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Murcko scaffold

Ring system with 5 rings and 31 atoms

9 chemicals on CompoundList share this ring system.

Rings
5
Scaffold atoms
31
Chemicals
9
With full pages
4
Scaffold SMILES

O=C(c1ccccc1)c1cnc2cc3c(cc2c1S(=O)(=O)c1ccccc1)OCCO3

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(c1ccccc1)c1cnc2cc3c(cc2c1S(=O)(=O)c1ccccc1)OCCO3

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

(4-Ethylphenyl)(9-tosyl-2,3-dihydro-[1,4]dioxino[2,3-g]quinolin-8-yl)methanone chemical structure, C27H23NO5S, CAS 866812-98-8
(4-Ethylphenyl)(9-tosyl-2,3-dihydro-[1,4]dioxino[2,3-g]quinolin-8-yl)methanone
CAS 866812-98-8C27H23NO5S
9-(4-Chlorobenzenesulfonyl)-8-(4-ethylbenzoyl)-2H,3H-[1,4]dioxino[2,3-g]quinoline chemical structure, C26H20ClNO5S, CAS 866813-04-9
9-(4-Chlorobenzenesulfonyl)-8-(4-ethylbenzoyl)-2H,3H-[1,4]dioxino[2,3-g]quinoline
CAS 866813-04-9C26H20ClNO5S
8-(4-Ethylbenzoyl)-9-(4-fluorobenzenesulfonyl)-2H,3H-[1,4]dioxino[2,3-g]quinoline chemical structure, C26H20FNO5S, CAS 872199-35-4
8-(4-Ethylbenzoyl)-9-(4-fluorobenzenesulfonyl)-2H,3H-[1,4]dioxino[2,3-g]quinoline
CAS 872199-35-4C26H20FNO5S
8-Benzoyl-9-(4-methylbenzenesulfonyl)-2H,3H-[1,4]dioxino[2,3-g]quinoline chemical structure, C25H19NO5S, CAS 866895-52-5
8-Benzoyl-9-(4-methylbenzenesulfonyl)-2H,3H-[1,4]dioxino[2,3-g]quinoline
CAS 866895-52-5C25H19NO5S
8-Benzoyl-9-(3,4-dimethylbenzenesulfonyl)-2H,3H-[1,4]dioxino[2,3-g]quinoline chemical structure, C26H21NO5S, CAS 866895-63-8
8-Benzoyl-9-(3,4-dimethylbenzenesulfonyl)-2H,3H-[1,4]dioxino[2,3-g]quinoline
CAS 866895-63-8C26H21NO5S
8-Benzoyl-9-(4-ethoxybenzenesulfonyl)-2H,3H-[1,4]dioxino[2,3-g]quinoline chemical structure, C26H21NO6S, CAS 866895-78-5
8-Benzoyl-9-(4-ethoxybenzenesulfonyl)-2H,3H-[1,4]dioxino[2,3-g]quinoline
CAS 866895-78-5C26H21NO6S
[9-(4-Ethoxyphenyl)sulfonyl-2,3-dihydro-[1,4]dioxino[2,3-g]quinolin-8-yl]-(4-methylphenyl)methanone chemical structure, C27H23NO6S, CAS 866895-82-1
[9-(4-Ethoxyphenyl)sulfonyl-2,3-dihydro-[1,4]dioxino[2,3-g]quinolin-8-yl]-(4-methylphenyl)methanone
CAS 866895-82-1C27H23NO6S
8-Benzoyl-9-(4-ethylbenzenesulfonyl)-2H,3H-[1,4]dioxino[2,3-g]quinoline chemical structure, C26H21NO5S, CAS 899760-28-2
8-Benzoyl-9-(4-ethylbenzenesulfonyl)-2H,3H-[1,4]dioxino[2,3-g]quinoline
CAS 899760-28-2C26H21NO5S
[9-(Benzenesulfonyl)-2,3-dihydro-[1,4]dioxino[2,3-g]quinolin-8-yl]-(4-methylphenyl)methanone chemical structure, C25H19NO5S, CAS 866845-29-6
[9-(Benzenesulfonyl)-2,3-dihydro-[1,4]dioxino[2,3-g]quinolin-8-yl]-(4-methylphenyl)methanone
CAS 866845-29-6C25H19NO5S