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Murcko scaffold

Ring system with 3 rings and 21 atoms

16 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
16
With full pages
6
Scaffold SMILES

O=C(NN=Cc1ccccc1)c1sccc1-n1cccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NN=Cc1ccccc1)c1sccc1-n1cccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 16 of 16 chemicals

N-[(4-Chlorophenyl)methylideneamino]-3-pyrrol-1-ylthiophene-2-carboxamide chemical structure, C16H12ClN3OS
N-[(4-Chlorophenyl)methylideneamino]-3-pyrrol-1-ylthiophene-2-carboxamide
C16H12ClN3OS
N-[(3-Methylphenyl)methylideneamino]-3-pyrrol-1-ylthiophene-2-carboxamide chemical structure, C17H15N3OS
N-[(3-Methylphenyl)methylideneamino]-3-pyrrol-1-ylthiophene-2-carboxamide
C17H15N3OS
N-[(2,4-Dichlorophenyl)methylideneamino]-3-pyrrol-1-ylthiophene-2-carboxamide chemical structure, C16H11Cl2N3OS
N-[(2,4-Dichlorophenyl)methylideneamino]-3-pyrrol-1-ylthiophene-2-carboxamide
C16H11Cl2N3OS
N'-[(Z)-Phenylmethylidene]-3-(1H-pyrrol-1-yl)-2-thiophenecarbohydrazide chemical structure, C16H13N3OS, CAS 478062-78-1
N'-[(Z)-Phenylmethylidene]-3-(1H-pyrrol-1-yl)-2-thiophenecarbohydrazide
CAS 478062-78-1C16H13N3OS
N'-[(Z)-(4-Chlorophenyl)methylidene]-3-(1H-pyrrol-1-yl)-2-thiophenecarbohydrazide chemical structure, C16H12ClN3OS, CAS 478062-83-8
N'-[(Z)-(4-Chlorophenyl)methylidene]-3-(1H-pyrrol-1-yl)-2-thiophenecarbohydrazide
CAS 478062-83-8C16H12ClN3OS
N'-[(Z)-(3-Methylphenyl)methylidene]-3-(1H-pyrrol-1-yl)-2-thiophenecarbohydrazide chemical structure, C17H15N3OS, CAS 478063-23-9
N'-[(Z)-(3-Methylphenyl)methylidene]-3-(1H-pyrrol-1-yl)-2-thiophenecarbohydrazide
CAS 478063-23-9C17H15N3OS
N'-[(Z)-(2,4-Dichlorophenyl)methylidene]-3-(1H-pyrrol-1-yl)-2-thiophenecarbohydrazide chemical structure, C16H11Cl2N3OS, CAS 478063-24-0
N'-[(Z)-(2,4-Dichlorophenyl)methylidene]-3-(1H-pyrrol-1-yl)-2-thiophenecarbohydrazide
CAS 478063-24-0C16H11Cl2N3OS
N-[(Z)-(2-Methylphenyl)methylideneamino]-3-pyrrol-1-ylthiophene-2-carboxamide chemical structure, C17H15N3OS, CAS 478076-85-6
N-[(Z)-(2-Methylphenyl)methylideneamino]-3-pyrrol-1-ylthiophene-2-carboxamide
CAS 478076-85-6C17H15N3OS
N-[(E)-1-(4-Chlorophenyl)ethylideneamino]-3-pyrrol-1-ylthiophene-2-carboxamide chemical structure, C17H14ClN3OS, CAS 478076-91-4
N-[(E)-1-(4-Chlorophenyl)ethylideneamino]-3-pyrrol-1-ylthiophene-2-carboxamide
CAS 478076-91-4C17H14ClN3OS
N'-[(E)-1-(4-Methoxyphenyl)ethylidene]-3-(1H-pyrrol-1-yl)-2-thiophenecarbohydrazide chemical structure, C18H17N3O2S, CAS 478076-92-5
N'-[(E)-1-(4-Methoxyphenyl)ethylidene]-3-(1H-pyrrol-1-yl)-2-thiophenecarbohydrazide
CAS 478076-92-5C18H17N3O2S
N-[(E)-(4-Methoxyphenyl)methylideneamino]-3-pyrrol-1-ylthiophene-2-carboxamide chemical structure, C17H15N3O2S, CAS 478076-90-3
N-[(E)-(4-Methoxyphenyl)methylideneamino]-3-pyrrol-1-ylthiophene-2-carboxamide
CAS 478076-90-3C17H15N3O2S
N'-{(E)-[4-(dimethylamino)phenyl]methylidene}-3-(1H-pyrrol-1-yl)-2-thiophenecarbohydrazide chemical structure, C18H18N4OS, CAS 478076-86-7
N'-{(E)-[4-(dimethylamino)phenyl]methylidene}-3-(1H-pyrrol-1-yl)-2-thiophenecarbohydrazide
CAS 478076-86-7C18H18N4OS
N-[(E)-(2,4-Dichlorophenyl)methylideneamino]-3-pyrrol-1-ylthiophene-2-carboxamide chemical structure, C16H11Cl2N3OS
N-[(E)-(2,4-Dichlorophenyl)methylideneamino]-3-pyrrol-1-ylthiophene-2-carboxamide
C16H11Cl2N3OS
3-(1H-Pyrrol-1-yl)-N'-{(E)-1-[3-(trifluoromethyl)phenyl]ethylidene}-2-thiophenecarbohydrazide chemical structure, C18H14F3N3OS, CAS 478076-93-6
3-(1H-Pyrrol-1-yl)-N'-{(E)-1-[3-(trifluoromethyl)phenyl]ethylidene}-2-thiophenecarbohydrazide
CAS 478076-93-6C18H14F3N3OS
N-[(E)-(4-Chlorophenyl)methylideneamino]-3-pyrrol-1-ylthiophene-2-carboxamide chemical structure, C16H12ClN3OS
N-[(E)-(4-Chlorophenyl)methylideneamino]-3-pyrrol-1-ylthiophene-2-carboxamide
C16H12ClN3OS
N-[(E)-(3-Methylphenyl)methylideneamino]-3-pyrrol-1-ylthiophene-2-carboxamide chemical structure, C17H15N3OS
N-[(E)-(3-Methylphenyl)methylideneamino]-3-pyrrol-1-ylthiophene-2-carboxamide
C17H15N3OS