2-one
CAS 313266-88-5C20H17NO4S
6-Bromo-3-(2-(4-nitrophenyl)thiazolidine-3-carbonyl)-2H-chromen-2-one chemical structure, C19H13BrN2O5S, CAS 361995-28-0
6-Bromo-3-(2-(4-nitrophenyl)thiazolidine-3-carbonyl)-2H-chromen-2-one
CAS 361995-28-0C19H13BrN2O5S
6-Bromo-3-{2-[4-(dimethylamino)phenyl]-1,3-thiazolidine-3-carbonyl}-2H-chromen-2-one chemical structure, C21H19BrN2O3S, CAS 361995-62-2
6-Bromo-3-{2-[4-(dimethylamino)phenyl]-1,3-thiazolidine-3-carbonyl}-2H-chromen-2-one
CAS 361995-62-2C21H19BrN2O3S
6-Bromo-3-[2-(4-methoxy-phenyl)-thiazolidine-3-carbonyl]-chromen-2-one chemical structure, C20H16BrNO4S, CAS 294874-58-1
6-Bromo-3-[2-(4-methoxy-phenyl)-thiazolidine-3-carbonyl]-chromen-2-one
CAS 294874-58-1C20H16BrNO4S
3-(2-(4-Nitrophenyl)thiazolidine-3-carbonyl)-2H-chromen-2-one chemical structure, C19H14N2O5S, CAS 337353-37-4
3-(2-(4-Nitrophenyl)thiazolidine-3-carbonyl)-2H-chromen-2-one
CAS 337353-37-4C19H14N2O5S
3-[2-(2,4,5-Trimethoxy-phenyl)-thiazolidine-3-carbonyl]-chromen-2-one chemical structure, C22H21NO6S, CAS 337353-49-8
3-[2-(2,4,5-Trimethoxy-phenyl)-thiazolidine-3-carbonyl]-chromen-2-one
CAS 337353-49-8C22H21NO6S
3-(2-(4-(Dimethylamino)phenyl)thiazolidine-3-carbonyl)-2H-chromen-2-one chemical structure, C21H20N2O3S, CAS 372506-82-6
3-(2-(4-(Dimethylamino)phenyl)thiazolidine-3-carbonyl)-2H-chromen-2-one
CAS 372506-82-6C21H20N2O3S
3-{[2-(4-Methylphenyl)-1,3-thiazolidin-3-yl]carbonyl}chromen-2-one chemical structure, C20H17NO3S, CAS 537677-89-7
3-{[2-(4-Methylphenyl)-1,3-thiazolidin-3-yl]carbonyl}chromen-2-one
CAS 537677-89-7C20H17NO3S
3-{[2-(3-Chlorophenyl)-1,3-thiazolidin-3-yl]carbonyl}-2H-chromen-2-one chemical structure, C19H14ClNO3S, CAS 313267-66-2
3-{[2-(3-Chlorophenyl)-1,3-thiazolidin-3-yl]carbonyl}-2H-chromen-2-one
CAS 313267-66-2C19H14ClNO3S
6-Bromo-3-(2-(2,5-dimethoxyphenyl)thiazolidine-3-carbonyl)-2H-chromen-2-one chemical structure, C21H18BrNO5S, CAS 421569-56-4
6-Bromo-3-(2-(2,5-dimethoxyphenyl)thiazolidine-3-carbonyl)-2H-chromen-2-one
CAS 421569-56-4C21H18BrNO5S
6,8-Dibromo-3-(2-(2,5-dimethoxyphenyl)thiazolidine-3-carbonyl)-2H-chromen-2-one chemical structure, C21H17Br2NO5S, CAS 421569-57-5
6,8-Dibromo-3-(2-(2,5-dimethoxyphenyl)thiazolidine-3-carbonyl)-2H-chromen-2-one
CAS 421569-57-5C21H17Br2NO5S
3-(2-(2,5-Dimethoxyphenyl)thiazolidine-3-carbonyl)-2H-chromen-2-one chemical structure, C21H19NO5S, CAS 402946-97-8
3-(2-(2,5-Dimethoxyphenyl)thiazolidine-3-carbonyl)-2H-chromen-2-one
CAS 402946-97-8C21H19NO5S
6,8-Dibromo-3-(2-(4-methoxyphenyl)thiazolidine-3-carbonyl)-2H-chromen-2-one chemical structure, C20H15Br2NO4S, CAS 313266-98-7
6,8-Dibromo-3-(2-(4-methoxyphenyl)thiazolidine-3-carbonyl)-2H-chromen-2-one
CAS 313266-98-7C20H15Br2NO4S
3-[2-(2-Methoxyphenyl)-1,3-thiazolidine-3-carbonyl]chromen-2-one chemical structure, C20H17NO4S, CAS 6192-34-3
3-[2-(2-Methoxyphenyl)-1,3-thiazolidine-3-carbonyl]chromen-2-one
CAS 6192-34-3C20H17NO4S