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Murcko scaffold

Ring system with 4 rings and 29 atoms

13 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
29
Chemicals
13
With full pages
6
Scaffold SMILES

O=C(NCC(c1ccc2c(c1)OCO2)N1CCNCC1)C(=O)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NCC(c1ccc2c(c1)OCO2)N1CCNCC1)C(=O)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 13 of 13 chemicals

N-[2-(1,3-Benzodioxol-5-yl)-2-(4-methylpiperazin-1-yl)ethyl]-N'-(3,5-dimethylphenyl)ethanediamide chemical structure, C24H30N4O4, CAS 896336-38-2
N-[2-(1,3-Benzodioxol-5-yl)-2-(4-methylpiperazin-1-yl)ethyl]-N'-(3,5-dimethylphenyl)ethanediamide
CAS 896336-38-2C24H30N4O4
N-[2-(2H-1,3-Benzodioxol-5-yl)-2-(4-methylpiperazin-1-yl)ethyl]-N'-(2,4-difluorophenyl)ethanediamide chemical structure, C22H24F2N4O4, CAS 896339-01-8
N-[2-(2H-1,3-Benzodioxol-5-yl)-2-(4-methylpiperazin-1-yl)ethyl]-N'-(2,4-difluorophenyl)ethanediamide
CAS 896339-01-8C22H24F2N4O4
N-[2-(1,3-Benzodioxol-5-yl)-2-(4-methylpiperazin-1-yl)ethyl]-N'-(3-methoxyphenyl)ethanediamide chemical structure, C23H28N4O5, CAS 896340-44-6
N-[2-(1,3-Benzodioxol-5-yl)-2-(4-methylpiperazin-1-yl)ethyl]-N'-(3-methoxyphenyl)ethanediamide
CAS 896340-44-6C23H28N4O5
N-[2-(2H-1,3-Benzodioxol-5-yl)-2-(4-methylpiperazin-1-yl)ethyl]-N'-(4-ethylphenyl)ethanediamide chemical structure, C24H30N4O4, CAS 896340-76-4
N-[2-(2H-1,3-Benzodioxol-5-yl)-2-(4-methylpiperazin-1-yl)ethyl]-N'-(4-ethylphenyl)ethanediamide
CAS 896340-76-4C24H30N4O4
N-[2-(2H-1,3-Benzodioxol-5-yl)-2-(4-methylpiperazin-1-yl)ethyl]-N'-(2,3-dimethylphenyl)ethanediamide chemical structure, C24H30N4O4, CAS 896342-43-1
N-[2-(2H-1,3-Benzodioxol-5-yl)-2-(4-methylpiperazin-1-yl)ethyl]-N'-(2,3-dimethylphenyl)ethanediamide
CAS 896342-43-1C24H30N4O4
N-[2-(1,3-Benzodioxol-5-yl)-2-(4-methylpiperazin-1-yl)ethyl]-N'-(2,6-dimethylphenyl)ethanediamide chemical structure, C24H30N4O4, CAS 896342-51-1
N-[2-(1,3-Benzodioxol-5-yl)-2-(4-methylpiperazin-1-yl)ethyl]-N'-(2,6-dimethylphenyl)ethanediamide
CAS 896342-51-1C24H30N4O4
N-[2-(2H-1,3-Benzodioxol-5-yl)-2-(4-methylpiperazin-1-yl)ethyl]-N'-(3,4-dimethylphenyl)ethanediamide chemical structure, C24H30N4O4, CAS 896343-15-0
N-[2-(2H-1,3-Benzodioxol-5-yl)-2-(4-methylpiperazin-1-yl)ethyl]-N'-(3,4-dimethylphenyl)ethanediamide
CAS 896343-15-0C24H30N4O4
N-[2-(2H-1,3-Benzodioxol-5-yl)-2-(4-methylpiperazin-1-yl)ethyl]-N'-(2,4-dimethylphenyl)ethanediamide chemical structure, C24H30N4O4, CAS 896343-23-0
N-[2-(2H-1,3-Benzodioxol-5-yl)-2-(4-methylpiperazin-1-yl)ethyl]-N'-(2,4-dimethylphenyl)ethanediamide
CAS 896343-23-0C24H30N4O4
N-[2-(2H-1,3-Benzodioxol-5-yl)-2-(4-methylpiperazin-1-yl)ethyl]-N'-(4-methylphenyl)ethanediamide chemical structure, C23H28N4O4, CAS 896335-76-5
N-[2-(2H-1,3-Benzodioxol-5-yl)-2-(4-methylpiperazin-1-yl)ethyl]-N'-(4-methylphenyl)ethanediamide
CAS 896335-76-5C23H28N4O4
N-[2-(2H-1,3-Benzodioxol-5-yl)-2-(4-methylpiperazin-1-yl)ethyl]-N'-(2-fluorophenyl)ethanediamide chemical structure, C22H25FN4O4, CAS 896338-93-5
N-[2-(2H-1,3-Benzodioxol-5-yl)-2-(4-methylpiperazin-1-yl)ethyl]-N'-(2-fluorophenyl)ethanediamide
CAS 896338-93-5C22H25FN4O4
N-[2-(2H-1,3-Benzodioxol-5-yl)-2-(4-methylpiperazin-1-yl)ethyl]-N'-(4-fluorophenyl)ethanediamide chemical structure, C22H25FN4O4, CAS 896339-09-6
N-[2-(2H-1,3-Benzodioxol-5-yl)-2-(4-methylpiperazin-1-yl)ethyl]-N'-(4-fluorophenyl)ethanediamide
CAS 896339-09-6C22H25FN4O4
N-[2-(2H-1,3-Benzodioxol-5-yl)-2-(4-methylpiperazin-1-yl)ethyl]-N'-(3-fluorophenyl)ethanediamide chemical structure, C22H25FN4O4, CAS 896339-17-6
N-[2-(2H-1,3-Benzodioxol-5-yl)-2-(4-methylpiperazin-1-yl)ethyl]-N'-(3-fluorophenyl)ethanediamide
CAS 896339-17-6C22H25FN4O4
N-[2-(2H-1,3-Benzodioxol-5-yl)-2-(4-methylpiperazin-1-yl)ethyl]-N'-(2,5-dimethylphenyl)ethanediamide chemical structure, C24H30N4O4, CAS 896343-31-0
N-[2-(2H-1,3-Benzodioxol-5-yl)-2-(4-methylpiperazin-1-yl)ethyl]-N'-(2,5-dimethylphenyl)ethanediamide
CAS 896343-31-0C24H30N4O4