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Murcko scaffold

Ring system with 4 rings and 24 atoms

9 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
24
Chemicals
9
With full pages
3
Scaffold SMILES

O=C(OCc1ccccc1)N1CCCC1c1ncc2cnccn12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(OCc1ccccc1)N1CCCC1c1ncc2cnccn12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

FK3E7Ggy2J chemical structure, C18H18BrN5O2, CAS 2251014-90-9
FK3E7Ggy2J
CAS 2251014-90-9C18H18BrN5O2
(S)-Benzyl 2-(8-amino-1-bromoimidazo(1,5-a)pyrazin-3-yl)pyrrolidine-1-carboxylate chemical structure, C18H18BrN5O2, CAS 1420478-88-1
(S)-Benzyl 2-(8-amino-1-bromoimidazo(1,5-a)pyrazin-3-yl)pyrrolidine-1-carboxylate
CAS 1420478-88-1C18H18BrN5O2
(S)-Benzyl 2-(8-methylimidazo[1,5-a]pyrazin-3-yl)pyrrolidine-1-carboxylate chemical structure, C19H20N4O2, CAS 1418307-19-3
(S)-Benzyl 2-(8-methylimidazo[1,5-a]pyrazin-3-yl)pyrrolidine-1-carboxylate
CAS 1418307-19-3C19H20N4O2
(S)-Benzyl 2-(1-bromo-8-methylimidazo[1,5-a]pyrazin-3-yl)pyrrolidine-1-carboxylate chemical structure, C19H19BrN4O2, CAS 1418307-20-6
(S)-Benzyl 2-(1-bromo-8-methylimidazo[1,5-a]pyrazin-3-yl)pyrrolidine-1-carboxylate
CAS 1418307-20-6C19H19BrN4O2
Benzyl (2S)-2-{8-chloroimidazo[1,5-a]pyrazin-3-yl}pyrrolidine-1-carboxylate chemical structure, C18H17ClN4O2, CAS 1418307-18-2
Benzyl (2S)-2-{8-chloroimidazo[1,5-a]pyrazin-3-yl}pyrrolidine-1-carboxylate
CAS 1418307-18-2C18H17ClN4O2
1-Pyrrolidinecarboxylic acid, 2-(1-bromo-8-chloroimidazo(1,5-a)pyrazin-3-yl)-, phenylmethyl ester, (2S)- chemical structure, C18H16BrClN4O2, CAS 1420478-87-0
1-Pyrrolidinecarboxylic acid, 2-(1-bromo-8-chloroimidazo(1,5-a)pyrazin-3-yl)-, phenylmethyl ester, (2S)-
CAS 1420478-87-0C18H16BrClN4O2
(2R)-2-(8-Amino-1-bromoimidazo[1,5-a]pyrazin-3-yl)-1-pyrrolidinecarboxylic acid phenylmethyl ester chemical structure, C18H18BrN5O2, CAS 2198380-46-8
(2R)-2-(8-Amino-1-bromoimidazo[1,5-a]pyrazin-3-yl)-1-pyrrolidinecarboxylic acid phenylmethyl ester
CAS 2198380-46-8C18H18BrN5O2
Benzyl (S)-2-(8-amino-1-bromoimidazo[1,5-a]pyrazin-3-yl)pyrrolidine-1-carboxylate sulfate chemical structure, C18H20BrN5O6S, CAS 2097352-01-5
Benzyl (S)-2-(8-amino-1-bromoimidazo[1,5-a]pyrazin-3-yl)pyrrolidine-1-carboxylate sulfate
CAS 2097352-01-5C18H20BrN5O6S
Benzyl (S)-2-(8-aminoimidazo[1,5-A]pyrazin-3-yl)pyrrolidine-1-carboxylate chemical structure, C18H19N5O2, CAS 2170801-87-1
Benzyl (S)-2-(8-aminoimidazo[1,5-A]pyrazin-3-yl)pyrrolidine-1-carboxylate
CAS 2170801-87-1C18H19N5O2