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Murcko scaffold

N-Phenyl-2-piperidinosuccinimide scaffold

140 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
140
With full pages
24
Scaffold SMILES

O=C1CC(N2CCCCC2)C(=O)N1c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-Phenyl-2-piperidinosuccinimide page
Murcko scaffold O=C1CC(N2CCCCC2)C(=O)N1c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 140 chemicals

N-Phenyl-2-piperidinosuccinimide chemical structure, C15H18N2O2, CAS 25110-41-2
N-Phenyl-2-piperidinosuccinimide
CAS 25110-41-2C15H18N2O2
1-(4-Methylphenyl)-3-(piperidin-1-yl)pyrrolidine-2,5-dione chemical structure, C16H20N2O2, CAS 89143-26-0
1-(4-Methylphenyl)-3-(piperidin-1-yl)pyrrolidine-2,5-dione
CAS 89143-26-0C16H20N2O2
1-(4-Iodophenyl)-3-(4-methylpiperidin-1-yl)pyrrolidine-2,5-dione chemical structure, C16H19IN2O2, CAS 312281-52-0
1-(4-Iodophenyl)-3-(4-methylpiperidin-1-yl)pyrrolidine-2,5-dione
CAS 312281-52-0C16H19IN2O2
1-(4-Methoxyphenyl)-3-(4-methyl-1-piperidinyl)-2,5-pyrrolidinedione chemical structure, C17H22N2O3, CAS 299408-30-3
1-(4-Methoxyphenyl)-3-(4-methyl-1-piperidinyl)-2,5-pyrrolidinedione
CAS 299408-30-3C17H22N2O3
1-(3-Chlorophenyl)-3-(4-methylpiperidino)pyrrolidine-2,5-dione chemical structure, C16H19ClN2O2, CAS 301354-71-2
1-(3-Chlorophenyl)-3-(4-methylpiperidino)pyrrolidine-2,5-dione
CAS 301354-71-2C16H19ClN2O2
1-[1-(4-Iodophenyl)-2,5-dioxopyrrolidin-3-yl]piperidine-4-carboxamide chemical structure, C16H18IN3O3, CAS 311792-96-8
1-[1-(4-Iodophenyl)-2,5-dioxopyrrolidin-3-yl]piperidine-4-carboxamide
CAS 311792-96-8C16H18IN3O3
Ethyl 1-[1-(3-methylphenyl)-2,5-dioxo-3-pyrrolidinyl]-3-piperidinecarboxylate chemical structure, C19H24N2O4, CAS 587005-51-4
Ethyl 1-[1-(3-methylphenyl)-2,5-dioxo-3-pyrrolidinyl]-3-piperidinecarboxylate
CAS 587005-51-4C19H24N2O4
4-Piperidinecarboxamide, 1-[1-(3-fluorophenyl)-2,5-dioxo-3-pyrrolidinyl]- chemical structure, C16H18FN3O3, CAS 590377-82-5
4-Piperidinecarboxamide, 1-[1-(3-fluorophenyl)-2,5-dioxo-3-pyrrolidinyl]-
CAS 590377-82-5C16H18FN3O3
2,5-Pyrrolidinedione, 1-(4-methoxyphenyl)-3-(1-piperidinyl)- chemical structure, C16H20N2O3, CAS 89143-27-1
2,5-Pyrrolidinedione, 1-(4-methoxyphenyl)-3-(1-piperidinyl)-
CAS 89143-27-1C16H20N2O3
2,5-Pyrrolidinedione, 1-(2-methoxyphenyl)-3-(1-piperidinyl)- chemical structure, C16H20N2O3, CAS 89143-25-9
2,5-Pyrrolidinedione, 1-(2-methoxyphenyl)-3-(1-piperidinyl)-
CAS 89143-25-9C16H20N2O3
1-(3-Methylphenyl)-3-piperidin-1-ylpyrrolidine-2,5-dione chemical structure, C16H20N2O2, CAS 301654-64-8
1-(3-Methylphenyl)-3-piperidin-1-ylpyrrolidine-2,5-dione
CAS 301654-64-8C16H20N2O2
1-(4-Bromophenyl)-3-(piperidin-1-yl)pyrrolidine-2,5-dione chemical structure, C15H17BrN2O2, CAS 195452-35-8
1-(4-Bromophenyl)-3-(piperidin-1-yl)pyrrolidine-2,5-dione
CAS 195452-35-8C15H17BrN2O2
1-(3-Chlorophenyl)-3-(piperidin-1-yl)pyrrolidine-2,5-dione chemical structure, C15H17ClN2O2, CAS 293765-99-8
1-(3-Chlorophenyl)-3-(piperidin-1-yl)pyrrolidine-2,5-dione
CAS 293765-99-8C15H17ClN2O2
1-(4-Chlorophenyl)-3-(piperidin-1-yl)pyrrolidine-2,5-dione chemical structure, C15H17ClN2O2, CAS 293766-01-5
1-(4-Chlorophenyl)-3-(piperidin-1-yl)pyrrolidine-2,5-dione
CAS 293766-01-5C15H17ClN2O2
1-(4-Bromophenyl)-3-(4-methyl-1-piperidinyl)-2,5-pyrrolidinedione chemical structure, C16H19BrN2O2, CAS 294873-43-1
1-(4-Bromophenyl)-3-(4-methyl-1-piperidinyl)-2,5-pyrrolidinedione
CAS 294873-43-1C16H19BrN2O2
1-(4-Chlorophenyl)-3-(4-methyl-1-piperidinyl)-2,5-pyrrolidinedione chemical structure, C16H19ClN2O2, CAS 299408-39-2
1-(4-Chlorophenyl)-3-(4-methyl-1-piperidinyl)-2,5-pyrrolidinedione
CAS 299408-39-2C16H19ClN2O2
3-(2-Ethylpiperidin-1-yl)-1-(4-methoxyphenyl)pyrrolidine-2,5-dione chemical structure, C18H24N2O3, CAS 299408-33-6
3-(2-Ethylpiperidin-1-yl)-1-(4-methoxyphenyl)pyrrolidine-2,5-dione
CAS 299408-33-6C18H24N2O3
1-(4-Bromophenyl)-3-(2-ethylpiperidin-1-yl)pyrrolidine-2,5-dione chemical structure, C17H21BrN2O2, CAS 301354-76-7
1-(4-Bromophenyl)-3-(2-ethylpiperidin-1-yl)pyrrolidine-2,5-dione
CAS 301354-76-7C17H21BrN2O2
1-(3-Bromophenyl)-3-(4-methylpiperidin-1-yl)pyrrolidine-2,5-dione chemical structure, C16H19BrN2O2, CAS 331245-21-7
1-(3-Bromophenyl)-3-(4-methylpiperidin-1-yl)pyrrolidine-2,5-dione
CAS 331245-21-7C16H19BrN2O2
4-(2,5-Dioxo-3-piperidin-1-yl-pyrrolidin-1-yl)-benzoic acid chemical structure, C16H18N2O4, CAS 311314-35-9
4-(2,5-Dioxo-3-piperidin-1-yl-pyrrolidin-1-yl)-benzoic acid
CAS 311314-35-9C16H18N2O4
3-(4-Methylpiperidin-1-yl)-1-phenylpyrrolidine-2,5-dione chemical structure, C16H20N2O2, CAS 311314-13-3
3-(4-Methylpiperidin-1-yl)-1-phenylpyrrolidine-2,5-dione
CAS 311314-13-3C16H20N2O2
1-(4-Ethoxyphenyl)-3-(4-methylpiperidin-1-yl)pyrrolidine-2,5-dione chemical structure, C18H24N2O3, CAS 332125-91-4
1-(4-Ethoxyphenyl)-3-(4-methylpiperidin-1-yl)pyrrolidine-2,5-dione
CAS 332125-91-4C18H24N2O3
1-[1-(4-Chlorophenyl)-2,5-dioxopyrrolidin-3-yl]piperidine-4-carboxylic acid chemical structure, C16H17ClN2O4, CAS 311334-21-1
1-[1-(4-Chlorophenyl)-2,5-dioxopyrrolidin-3-yl]piperidine-4-carboxylic acid
CAS 311334-21-1C16H17ClN2O4
1-[1-(4-Methoxyphenyl)-2,5-dioxopyrrolidin-3-yl]piperidine-4-carboxylic acid chemical structure, C17H20N2O5, CAS 314038-37-4
1-[1-(4-Methoxyphenyl)-2,5-dioxopyrrolidin-3-yl]piperidine-4-carboxylic acid
CAS 314038-37-4C17H20N2O5