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Murcko scaffold

Ring system with 4 rings and 20 atoms

22 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
20
Chemicals
22
With full pages
2
Scaffold SMILES

O=C1CN2CCc3ccccc3C2c2ccccc2N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1CN2CCc3ccccc3C2c2ccccc2N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 22 of 22 chemicals

Clazolam chemical structure, C18H17ClN2O, CAS 7492-29-7
Clazolam
CAS 7492-29-7C18H17ClN2O
Isoquino(2,1-d)(1,4)benzodiazepin-6(7H)-one, 5,9,10,14b-tetrahydro-2-chloro-5-ethyl- chemical structure, C19H19ClN2O, CAS 10159-05-4
Isoquino(2,1-d)(1,4)benzodiazepin-6(7H)-one, 5,9,10,14b-tetrahydro-2-chloro-5-ethyl-
CAS 10159-05-4C19H19ClN2O
Isoquino(2,1-d)(1,4)benzodiazepin-6(7H)-one, 5,9,10,14b-tetrahydro-5-methyl-2-(trifluoromethyl)- chemical structure, C19H17F3N2O, CAS 10243-44-4
Isoquino(2,1-d)(1,4)benzodiazepin-6(7H)-one, 5,9,10,14b-tetrahydro-5-methyl-2-(trifluoromethyl)-
CAS 10243-44-4C19H17F3N2O
Isoquino(2,1-d)(1,4)benzodiazepin-6(7H)-one, 5,9,10,14b-tetrahydro-2-chloro-5-(3-(dimethylamino)propyl)- chemical structure, C22H26ClN3O, CAS 10256-71-0
Isoquino(2,1-d)(1,4)benzodiazepin-6(7H)-one, 5,9,10,14b-tetrahydro-2-chloro-5-(3-(dimethylamino)propyl)-
CAS 10256-71-0C22H26ClN3O
Isoquino(2,1-d)(1,4)benzodiazepin-6(7H)-one, 5,9,10,14b-tetrahydro-2-nitro- chemical structure, C17H15N3O3, CAS 17617-18-4
Isoquino(2,1-d)(1,4)benzodiazepin-6(7H)-one, 5,9,10,14b-tetrahydro-2-nitro-
CAS 17617-18-4C17H15N3O3
Isoquino(2,1-d)(1,4)benzodiazepin-6(7H)-one, 5,9,10,14b-tetrahydro-5,10,10-trimethyl- chemical structure, C20H22N2O, CAS 17656-71-2
Isoquino(2,1-d)(1,4)benzodiazepin-6(7H)-one, 5,9,10,14b-tetrahydro-5,10,10-trimethyl-
CAS 17656-71-2C20H22N2O
Isoquino(2,1-d)(1,4)benzodiazepin-6(7H)-one, 5,9,10,14b-tetrahydro-2-bromo-5-methyl- chemical structure, C18H17BrN2O, CAS 19007-20-6
Isoquino(2,1-d)(1,4)benzodiazepin-6(7H)-one, 5,9,10,14b-tetrahydro-2-bromo-5-methyl-
CAS 19007-20-6C18H17BrN2O
Isoquino(2,1-d)(1,4)benzodiazepin-6(7H)-one, 5,9,10,14b-tetrahydro-12,13-dimethoxy- chemical structure, C19H20N2O3, CAS 41334-70-7
Isoquino(2,1-d)(1,4)benzodiazepin-6(7H)-one, 5,9,10,14b-tetrahydro-12,13-dimethoxy-
CAS 41334-70-7C19H20N2O3
Isoquino(2,1-d)(1,4)benzodiazepin-6(7H)-one, 5,9,10,14b-tetrahydro-12,13-dimethoxy-7-methyl- chemical structure, C20H22N2O3, CAS 41334-72-9
Isoquino(2,1-d)(1,4)benzodiazepin-6(7H)-one, 5,9,10,14b-tetrahydro-12,13-dimethoxy-7-methyl-
CAS 41334-72-9C20H22N2O3
Isoquino(2,1-d)(1,4)benzodiazepin-6(7H)-one, 5,9,10,14b-tetrahydro-12,13-dimethoxy-7-ethyl- chemical structure, C21H24N2O3, CAS 54971-42-5
Isoquino(2,1-d)(1,4)benzodiazepin-6(7H)-one, 5,9,10,14b-tetrahydro-12,13-dimethoxy-7-ethyl-
CAS 54971-42-5C21H24N2O3
Isoquino(2,1-d)(1,4)benzodiazepin-6(7H)-one, 5,9,10,14b-tetrahydro-2-chloro-5(hydroxymethyl)-, acetate (ester) chemical structure, C20H19ClN2O3, CAS 67239-20-7
Isoquino(2,1-d)(1,4)benzodiazepin-6(7H)-one, 5,9,10,14b-tetrahydro-2-chloro-5(hydroxymethyl)-, acetate (ester)
CAS 67239-20-7C20H19ClN2O3
Isoquino(2,1-d)(1,4)benzodiazepin-6(7H)-one, 5,9,10,14b-tetrahydro-5-methyl- chemical structure, C18H18N2O, CAS 67239-22-9
Isoquino(2,1-d)(1,4)benzodiazepin-6(7H)-one, 5,9,10,14b-tetrahydro-5-methyl-
CAS 67239-22-9C18H18N2O
Isoquino(2,1-d)(1,4)benzodiazepin-6(7H)-one, 5,9,10,14b-tetrahydro-11-amino-12,13-dimethoxy- chemical structure, C19H21N3O3, CAS 75230-89-6
Isoquino(2,1-d)(1,4)benzodiazepin-6(7H)-one, 5,9,10,14b-tetrahydro-11-amino-12,13-dimethoxy-
CAS 75230-89-6C19H21N3O3
Isoquino(2,1-d)(1,4)benzodiazepin-6(7H)-one, 5,9,10,14b-tetrahydro-12,13-dimethoxy-7-isopropyl- chemical structure, C22H26N2O3, CAS 75230-92-1
Isoquino(2,1-d)(1,4)benzodiazepin-6(7H)-one, 5,9,10,14b-tetrahydro-12,13-dimethoxy-7-isopropyl-
CAS 75230-92-1C22H26N2O3
Isoquino(2,1-d)(1,4)benzodiazepin-6(7H)-one, 5,9,10,14b-tetrahydro-3-chloro-12,13-dimethoxy- chemical structure, C19H19ClN2O3, CAS 82802-88-8
Isoquino(2,1-d)(1,4)benzodiazepin-6(7H)-one, 5,9,10,14b-tetrahydro-3-chloro-12,13-dimethoxy-
CAS 82802-88-8C19H19ClN2O3
Isoquino(2,1-d)(1,4)benzodiazepin-6(7H)-one, 5,9,10,14b-tetrahydro-2-chloro-12,13-dimethoxy-7-ethyl- chemical structure, C21H23ClN2O3, CAS 102395-73-3
Isoquino(2,1-d)(1,4)benzodiazepin-6(7H)-one, 5,9,10,14b-tetrahydro-2-chloro-12,13-dimethoxy-7-ethyl-
CAS 102395-73-3C21H23ClN2O3
Isoquino(2,1-d)(1,4)benzodiazepin-6(7H)-one, 5,9,10,14b-tetrahydro-12,13-dimethoxy-10-nitro chemical structure, C19H19N3O5, CAS 102395-74-4
Isoquino(2,1-d)(1,4)benzodiazepin-6(7H)-one, 5,9,10,14b-tetrahydro-12,13-dimethoxy-10-nitro
CAS 102395-74-4C19H19N3O5
Isoquino(2,1-d)(1,4)benzodiazepin-6(7H)-one, 5,9,10,14b-tetrahydro-5-allyl-2-chloro- chemical structure, C20H19ClN2O, CAS 10256-57-2
Isoquino(2,1-d)(1,4)benzodiazepin-6(7H)-one, 5,9,10,14b-tetrahydro-5-allyl-2-chloro-
CAS 10256-57-2C20H19ClN2O
Isoquino(2,1-d)(1,4)benzodiazepin-6(7H)-one, 5,9,10,14b-tetrahydro-2-chloro-5-propyl- chemical structure, C20H21ClN2O, CAS 10256-58-3
Isoquino(2,1-d)(1,4)benzodiazepin-6(7H)-one, 5,9,10,14b-tetrahydro-2-chloro-5-propyl-
CAS 10256-58-3C20H21ClN2O
Isoquino(2,1-d)(1,4)benzodiazepin-6(7H)-one, 5,9,10,14b-tetrahydro-5-methyl-2-nitro- chemical structure, C18H17N3O3, CAS 19007-22-8
Isoquino(2,1-d)(1,4)benzodiazepin-6(7H)-one, 5,9,10,14b-tetrahydro-5-methyl-2-nitro-
CAS 19007-22-8C18H17N3O3
Isoquino(2,1-d)(1,4)benzodiazepine-5(9H)-acetamide, 6,7,10,14b-tetrahydro-2-chloro-N-methyl-6-oxo- chemical structure, C20H20ClN3O2, CAS 19007-30-8
Isoquino(2,1-d)(1,4)benzodiazepine-5(9H)-acetamide, 6,7,10,14b-tetrahydro-2-chloro-N-methyl-6-oxo-
CAS 19007-30-8C20H20ClN3O2
Clazolam hydrochloride chemical structure, C18H18Cl2N2O, CAS 23193-67-1
Clazolam hydrochloride
CAS 23193-67-1C18H18Cl2N2O