Murcko scaffold
1H,6H,7H-Pyrrolo[2,3-c]pyridin-7-one scaffold
86 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 10
- Chemicals
- 86
- With full pages
- 9
Scaffold SMILES
O=c1[nH]ccc2cc[nH]c12
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
![Murcko scaffold O=c1[nH]ccc2cc[nH]c12](/scaffold/CIRNDJMEVJYOAW-UHFFFAOYSA-N/structure.svg)
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 86 chemicals
![6-Methyl-1,6-dihydro-7H-pyrrolo[2,3-c]pyridin-7-one chemical structure, C8H8N2O, CAS 116212-46-5](/s/ZLKWLYKVKAVOMD-UHFFFAOYSA-N.svg)
6-Methyl-1,6-dihydro-7H-pyrrolo[2,3-c]pyridin-7-one
CAS 116212-46-5C8H8N2O
![1H,6H,7H-Pyrrolo[2,3-c]pyridin-7-one chemical structure, C7H6N2O, CAS 259684-36-1](/s/CIRNDJMEVJYOAW-UHFFFAOYSA-N.svg)
1H,6H,7H-Pyrrolo[2,3-c]pyridin-7-one
CAS 259684-36-1C7H6N2O
![4-Methoxy-1H-pyrrolo[2,3-c]pyridin-7(6H)-one chemical structure, C8H8N2O2, CAS 917918-80-0](/s/KZKAJMZNTBJUNK-UHFFFAOYSA-N.svg)
4-Methoxy-1H-pyrrolo[2,3-c]pyridin-7(6H)-one
CAS 917918-80-0C8H8N2O2
![1,6-Dimethyl-1H,6H,7H-pyrrolo[2,3-c]pyridin-7-one chemical structure, C9H10N2O, CAS 1871808-35-3](/s/HKFFYZDSLSOEMD-UHFFFAOYSA-N.svg)
1,6-Dimethyl-1H,6H,7H-pyrrolo[2,3-c]pyridin-7-one
CAS 1871808-35-3C9H10N2O
![5-Amino-3-methyl-1H-pyrrolo[2,3-c]pyridin-7-ol chemical structure, C8H9N3O, CAS 502958-39-6](/s/JQNCDJZGVXNPGQ-UHFFFAOYSA-N.svg)
5-Amino-3-methyl-1H-pyrrolo[2,3-c]pyridin-7-ol
CAS 502958-39-6C8H9N3O
![1-Methyl-1H,6H,7H-pyrrolo[2,3-c]pyridin-7-one chemical structure, C8H8N2O, CAS 1311314-54-1](/s/MKLDTQZQFAGIBR-UHFFFAOYSA-N.svg)
1-Methyl-1H,6H,7H-pyrrolo[2,3-c]pyridin-7-one
CAS 1311314-54-1C8H8N2O
![1-Ethyl-1H,6H,7H-pyrrolo[2,3-c]pyridin-7-one chemical structure, C9H10N2O, CAS 1340902-81-9](/s/SETRUJSJLVLALL-UHFFFAOYSA-N.svg)
1-Ethyl-1H,6H,7H-pyrrolo[2,3-c]pyridin-7-one
CAS 1340902-81-9C9H10N2O
![1-(2-Methoxyethyl)-1,6-dihydro-7H-pyrrolo[2,3-c]pyridin-7-one chemical structure, C10H12N2O2, CAS 1340857-27-3](/s/MYYFEJCPCUFMDV-UHFFFAOYSA-N.svg)
1-(2-Methoxyethyl)-1,6-dihydro-7H-pyrrolo[2,3-c]pyridin-7-one
CAS 1340857-27-3C10H12N2O2
![1-(2-Dimethylaminoethyl)-6H-pyrrolo[2,3-c]pyridin-7-one chemical structure, C11H15N3O, CAS 1340814-15-4](/s/NNXGORDILQJIOB-UHFFFAOYSA-N.svg)
1-(2-Dimethylaminoethyl)-6H-pyrrolo[2,3-c]pyridin-7-one
CAS 1340814-15-4C11H15N3O
![1-Allyl-1,6-dihydro-7H-pyrrolo[2,3-c]pyridin-7-one chemical structure, C10H10N2O, CAS 1351399-15-9](/s/WGXYEGSWQDXYHR-UHFFFAOYSA-N.svg)
1-Allyl-1,6-dihydro-7H-pyrrolo[2,3-c]pyridin-7-one
CAS 1351399-15-9C10H10N2O
![3-Amino-1H-pyrrolo[2,3-c]pyridin-7-ol chemical structure, C7H7N3O, CAS 1190315-43-5](/s/ZWYGSPRXFKMCIF-UHFFFAOYSA-N.svg)
3-Amino-1H-pyrrolo[2,3-c]pyridin-7-ol
CAS 1190315-43-5C7H7N3O
![3-Bromo-1H-pyrrolo[2,3-c]pyridin-7-ol chemical structure, C7H5BrN2O, CAS 1190314-15-8](/s/XNKJNSPOKQILQB-UHFFFAOYSA-N.svg)
3-Bromo-1H-pyrrolo[2,3-c]pyridin-7-ol
CAS 1190314-15-8C7H5BrN2O
![3-Chloro-1H-pyrrolo[2,3-c]pyridin-7-ol chemical structure, C7H5ClN2O, CAS 1190314-08-9](/s/KVWUZSGRGQCYRH-UHFFFAOYSA-N.svg)
3-Chloro-1H-pyrrolo[2,3-c]pyridin-7-ol
CAS 1190314-08-9C7H5ClN2O
![3-Iodo-1,6-dihydropyrrolo[2,3-c]pyridin-7-one chemical structure, C7H5IN2O, CAS 1190316-65-4](/s/PRKCNCBWIXJPTB-UHFFFAOYSA-N.svg)
3-Iodo-1,6-dihydropyrrolo[2,3-c]pyridin-7-one
CAS 1190316-65-4C7H5IN2O
![3-Nitro-1H-pyrrolo[2,3-c]pyridin-7-ol chemical structure, C7H5N3O3, CAS 1190322-25-8](/s/HCXYCLGJEZLZHF-UHFFFAOYSA-N.svg)
3-Nitro-1H-pyrrolo[2,3-c]pyridin-7-ol
CAS 1190322-25-8C7H5N3O3
![7-Hydroxy-1H-pyrrolo[2,3-C]pyridine-3-carboxylic acid chemical structure, C8H6N2O3, CAS 1190317-24-8](/s/DQWAJFZLENIDQE-UHFFFAOYSA-N.svg)
7-Hydroxy-1H-pyrrolo[2,3-C]pyridine-3-carboxylic acid
CAS 1190317-24-8C8H6N2O3
![5-Methyl-1H,6H,7H-pyrrolo[2,3-c]pyridin-7-one chemical structure, C8H8N2O, CAS 1354951-02-2](/s/YNCVOFVJUZQLFT-UHFFFAOYSA-N.svg)
5-Methyl-1H,6H,7H-pyrrolo[2,3-c]pyridin-7-one
CAS 1354951-02-2C8H8N2O
![1,5-Dimethyl-1H,6H,7H-pyrrolo[2,3-c]pyridin-7-one chemical structure, C9H10N2O, CAS 1354951-04-4](/s/BLBXUYONYDHBAA-UHFFFAOYSA-N.svg)
1,5-Dimethyl-1H,6H,7H-pyrrolo[2,3-c]pyridin-7-one
CAS 1354951-04-4C9H10N2O
![4-Bromo-6-methyl-1H,6H,7H-pyrrolo[2,3-c]pyridin-7-one chemical structure, C8H7BrN2O, CAS 1361481-63-1](/s/SGOWUUBRFPHUIG-UHFFFAOYSA-N.svg)
4-Bromo-6-methyl-1H,6H,7H-pyrrolo[2,3-c]pyridin-7-one
CAS 1361481-63-1C8H7BrN2O
![7-Hydroxy-1H-pyrrolo[2,3-c]pyridine-3-carboxylic acid methyl ester chemical structure, C9H8N2O3, CAS 1313267-12-7](/s/VPXDDHVKFOKJTK-UHFFFAOYSA-N.svg)
7-Hydroxy-1H-pyrrolo[2,3-c]pyridine-3-carboxylic acid methyl ester
CAS 1313267-12-7C9H8N2O3
![7H-Pyrrolo[2,3-c]pyridin-7-one, 4-bromo-1,6-dihydro- chemical structure, C7H5BrN2O, CAS 1361481-62-0](/s/VRFVQTQXUMLFKV-UHFFFAOYSA-N.svg)
7H-Pyrrolo[2,3-c]pyridin-7-one, 4-bromo-1,6-dihydro-
CAS 1361481-62-0C7H5BrN2O
![3-Propyl-1H-pyrrolo[2,3-c]pyridin-7(6H)-one chemical structure, C10H12N2O, CAS 1493855-76-7](/s/FBRMNXPXKCONIR-UHFFFAOYSA-N.svg)
3-Propyl-1H-pyrrolo[2,3-c]pyridin-7(6H)-one
CAS 1493855-76-7C10H12N2O
![1,2-Dimethyl-1H,6H,7H-pyrrolo[2,3-c]pyridin-7-one chemical structure, C9H10N2O, CAS 1375471-39-8](/s/FNJBVDBVANKVKC-UHFFFAOYSA-N.svg)
1,2-Dimethyl-1H,6H,7H-pyrrolo[2,3-c]pyridin-7-one
CAS 1375471-39-8C9H10N2O
3-Bromo-1-methyl-1H,6H,7H-pyrrolo(2,3-c)pyridin-7-one
CAS 1375474-44-4C8H7BrN2O
- 4-Methyl-1,6-dihydropyrrolo[2,3-c]pyridin-7-one1934403-77-6C8H8N2O
- 2-Methyl-1H-pyrrolo[2,3-c]pyridin-7(6H)-one1427503-36-3C8H8N2O
- 6-Methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-C]pyridine-4-carboxylic acid1526955-38-3C9H8N2O3
- 2-Methyl-7-oxo-1,6-dihydropyrrolo[2,3-c]pyridine-4-carboxylic acid1513840-33-9C9H8N2O3
- 1,6-Dimethyl-7-oxo-pyrrolo[2,3-c]pyridine-4-carboxylic acid1539862-98-0C10H10N2O3
- 2,6-Dimethyl-7-oxo-1H-pyrrolo[2,3-c]pyridine-4-carboxylic acid1531204-33-7C10H10N2O3
- 2-Bromo-6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridine-4-carboxylic acid1782785-59-4C9H7BrN2O3
- 3-Bromo-6-methyl-1H-pyrrolo[2,3-c]pyridin-7-one1410974-52-5C8H7BrN2O
- tert-Butyl 7-oxo-1H,6H,7H-pyrrolo[2,3-c]pyridine-1-carboxylate1803590-95-5C12H14N2O3
- 7-Hydroxy-1H-pyrrolo[2,3-c]pyridine-3-carbaldehyde1190314-56-7C8H6N2O2
- 4-Bromo-1,6-dihydro-6-methyl-1-[[2-(trimethylsilyl)ethoxy]methyl]-7H-pyrrolo[2,3-c]pyridin-7-one1446236-70-9C14H21BrN2O2Si
- 2,6-Dimethyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridine-3-carboxylic acid1956327-94-8C10H10N2O3
- 4-Bromo-1-methyl-1H,6H,7H-pyrrolo[2,3-c]pyridin-7-one1815565-92-4C8H7BrN2O
- Ethyl 4-bromo-6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridine-2-carboxylate1622303-50-7C11H11BrN2O3
- 4-Bromo-6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridine-2-carboxylic acid1622303-52-9C9H7BrN2O3
- 4-Bromo-N-ethyl-6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridine-2-carboxamide1628864-79-8C11H12BrN3O2
- 4-Iodo-1H-pyrrolo[2,3-c]pyridin-7(6H)-one1956341-59-5C7H5IN2O
- 2,3,6-Trimethyl-1H-pyrrolo[2,3-c]pyridin-7(6H)-one1956335-58-2C10H12N2O
- 4-Bromo-2,3,6-trimethyl-1H-pyrrolo[2,3-c]pyridin-7(6H)-one1956379-66-0C10H11BrN2O
- 3,3,3-Trifluoro-N-(2-(1-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-6(7H)-yl)ethyl)propanamide2034378-81-7C13H14F3N3O2
- Ethyl 3-(3-(2-(1-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-6(7H)-yl)ethyl)ureido)propanoate2034460-66-5C16H22N4O4
- 6-{2-[(Dimethylsulfamoyl)amino]ethyl}-1-methyl-1H,6H,7H-pyrrolo[2,3-c]pyridin-7-one2034610-45-0C12H18N4O3S
- 2-Ethoxy-N-(2-(1-ethyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-6(7H)-yl)ethyl)acetamide2034559-45-8C15H21N3O3
- N-(2-{1-Ethyl-7-oxo-1H,6H,7H-pyrrolo[2,3-c]pyridin-6-yl}ethyl)methanesulfonamide2034551-99-8C12H17N3O3S
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