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Murcko scaffold

1,3-Diphenylimidazolidine-2,4-dione scaffold

35 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
35
With full pages
4
Scaffold SMILES

O=C1CN(c2ccccc2)C(=O)N1c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1,3-Diphenylimidazolidine-2,4-dione page
Murcko scaffold O=C1CN(c2ccccc2)C(=O)N1c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 35 of 35 chemicals

5-Acetyl-1,3-bis(4-bromophenyl)-5-methylimidazolidine-2,4-dione chemical structure, C18H14Br2N2O3, CAS 21631-64-1
5-Acetyl-1,3-bis(4-bromophenyl)-5-methylimidazolidine-2,4-dione
CAS 21631-64-1C18H14Br2N2O3
5-Acetyl-1,3-bis(4-fluorophenyl)-5-methylimidazolidine-2,4-dione chemical structure, C18H14F2N2O3, CAS 21631-62-9
5-Acetyl-1,3-bis(4-fluorophenyl)-5-methylimidazolidine-2,4-dione
CAS 21631-62-9C18H14F2N2O3
5-Acetyl-5-methyl-1,3-bis(4-nitrophenyl)imidazolidine-2,4-dione chemical structure, C18H14N4O7, CAS 21631-65-2
5-Acetyl-5-methyl-1,3-bis(4-nitrophenyl)imidazolidine-2,4-dione
CAS 21631-65-2C18H14N4O7
5-Acetyl-1,3-bis(4-chlorophenyl)-5-methylimidazolidine-2,4-dione chemical structure, C18H14Cl2N2O3, CAS 21631-63-0
5-Acetyl-1,3-bis(4-chlorophenyl)-5-methylimidazolidine-2,4-dione
CAS 21631-63-0C18H14Cl2N2O3
5-Acetyl-5-methyl-1,3-bis(4-methylphenyl)imidazolidine-2,4-dione chemical structure, C20H20N2O3, CAS 21631-66-3
5-Acetyl-5-methyl-1,3-bis(4-methylphenyl)imidazolidine-2,4-dione
CAS 21631-66-3C20H20N2O3
Ethyl 2,5-dioxo-1,3-diphenylimidazolidine-4-carboxylate chemical structure, C18H16N2O4, CAS 56598-97-1
Ethyl 2,5-dioxo-1,3-diphenylimidazolidine-4-carboxylate
CAS 56598-97-1C18H16N2O4
5,5-Diethoxy-1,3-diphenyl-2,4-imidazolidinedione chemical structure, C19H20N2O4, CAS 31274-54-1
5,5-Diethoxy-1,3-diphenyl-2,4-imidazolidinedione
CAS 31274-54-1C19H20N2O4
1,3-Diphenylimidazolidine-2,4-dione chemical structure, C15H12N2O2, CAS 3157-03-7
1,3-Diphenylimidazolidine-2,4-dione
CAS 3157-03-7C15H12N2O2
Benzenesulfonamide, 3-chloro-4-(2,5-dioxo-3-phenyl-1-imidazolidinyl)- chemical structure, C15H12ClN3O4S, CAS 53297-94-2
Benzenesulfonamide, 3-chloro-4-(2,5-dioxo-3-phenyl-1-imidazolidinyl)-
CAS 53297-94-2C15H12ClN3O4S
Benzenesulfonamide, 4-(2,4-dioxo-3-phenyl-1-imidazolidinyl)- chemical structure, C15H13N3O4S, CAS 53298-16-1
Benzenesulfonamide, 4-(2,4-dioxo-3-phenyl-1-imidazolidinyl)-
CAS 53298-16-1C15H13N3O4S
Benzenesulfonamide, 4-(2,5-dioxo-3-phenyl-1-imidazolidinyl)- chemical structure, C15H13N3O4S, CAS 53298-17-2
Benzenesulfonamide, 4-(2,5-dioxo-3-phenyl-1-imidazolidinyl)-
CAS 53298-17-2C15H13N3O4S
Benzenesulfonamide, 3-chloro-4-(3-(2-methylphenyl)-2,5-dioxo-1-imidazolidinyl)- chemical structure, C16H14ClN3O4S, CAS 65513-52-2
Benzenesulfonamide, 3-chloro-4-(3-(2-methylphenyl)-2,5-dioxo-1-imidazolidinyl)-
CAS 65513-52-2C16H14ClN3O4S
Benzenesulfonamide, 4-(3-(2-methylphenyl)-2,5-dioxo-1-imidazolidinyl)- chemical structure, C16H15N3O4S, CAS 65513-53-3
Benzenesulfonamide, 4-(3-(2-methylphenyl)-2,5-dioxo-1-imidazolidinyl)-
CAS 65513-53-3C16H15N3O4S
Benzoic acid, 3-[3-(3-methoxyphenyl)-2,4-dioxo-1-imidazolidinyl]- chemical structure, C17H14N2O5, CAS 651748-52-6
Benzoic acid, 3-[3-(3-methoxyphenyl)-2,4-dioxo-1-imidazolidinyl]-
CAS 651748-52-6C17H14N2O5
Benzoic acid, 3-[3-[4-(1-methylethyl)phenyl]-2,5-dioxo-1-imidazolidinyl]- chemical structure, C19H18N2O4, CAS 651748-42-4
Benzoic acid, 3-[3-[4-(1-methylethyl)phenyl]-2,5-dioxo-1-imidazolidinyl]-
CAS 651748-42-4C19H18N2O4
Benzoic acid, 3-[3-(4-iodophenyl)-2,5-dioxo-1-imidazolidinyl]- chemical structure, C16H11IN2O4, CAS 651748-64-0
Benzoic acid, 3-[3-(4-iodophenyl)-2,5-dioxo-1-imidazolidinyl]-
CAS 651748-64-0C16H11IN2O4
Benzoic acid, 3-[3-(4-methylphenyl)-2,5-dioxo-1-imidazolidinyl]- chemical structure, C17H14N2O4, CAS 651748-67-3
Benzoic acid, 3-[3-(4-methylphenyl)-2,5-dioxo-1-imidazolidinyl]-
CAS 651748-67-3C17H14N2O4
Benzoic acid, 3-[3-(4-ethoxyphenyl)-2,5-dioxo-1-imidazolidinyl]- chemical structure, C18H16N2O5, CAS 651748-68-4
Benzoic acid, 3-[3-(4-ethoxyphenyl)-2,5-dioxo-1-imidazolidinyl]-
CAS 651748-68-4C18H16N2O5
Benzoic acid, 3-[3-(3-bromophenyl)-2,5-dioxo-1-imidazolidinyl]- chemical structure, C16H11BrN2O4, CAS 651748-59-3
Benzoic acid, 3-[3-(3-bromophenyl)-2,5-dioxo-1-imidazolidinyl]-
CAS 651748-59-3C16H11BrN2O4
Benzoic acid, 3-[3-(2-fluorophenyl)-2,4-dioxo-1-imidazolidinyl]- chemical structure, C16H11FN2O4, CAS 651748-51-5
Benzoic acid, 3-[3-(2-fluorophenyl)-2,4-dioxo-1-imidazolidinyl]-
CAS 651748-51-5C16H11FN2O4
Benzoic acid, 3-[3-[4-(1-methylethyl)phenyl]-2,4-dioxo-1-imidazolidinyl]- chemical structure, C19H18N2O4, CAS 651748-50-4
Benzoic acid, 3-[3-[4-(1-methylethyl)phenyl]-2,4-dioxo-1-imidazolidinyl]-
CAS 651748-50-4C19H18N2O4
Benzoic acid, 3-[3-(2,3-dichlorophenyl)-2,4-dioxo-1-imidazolidinyl]- chemical structure, C16H10Cl2N2O4, CAS 651748-65-1
Benzoic acid, 3-[3-(2,3-dichlorophenyl)-2,4-dioxo-1-imidazolidinyl]-
CAS 651748-65-1C16H10Cl2N2O4
Benzoic acid, 3-[3-(4-bromophenyl)-2,5-dioxo-1-imidazolidinyl]- chemical structure, C16H11BrN2O4, CAS 651748-70-8
Benzoic acid, 3-[3-(4-bromophenyl)-2,5-dioxo-1-imidazolidinyl]-
CAS 651748-70-8C16H11BrN2O4
2,4-Imidazolidinedione, 5,5-dimethoxy-1,3-diphenyl- chemical structure, C17H16N2O4, CAS 43109-63-3
2,4-Imidazolidinedione, 5,5-dimethoxy-1,3-diphenyl-
CAS 43109-63-3C17H16N2O4