CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 20 atoms

7 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
7
With full pages
6
Scaffold SMILES

O=C(CSc1nncs1)NCc1ccc2c(c1)OCO2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CSc1nncs1)NCc1ccc2c(c1)OCO2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 7 of 7 chemicals

N-(1,3-Benzodioxol-5-ylmethyl)-2-[(5-methyl-1,3,4-thiadiazol-2-yl)thio]acetamide chemical structure, C13H13N3O3S2, CAS 670273-03-7
N-(1,3-Benzodioxol-5-ylmethyl)-2-[(5-methyl-1,3,4-thiadiazol-2-yl)thio]acetamide
CAS 670273-03-7C13H13N3O3S2
N-(5-((2-((Benzo[d][1,3]dioxol-5-ylmethyl)amino)-2-oxoethyl)thio)-1,3,4-thiadiazol-2-yl)isobutyramide chemical structure, C16H18N4O4S2, CAS 868972-76-3
N-(5-((2-((Benzo[d][1,3]dioxol-5-ylmethyl)amino)-2-oxoethyl)thio)-1,3,4-thiadiazol-2-yl)isobutyramide
CAS 868972-76-3C16H18N4O4S2
N-(5-((2-((Benzo[d][1,3]dioxol-5-ylmethyl)amino)-2-oxoethyl)thio)-1,3,4-thiadiazol-2-yl)-3-methylbutanamide chemical structure, C17H20N4O4S2, CAS 893148-81-7
N-(5-((2-((Benzo[d][1,3]dioxol-5-ylmethyl)amino)-2-oxoethyl)thio)-1,3,4-thiadiazol-2-yl)-3-methylbutanamide
CAS 893148-81-7C17H20N4O4S2
N-[5-[2-(1,3-Benzodioxol-5-ylmethylamino)-2-oxoethyl]sulfanyl-1,3,4-thiadiazol-2-yl]propanamide chemical structure, C15H16N4O4S2, CAS 868974-41-8
N-[5-[2-(1,3-Benzodioxol-5-ylmethylamino)-2-oxoethyl]sulfanyl-1,3,4-thiadiazol-2-yl]propanamide
CAS 868974-41-8C15H16N4O4S2
N-[5-[2-(1,3-Benzodioxol-5-ylmethylamino)-2-oxoethyl]sulfanyl-1,3,4-thiadiazol-2-yl]butanamide chemical structure, C16H18N4O4S2, CAS 868976-23-2
N-[5-[2-(1,3-Benzodioxol-5-ylmethylamino)-2-oxoethyl]sulfanyl-1,3,4-thiadiazol-2-yl]butanamide
CAS 868976-23-2C16H18N4O4S2
2-[(5-Acetamido-1,3,4-thiadiazol-2-yl)sulfanyl]-N-(1,3-benzodioxol-5-ylmethyl)acetamide chemical structure, C14H14N4O4S2, CAS 893156-61-1
2-[(5-Acetamido-1,3,4-thiadiazol-2-yl)sulfanyl]-N-(1,3-benzodioxol-5-ylmethyl)acetamide
CAS 893156-61-1C14H14N4O4S2
N-(Benzo[d][1,3]dioxol-5-ylmethyl)-2-((5-(2-(N-methylmethylsulfonamido)acetamido)-1,3,4-thiadiazol-2-yl)thio)acetamide chemical structure, C16H19N5O6S3, CAS 1351613-82-5
N-(Benzo[d][1,3]dioxol-5-ylmethyl)-2-((5-(2-(N-methylmethylsulfonamido)acetamido)-1,3,4-thiadiazol-2-yl)thio)acetamide
CAS 1351613-82-5C16H19N5O6S3