CompoundList
Sign in
Murcko scaffold

N-[2-(2H-1,3-Benzodioxol-5-yl)-2-(morpholin-4-yl)ethyl]-N'-phenylethanediamide scaffold

11 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
29
Chemicals
11
With full pages
2
Scaffold SMILES

O=C(NCC(c1ccc2c(c1)OCO2)N1CCOCC1)C(=O)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-[2-(2H-1,3-Benzodioxol-5-yl)-2-(morpholin-4-yl)ethyl]-N'-phenylethanediamide page
Murcko scaffold O=C(NCC(c1ccc2c(c1)OCO2)N1CCOCC1)C(=O)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 11 of 11 chemicals

N-[2-(2H-1,3-Benzodioxol-5-yl)-2-(morpholin-4-yl)ethyl]-N'-(4-ethylphenyl)ethanediamide chemical structure, C23H27N3O5, CAS 887218-24-8
N-[2-(2H-1,3-Benzodioxol-5-yl)-2-(morpholin-4-yl)ethyl]-N'-(4-ethylphenyl)ethanediamide
CAS 887218-24-8C23H27N3O5
N-[2-(2H-1,3-Benzodioxol-5-yl)-2-(morpholin-4-yl)ethyl]-N'-phenylethanediamide chemical structure, C21H23N3O5, CAS 887218-36-2
N-[2-(2H-1,3-Benzodioxol-5-yl)-2-(morpholin-4-yl)ethyl]-N'-phenylethanediamide
CAS 887218-36-2C21H23N3O5
N-[2-(2H-1,3-Benzodioxol-5-yl)-2-(morpholin-4-yl)ethyl]-N'-(3-chlorophenyl)ethanediamide chemical structure, C21H22ClN3O5, CAS 896371-32-7
N-[2-(2H-1,3-Benzodioxol-5-yl)-2-(morpholin-4-yl)ethyl]-N'-(3-chlorophenyl)ethanediamide
CAS 896371-32-7C21H22ClN3O5
N1-(2-(benzo[d][1,3]dioxol-5-yl)-2-morpholinoethyl)-N2-(3,5-dimethylphenyl)oxalamide chemical structure, C23H27N3O5, CAS 896371-41-8
N1-(2-(benzo[d][1,3]dioxol-5-yl)-2-morpholinoethyl)-N2-(3,5-dimethylphenyl)oxalamide
CAS 896371-41-8C23H27N3O5
N1-(2-(benzo[d][1,3]dioxol-5-yl)-2-morpholinoethyl)-N2-(2,4-difluorophenyl)oxalamide chemical structure, C21H21F2N3O5, CAS 887217-90-5
N1-(2-(benzo[d][1,3]dioxol-5-yl)-2-morpholinoethyl)-N2-(2,4-difluorophenyl)oxalamide
CAS 887217-90-5C21H21F2N3O5
N-[2-(2H-1,3-Benzodioxol-5-yl)-2-(morpholin-4-yl)ethyl]-N'-(4-chlorophenyl)ethanediamide chemical structure, C21H22ClN3O5, CAS 887217-35-8
N-[2-(2H-1,3-Benzodioxol-5-yl)-2-(morpholin-4-yl)ethyl]-N'-(4-chlorophenyl)ethanediamide
CAS 887217-35-8C21H22ClN3O5
N1-(2-(benzo[d][1,3]dioxol-5-yl)-2-morpholinoethyl)-N2-(p-tolyl)oxalamide chemical structure, C22H25N3O5, CAS 887217-39-2
N1-(2-(benzo[d][1,3]dioxol-5-yl)-2-morpholinoethyl)-N2-(p-tolyl)oxalamide
CAS 887217-39-2C22H25N3O5
N-[2-(2H-1,3-Benzodioxol-5-yl)-2-(morpholin-4-yl)ethyl]-N'-(2-fluorophenyl)ethanediamide chemical structure, C21H22FN3O5, CAS 887217-87-0
N-[2-(2H-1,3-Benzodioxol-5-yl)-2-(morpholin-4-yl)ethyl]-N'-(2-fluorophenyl)ethanediamide
CAS 887217-87-0C21H22FN3O5
N-[2-(2H-1,3-Benzodioxol-5-yl)-2-(morpholin-4-yl)ethyl]-N'-(4-fluorophenyl)ethanediamide chemical structure, C21H22FN3O5, CAS 887217-93-8
N-[2-(2H-1,3-Benzodioxol-5-yl)-2-(morpholin-4-yl)ethyl]-N'-(4-fluorophenyl)ethanediamide
CAS 887217-93-8C21H22FN3O5
N-[2-(2H-1,3-Benzodioxol-5-yl)-2-(morpholin-4-yl)ethyl]-N'-(2-chlorophenyl)ethanediamide chemical structure, C21H22ClN3O5, CAS 887218-56-6
N-[2-(2H-1,3-Benzodioxol-5-yl)-2-(morpholin-4-yl)ethyl]-N'-(2-chlorophenyl)ethanediamide
CAS 887218-56-6C21H22ClN3O5
N'-[2-(2H-1,3-Benzodioxol-5-yl)-2-(morpholin-4-yl)ethyl]-N-(2,5-dimethylphenyl)ethanediamide chemical structure, C23H27N3O5, CAS 887218-63-5
N'-[2-(2H-1,3-Benzodioxol-5-yl)-2-(morpholin-4-yl)ethyl]-N-(2,5-dimethylphenyl)ethanediamide
CAS 887218-63-5C23H27N3O5