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Murcko scaffold

Ring system with 4 rings and 25 atoms

6 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
25
Chemicals
6
With full pages
2
Scaffold SMILES

O=C(C=Cc1c(-c2ccccc2)nn2ccccc12)N1CCCCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(C=Cc1c(-c2ccccc2)nn2ccccc12)N1CCCCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

FK-453 chemical structure, C23H25N3O2, CAS 121524-18-3
FK-453
CAS 121524-18-3C23H25N3O2
FK-352 chemical structure, C23H23N3O3, CAS 143881-08-7
FK-352
CAS 143881-08-7C23H23N3O3
Wkr5EU6NQ3 chemical structure, C23H23N3O3, CAS 143955-46-8
Wkr5EU6NQ3
CAS 143955-46-8C23H23N3O3
2-Piperidineethanol, 1-[1-oxo-3-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)-2-propenyl]-, (E)- chemical structure, C23H25N3O2, CAS 121491-38-1
2-Piperidineethanol, 1-[1-oxo-3-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)-2-propenyl]-, (E)-
CAS 121491-38-1C23H25N3O2
1-[2-(2-Hydroxyethyl)piperidin-1-yl]-3-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)prop-2-en-1-one chemical structure, C23H25N3O2
1-[2-(2-Hydroxyethyl)piperidin-1-yl]-3-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)prop-2-en-1-one
C23H25N3O2
2-[(2S)-1-[(2E)-3-[2-Phenylpyrazolo[1,5-a]pyridin-3-yl]prop-2-enoyl]piperidin-2-yl]acetic acid chemical structure, C23H23N3O3, CAS 2743427-55-4
2-[(2S)-1-[(2E)-3-[2-Phenylpyrazolo[1,5-a]pyridin-3-yl]prop-2-enoyl]piperidin-2-yl]acetic acid
CAS 2743427-55-4C23H23N3O3