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Murcko scaffold

Ring system with 4 rings and 24 atoms

5 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
24
Chemicals
5
With full pages
3
Scaffold SMILES

O=C(CCN1CCNCC1)N1c2ccccc2Sc2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CCN1CCNCC1)N1c2ccccc2Sc2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 5 of 5 chemicals

Ketone, 2-chlorophenothiazin-10-yl 2-(4-(2-hydroxyethyl)-1-piperazinyl)ethyl, dihydrochloride chemical structure, C21H26Cl3N3O2S, CAS 28747-82-2
Ketone, 2-chlorophenothiazin-10-yl 2-(4-(2-hydroxyethyl)-1-piperazinyl)ethyl, dihydrochloride
CAS 28747-82-2C21H26Cl3N3O2S
1-Propanone, 3-(4-(2-hydroxyethyl)piperazinyl)-1-(phenothiazin-10-yl)-, dihydrochloride chemical structure, C21H27Cl2N3O2S, CAS 29573-87-3
1-Propanone, 3-(4-(2-hydroxyethyl)piperazinyl)-1-(phenothiazin-10-yl)-, dihydrochloride
CAS 29573-87-3C21H27Cl2N3O2S
Ftorpropazine chemical structure, C22H24F3N3O2S, CAS 33414-36-7
Ftorpropazine
CAS 33414-36-7C22H24F3N3O2S
1-(2-Chloro-10H-phenothiazin-10-yl)-3-(4-methylpiperazin-1-yl)propan-1-one chemical structure, C20H22ClN3OS, CAS 19077-28-2
1-(2-Chloro-10H-phenothiazin-10-yl)-3-(4-methylpiperazin-1-yl)propan-1-one
CAS 19077-28-2C20H22ClN3OS
Ftormetazine chemical structure, C21H22F3N3OS, CAS 33414-30-1
Ftormetazine
CAS 33414-30-1C21H22F3N3OS