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Murcko scaffold

Ring system with 3 rings and 15 atoms

20 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
15
Chemicals
20
With full pages
4
Scaffold SMILES

c1cc(C2CCC2)ccc1B1OCCO1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1cc(C2CCC2)ccc1B1OCCO1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 20 of 20 chemicals

1-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]cyclobutanamine chemical structure, C16H24BNO2, CAS 1362243-39-7
1-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]cyclobutanamine
CAS 1362243-39-7C16H24BNO2
1,1-Dimethylethyl N-[3-hydroxy-3-(hydroxymethyl)-1-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]cyclobutyl]carbamate chemical structure, C22H34BNO6, CAS 1245831-51-9
1,1-Dimethylethyl N-[3-hydroxy-3-(hydroxymethyl)-1-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]cyclobutyl]carbamate
CAS 1245831-51-9C22H34BNO6
tert-Butyl methyl(1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclobutyl)carbamate chemical structure, C22H34BNO4, CAS 1245831-59-7
tert-Butyl methyl(1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclobutyl)carbamate
CAS 1245831-59-7C22H34BNO4
1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclobutanecarbonitrile chemical structure, C17H22BNO2, CAS 1245831-55-3
1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclobutanecarbonitrile
CAS 1245831-55-3C17H22BNO2
tert-Butyl (trans-3-hydroxy-3-methyl-1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclobutyl)carbamate chemical structure, C22H34BNO5, CAS 1245770-25-5
tert-Butyl (trans-3-hydroxy-3-methyl-1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclobutyl)carbamate
CAS 1245770-25-5C22H34BNO5
tert-Butyl (1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclobutyl)carbamate chemical structure, C21H32BNO4, CAS 1032528-06-5
tert-Butyl (1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclobutyl)carbamate
CAS 1032528-06-5C21H32BNO4
Ethyl 1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclobutane-1-carboxylate chemical structure, C19H27BO4, CAS 1257213-69-6
Ethyl 1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclobutane-1-carboxylate
CAS 1257213-69-6C19H27BO4
trans-3-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]cyclobutan-1-ol chemical structure, C16H23BO3, CAS 1312478-69-5
trans-3-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]cyclobutan-1-ol
CAS 1312478-69-5C16H23BO3
(1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclobutyl)methanamine chemical structure, C17H26BNO2, CAS 1338547-12-8
(1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclobutyl)methanamine
CAS 1338547-12-8C17H26BNO2
(1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclobutyl)methanol chemical structure, C17H25BO3, CAS 1398331-84-4
(1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclobutyl)methanol
CAS 1398331-84-4C17H25BO3
(4-Cyclobutylphenyl)boronic acid pinacol ester chemical structure, C16H23BO2, CAS 2121513-90-2
(4-Cyclobutylphenyl)boronic acid pinacol ester
CAS 2121513-90-2C16H23BO2
1-(3,5-Difluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclobutanol chemical structure, C16H21BF2O3, CAS 1395282-06-0
1-(3,5-Difluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclobutanol
CAS 1395282-06-0C16H21BF2O3
Methyl 1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclobutane-1-carboxylate chemical structure, C18H25BO4, CAS 1423704-86-2
Methyl 1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclobutane-1-carboxylate
CAS 1423704-86-2C18H25BO4
1-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]cyclobutanol chemical structure, C16H23BO3, CAS 1398331-98-0
1-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]cyclobutanol
CAS 1398331-98-0C16H23BO3
tert-Butyl (1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclobutyl)methylcarbamate chemical structure, C22H34BNO4, CAS 1338543-73-9
tert-Butyl (1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclobutyl)methylcarbamate
CAS 1338543-73-9C22H34BNO4
2-[4-(1-Methoxycyclobutyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane chemical structure, C17H25BO3, CAS 1857375-29-1
2-[4-(1-Methoxycyclobutyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
CAS 1857375-29-1C17H25BO3
2-(4-(3,3-Difluorocyclobutyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane chemical structure, C16H21BF2O2, CAS 2361225-63-8
2-(4-(3,3-Difluorocyclobutyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
CAS 2361225-63-8C16H21BF2O2
2-(4-Cyclobutyl-2-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane chemical structure, C17H25BO3, CAS 2677885-94-6
2-(4-Cyclobutyl-2-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
CAS 2677885-94-6C17H25BO3
1-(3-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclobutane-1-carbonitrile chemical structure, C17H21BFNO2, CAS 2326492-11-7
1-(3-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclobutane-1-carbonitrile
CAS 2326492-11-7C17H21BFNO2
1-[2-Chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]cyclobutanol chemical structure, C16H22BClO3, CAS 2870698-00-1
1-[2-Chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]cyclobutanol
CAS 2870698-00-1C16H22BClO3