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Murcko scaffold

2,5-Dihydro-1H-pyrrol-2-one scaffold

260 chemicals on CompoundList share this ring system.

Rings
1
Scaffold atoms
6
Chemicals
260
With full pages
29
Scaffold SMILES

O=C1C=CCN1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.

Substructure search with this scaffoldOpen the 2,5-Dihydro-1H-pyrrol-2-one page
Murcko scaffold O=C1C=CCN1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 260 chemicals

3-Acetyl-5-hydroxy-4,5-dimethyl-1-octyl-2-pyrrolone chemical structure, C16H27NO3, CAS 186379-49-7
3-Acetyl-5-hydroxy-4,5-dimethyl-1-octyl-2-pyrrolone
CAS 186379-49-7C16H27NO3
3-Acetyl-4,5-dimethyl-5-hydroxy-1,5-dihydro-2H-pyrrol-2-one chemical structure, C8H11NO3, CAS 98593-79-4
3-Acetyl-4,5-dimethyl-5-hydroxy-1,5-dihydro-2H-pyrrol-2-one
CAS 98593-79-4C8H11NO3
2-Hydroxyhemopyrroline-5-one chemical structure, C8H13NO2, CAS 53573-42-5
2-Hydroxyhemopyrroline-5-one
CAS 53573-42-5C8H13NO2
5-Hydroxykryptopyrrolin-2-one chemical structure, C8H13NO2, CAS 41254-89-1
5-Hydroxykryptopyrrolin-2-one
CAS 41254-89-1C8H13NO2
5-Hydroxy-4-methyl-2,5-dihydro-1H-pyrrol-2-one chemical structure, C5H7NO2, CAS 79641-88-6
5-Hydroxy-4-methyl-2,5-dihydro-1H-pyrrol-2-one
CAS 79641-88-6C5H7NO2
RefChem:357332 chemical structure, C7H8N2O2, CAS 29810-81-9
RefChem:357332
CAS 29810-81-9C7H8N2O2
(R)-Dihydromaleimide chemical structure, C4H5NO2, CAS 87710-47-2
(R)-Dihydromaleimide
CAS 87710-47-2C4H5NO2
2H-Pyrrol-2-one, 1,5-dihydro-1-methyl- chemical structure, C5H7NO, CAS 13950-21-5
2H-Pyrrol-2-one, 1,5-dihydro-1-methyl-
CAS 13950-21-5C5H7NO
5-Methoxy-3,5-dimethyl-1H-pyrrol-2-one chemical structure, C7H11NO2, CAS 13917-74-3
5-Methoxy-3,5-dimethyl-1H-pyrrol-2-one
CAS 13917-74-3C7H11NO2
3,4-Dimethyl-1,5-dihydro-(2H)-pyrrol-2-one chemical structure, C6H9NO, CAS 4030-22-2
3,4-Dimethyl-1,5-dihydro-(2H)-pyrrol-2-one
CAS 4030-22-2C6H9NO
4-Methoxy-2,5-dihydro-1H-pyrrol-2-one chemical structure, C5H7NO2, CAS 69778-83-2
4-Methoxy-2,5-dihydro-1H-pyrrol-2-one
CAS 69778-83-2C5H7NO2
3-Pyrrolin-2-one, 4-ethoxy-1-(2-propynyl)- chemical structure, C9H11NO2, CAS 671183-67-8
3-Pyrrolin-2-one, 4-ethoxy-1-(2-propynyl)-
CAS 671183-67-8C9H11NO2
2,5-Dihydro-1H-pyrrol-2-one chemical structure, C4H5NO, CAS 4031-15-6
2,5-Dihydro-1H-pyrrol-2-one
CAS 4031-15-6C4H5NO
Ethyl 4-amino-1-methyl-5-oxo-2,5-dihydro-1H-pyrrole-3-carboxylate chemical structure, C8H12N2O3, CAS 329695-21-8
Ethyl 4-amino-1-methyl-5-oxo-2,5-dihydro-1H-pyrrole-3-carboxylate
CAS 329695-21-8C8H12N2O3
Ethyl 1-(dimethylamino)-2,5-dihydro-4-[(1-methylethyl)amino]-5-oxo-1H-pyrrole-3-carboxylate chemical structure, C12H21N3O3, CAS 329698-62-6
Ethyl 1-(dimethylamino)-2,5-dihydro-4-[(1-methylethyl)amino]-5-oxo-1H-pyrrole-3-carboxylate
CAS 329698-62-6C12H21N3O3
1,5-Dihydro-3-ethyl-4-methyl-2H-pyrrol-2-one chemical structure, C7H11NO, CAS 766-36-9
1,5-Dihydro-3-ethyl-4-methyl-2H-pyrrol-2-one
CAS 766-36-9C7H11NO
4-Ethoxy-3-methyl-2,5-dihydro-1H-pyrrol-2-one chemical structure, C7H11NO2, CAS 246147-55-7
4-Ethoxy-3-methyl-2,5-dihydro-1H-pyrrol-2-one
CAS 246147-55-7C7H11NO2
1-Acetyl-4-methyl-2,5-dihydro-1H-pyrrol-2-one chemical structure, C7H9NO2, CAS 34581-92-5
1-Acetyl-4-methyl-2,5-dihydro-1H-pyrrol-2-one
CAS 34581-92-5C7H9NO2
Dimethyl 4-amino-2-(2-methoxy-2-oxoethyl)-5-oxo-2,5-dihydro-1H-pyrrole-2,3-dicarboxylate chemical structure, C11H14N2O7, CAS 141625-43-6
Dimethyl 4-amino-2-(2-methoxy-2-oxoethyl)-5-oxo-2,5-dihydro-1H-pyrrole-2,3-dicarboxylate
CAS 141625-43-6C11H14N2O7
3-Acetyl-1-dodecyl-1,5-dihydro-5-hydroxy-4,5-dimethyl-2H-Pyrrol-2-one chemical structure, C20H35NO3, CAS 186379-51-1
3-Acetyl-1-dodecyl-1,5-dihydro-5-hydroxy-4,5-dimethyl-2H-Pyrrol-2-one
CAS 186379-51-1C20H35NO3
3-Pyrrolin-2-one, 4-hydroxy-3-methyl-, ammonium salt chemical structure, C5H10N2O2, CAS 78308-53-9
3-Pyrrolin-2-one, 4-hydroxy-3-methyl-, ammonium salt
CAS 78308-53-9C5H10N2O2
Jatropham chemical structure, C5H7NO2, CAS 50656-76-3
Jatropham
CAS 50656-76-3C5H7NO2
3-Acetyl-1-hexadecyl-1,5-dihydro-5-hydroxy-4,5-dimethyl-2H-pyrrol-2-one chemical structure, C24H43NO3, CAS 186379-53-3
3-Acetyl-1-hexadecyl-1,5-dihydro-5-hydroxy-4,5-dimethyl-2H-pyrrol-2-one
CAS 186379-53-3C24H43NO3
2H-Pyrrol-2-one, 4-ethyl-1,5-dihydro-3-methyl- chemical structure, C7H11NO, CAS 766-45-0
2H-Pyrrol-2-one, 4-ethyl-1,5-dihydro-3-methyl-
CAS 766-45-0C7H11NO