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Murcko scaffold

1,3,4-Oxadiazole, 2-5-diphenyl- scaffold

322 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
322
With full pages
64
Scaffold SMILES

c1ccc(-c2nnc(-c3ccccc3)o2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1,3,4-Oxadiazole, 2-5-diphenyl- page
Murcko scaffold c1ccc(-c2nnc(-c3ccccc3)o2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 322 chemicals

1,3,4-Oxadiazole, 2-5-diphenyl- chemical structure, C14H10N2O, CAS 725-12-2
1,3,4-Oxadiazole, 2-5-diphenyl-
CAS 725-12-2C14H10N2O
2,5-Bis-(4-nitro-phenyl)-(1,3,4)oxadiazole chemical structure, C14H8N4O5, CAS 1044-49-1
2,5-Bis-(4-nitro-phenyl)-(1,3,4)oxadiazole
CAS 1044-49-1C14H8N4O5
2,5-Bis(4-methylphenyl)-1,3,4-oxadiazole chemical structure, C16H14N2O, CAS 2491-91-0
2,5-Bis(4-methylphenyl)-1,3,4-oxadiazole
CAS 2491-91-0C16H14N2O
1,3,4-Oxadiazole, 2,5-bis(4-methoxy-3-nitrophenyl)- chemical structure, C16H12N4O7, CAS 5306-39-8
1,3,4-Oxadiazole, 2,5-bis(4-methoxy-3-nitrophenyl)-
CAS 5306-39-8C16H12N4O7
2,5-Bis(2-aminophenyl)-1,3,4-oxadiazole chemical structure, C14H12N4O, CAS 19542-04-2
2,5-Bis(2-aminophenyl)-1,3,4-oxadiazole
CAS 19542-04-2C14H12N4O
1,3,4-Oxadiazole, 2,5-bis(2-methylphenyl)- chemical structure, C16H14N2O, CAS 22020-68-4
1,3,4-Oxadiazole, 2,5-bis(2-methylphenyl)-
CAS 22020-68-4C16H14N2O
1,3,4-Oxadiazole, 2,5-bis(3,4,5-trimethoxyphenyl)- chemical structure, C20H22N2O7, CAS 23288-95-1
1,3,4-Oxadiazole, 2,5-bis(3,4,5-trimethoxyphenyl)-
CAS 23288-95-1C20H22N2O7
1,3,4-Oxadiazole, 2,5-bis(4-chloro-3-nitrophenyl)- chemical structure, C14H6Cl2N4O5, CAS 25423-74-9
1,3,4-Oxadiazole, 2,5-bis(4-chloro-3-nitrophenyl)-
CAS 25423-74-9C14H6Cl2N4O5
1,3,4-Oxadiazole, 2,5-bis(3-methylphenyl)- chemical structure, C16H14N2O, CAS 59646-37-6
1,3,4-Oxadiazole, 2,5-bis(3-methylphenyl)-
CAS 59646-37-6C16H14N2O
2-(4-Methoxyphenyl)-5-phenyl-1,3,4-oxadiazole chemical structure, C15H12N2O2, CAS 842-79-5
2-(4-Methoxyphenyl)-5-phenyl-1,3,4-oxadiazole
CAS 842-79-5C15H12N2O2
2,5-Bis(4-methoxyphenyl)-1,3,4-oxadiazole chemical structure, C16H14N2O3, CAS 847-39-2
2,5-Bis(4-methoxyphenyl)-1,3,4-oxadiazole
CAS 847-39-2C16H14N2O3
2-(4-Fluorophenyl)-5-phenyl-1,3,4-oxadiazole chemical structure, C14H9FN2O, CAS 1580-50-3
2-(4-Fluorophenyl)-5-phenyl-1,3,4-oxadiazole
CAS 1580-50-3C14H9FN2O
Benzenamine, 4,4'-(1,3,4-oxadiazole-2,5-diyl)bis[N,N-diethyl- chemical structure, C22H28N4O, CAS 1679-98-7
Benzenamine, 4,4'-(1,3,4-oxadiazole-2,5-diyl)bis[N,N-diethyl-
CAS 1679-98-7C22H28N4O
2-(3-Methoxyphenyl)-5-phenyl-1,3,4-oxadiazole chemical structure, C15H12N2O2, CAS 1874-41-5
2-(3-Methoxyphenyl)-5-phenyl-1,3,4-oxadiazole
CAS 1874-41-5C15H12N2O2
2-(2-Methoxyphenyl)-5-phenyl-1,3,4-oxadiazole chemical structure, C15H12N2O2, CAS 1874-42-6
2-(2-Methoxyphenyl)-5-phenyl-1,3,4-oxadiazole
CAS 1874-42-6C15H12N2O2
4,4'-(1,3,4-Oxadiazole-2,5-diyl)dianiline chemical structure, C14H12N4O, CAS 2425-95-8
4,4'-(1,3,4-Oxadiazole-2,5-diyl)dianiline
CAS 2425-95-8C14H12N4O
2,5-Bis(4-chlorophenyl)-1,3,4-oxadiazole chemical structure, C14H8Cl2N2O, CAS 2491-90-9
2,5-Bis(4-chlorophenyl)-1,3,4-oxadiazole
CAS 2491-90-9C14H8Cl2N2O
2,5-Bis(3-methoxyphenyl)-1,3,4-oxadiazole chemical structure, C16H14N2O3, CAS 19748-58-4
2,5-Bis(3-methoxyphenyl)-1,3,4-oxadiazole
CAS 19748-58-4C16H14N2O3
2-(4-Bromophenyl)-5-phenyl-1,3,4-oxadiazole chemical structure, C14H9BrN2O, CAS 21510-43-0
2-(4-Bromophenyl)-5-phenyl-1,3,4-oxadiazole
CAS 21510-43-0C14H9BrN2O
2-(3-Bromophenyl)-5-phenyl-1,3,4-oxadiazole chemical structure, C14H9BrN2O, CAS 83817-44-1
2-(3-Bromophenyl)-5-phenyl-1,3,4-oxadiazole
CAS 83817-44-1C14H9BrN2O
2-(2-Bromophenyl)-5-phenyl-1,3,4-oxadiazole chemical structure, C14H9BrN2O, CAS 83817-43-0
2-(2-Bromophenyl)-5-phenyl-1,3,4-oxadiazole
CAS 83817-43-0C14H9BrN2O
2-(2-Fluorophenyl)-5-phenyl-1,3,4-oxadiazole chemical structure, C14H9FN2O, CAS 62681-96-3
2-(2-Fluorophenyl)-5-phenyl-1,3,4-oxadiazole
CAS 62681-96-3C14H9FN2O
2-(3-Fluorophenyl)-5-phenyl-1,3,4-oxadiazole chemical structure, C14H9FN2O, CAS 62681-97-4
2-(3-Fluorophenyl)-5-phenyl-1,3,4-oxadiazole
CAS 62681-97-4C14H9FN2O
2-(2,4-Dichlorophenyl)-5-phenyl-1,3,4-oxadiazole chemical structure, C14H8Cl2N2O, CAS 62682-01-3
2-(2,4-Dichlorophenyl)-5-phenyl-1,3,4-oxadiazole
CAS 62682-01-3C14H8Cl2N2O