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Murcko scaffold

2-Phenyl-3,10-diazatricyclo[6.4.1.04,13]trideca-1,4,6,8(13)-tetraen-9-one scaffold

13 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
20
Chemicals
13
With full pages
3
Scaffold SMILES

O=C1NCCc2c(-c3ccccc3)[nH]c3cccc1c23

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Phenyl-3,10-diazatricyclo[6.4.1.04,13]trideca-1,4,6,8(13)-tetraen-9-one page
Murcko scaffold O=C1NCCc2c(-c3ccccc3)[nH]c3cccc1c23

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 13 of 13 chemicals

Rucaparib phosphate chemical structure, C19H21FN3O5P, CAS 459868-92-9
Rucaparib phosphate
CAS 459868-92-9C19H21FN3O5P
Rucaparib chemical structure, C19H18FN3O, CAS 283173-50-2
Rucaparib
CAS 283173-50-2C19H18FN3O
2-Phenyl-3,10-diazatricyclo[6.4.1.04,13]trideca-1,4,6,8(13)-tetraen-9-one chemical structure, C17H14N2O, CAS 283172-68-9
2-Phenyl-3,10-diazatricyclo[6.4.1.04,13]trideca-1,4,6,8(13)-tetraen-9-one
CAS 283172-68-9C17H14N2O
4-(8-Fluoro-3,4,5,6-tetrahydro-6-oxo-1H-pyrrolo(4,3,2-ef)(2)benzazepin-2-yl)benzaldehyde chemical structure, C18H13FN2O2, CAS 283173-84-2
4-(8-Fluoro-3,4,5,6-tetrahydro-6-oxo-1H-pyrrolo(4,3,2-ef)(2)benzazepin-2-yl)benzaldehyde
CAS 283173-84-2C18H13FN2O2
Methyl (4-(8-fluoro-1-oxo-2,3,4,6-tetrahydro-1H-azepino[5,4,3-cd]indol-5-yl)benzyl)(methyl)carbamate chemical structure, C21H20FN3O3, CAS 880160-69-0
Methyl (4-(8-fluoro-1-oxo-2,3,4,6-tetrahydro-1H-azepino[5,4,3-cd]indol-5-yl)benzyl)(methyl)carbamate
CAS 880160-69-0C21H20FN3O3
Rucaparib (hydrochloride) chemical structure, C19H19ClFN3O, CAS 773059-19-1
Rucaparib (hydrochloride)
CAS 773059-19-1C19H19ClFN3O
Rucaparib (acetate) chemical structure, C21H22FN3O3, CAS 773059-23-7
Rucaparib (acetate)
CAS 773059-23-7C21H22FN3O3
Rucaparib camsylate chemical structure, C29H34FN3O5S, CAS 1859053-21-6
Rucaparib camsylate
CAS 1859053-21-6C29H34FN3O5S
[(1R,4R)-7,7-Dimethyl-2-oxo-1-bicyclo[2.2.1]heptanyl]methanesulfonic acid, 6-fluoro-2-[4-(methylaminomethyl)phenyl]-3,10-diazatricyclo[6.4.1.04,13]trideca-1,4,6,8(13)-tetraen-9-one chemical structure, C29H34FN3O5S, CAS 1327258-57-0
[(1R,4R)-7,7-Dimethyl-2-oxo-1-bicyclo[2.2.1]heptanyl]methanesulfonic acid, 6-fluoro-2-[4-(methylaminomethyl)phenyl]-3,10-diazatricyclo[6.4.1.04,13]trideca-1,4,6,8(13)-tetraen-9-one
CAS 1327258-57-0C29H34FN3O5S
Rucaparib (tartrate) chemical structure, C23H24FN3O7, CAS 773059-22-6
Rucaparib (tartrate)
CAS 773059-22-6C23H24FN3O7
6H-Pyrrolo(4,3,2-ef)(2)benzazepin-6-one, 2-(4-(aminomethyl)phenyl)-8-fluoro-1,3,4,5-tetrahydro- chemical structure, C18H16FN3O, CAS 1577983-73-3
6H-Pyrrolo(4,3,2-ef)(2)benzazepin-6-one, 2-(4-(aminomethyl)phenyl)-8-fluoro-1,3,4,5-tetrahydro-
CAS 1577983-73-3C18H16FN3O
Benzoic acid, 4-(8-fluoro-3,4,5,6-tetrahydro-6-oxo-1H-pyrrolo(4,3,2-ef)(2)benzazepin-2-yl)- chemical structure, C18H13FN2O3, CAS 1577998-89-0
Benzoic acid, 4-(8-fluoro-3,4,5,6-tetrahydro-6-oxo-1H-pyrrolo(4,3,2-ef)(2)benzazepin-2-yl)-
CAS 1577998-89-0C18H13FN2O3
Rucaparib metabolite M337C chemical structure, C19H16FN3O2, CAS 1577999-02-0
Rucaparib metabolite M337C
CAS 1577999-02-0C19H16FN3O2