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Murcko scaffold

5H,6H-Pyrido(4,3-d)pyrimidin-5-one scaffold

18 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
18
With full pages
3
Scaffold SMILES

O=c1[nH]ccc2ncncc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 5H,6H-Pyrido(4,3-d)pyrimidin-5-one page
Murcko scaffold O=c1[nH]ccc2ncncc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 18 of 18 chemicals

5H,6H-Pyrido(4,3-d)pyrimidin-5-one chemical structure, C7H5N3O, CAS 74632-30-7
5H,6H-Pyrido(4,3-d)pyrimidin-5-one
CAS 74632-30-7C7H5N3O
Ethyl 7-amino-2-methyl-5-oxo-5,6-dihydropyrido[4,3-d]pyrimidine-8-carboxylate chemical structure, C11H12N4O3, CAS 924861-65-4
Ethyl 7-amino-2-methyl-5-oxo-5,6-dihydropyrido[4,3-d]pyrimidine-8-carboxylate
CAS 924861-65-4C11H12N4O3
Ethyl 2-(2-methylsulfanyl-5-oxopyrido[4,3-d]pyrimidin-6-yl)acetate chemical structure, C12H13N3O3S, CAS 902575-97-7
Ethyl 2-(2-methylsulfanyl-5-oxopyrido[4,3-d]pyrimidin-6-yl)acetate
CAS 902575-97-7C12H13N3O3S
2-(Methylsulfanyl)-5H,6H-pyrido(4,3-d)pyrimidin-5-one chemical structure, C8H7N3OS, CAS 902576-09-4
2-(Methylsulfanyl)-5H,6H-pyrido(4,3-d)pyrimidin-5-one
CAS 902576-09-4C8H7N3OS
2-Methylpyrido[4,3-d]pyrimidin-5(6H)-one chemical structure, C8H7N3O, CAS 1432381-18-4
2-Methylpyrido[4,3-d]pyrimidin-5(6H)-one
CAS 1432381-18-4C8H7N3O
2,4-Dimethylpyrido[4,3-d]pyrimidin-5(6H)-one chemical structure, C9H9N3O, CAS 651054-88-5
2,4-Dimethylpyrido[4,3-d]pyrimidin-5(6H)-one
CAS 651054-88-5C9H9N3O
8-Bromo-5H,6H-pyrido[4,3-d]pyrimidin-5-one chemical structure, C7H4BrN3O, CAS 1379345-98-8
8-Bromo-5H,6H-pyrido[4,3-d]pyrimidin-5-one
CAS 1379345-98-8C7H4BrN3O
8-Chloropyrido[4,3-d]pyrimidin-5(6H)-one chemical structure, C7H4ClN3O, CAS 1378972-04-3
8-Chloropyrido[4,3-d]pyrimidin-5(6H)-one
CAS 1378972-04-3C7H4ClN3O
8-Iodo-2-(methylthio)pyrido[4,3-d]pyrimidin-5(6H)-one chemical structure, C8H6IN3OS, CAS 1562987-77-2
8-Iodo-2-(methylthio)pyrido[4,3-d]pyrimidin-5(6H)-one
CAS 1562987-77-2C8H6IN3OS
8-Bromo-6-methylpyrido[4,3-d]pyrimidin-5(6H)-one chemical structure, C8H6BrN3O, CAS 1706751-60-1
8-Bromo-6-methylpyrido[4,3-d]pyrimidin-5(6H)-one
CAS 1706751-60-1C8H6BrN3O
2-Aminopyrido[4,3-d]pyrimidin-5(6H)-one chemical structure, C7H6N4O, CAS 2737897-92-4
2-Aminopyrido[4,3-d]pyrimidin-5(6H)-one
CAS 2737897-92-4C7H6N4O
2-Chloropyrido[4,3-D]pyrimidin-5(6H)-one chemical structure, C7H4ClN3O, CAS 1393570-12-1
2-Chloropyrido[4,3-D]pyrimidin-5(6H)-one
CAS 1393570-12-1C7H4ClN3O
2-Methanesulfonyl-5H,6H-pyrido[4,3-d]pyrimidin-5-one chemical structure, C8H7N3O3S, CAS 2309462-37-9
2-Methanesulfonyl-5H,6H-pyrido[4,3-d]pyrimidin-5-one
CAS 2309462-37-9C8H7N3O3S
8-Methylpyrido[4,3-d]pyrimidin-5-ol chemical structure, C8H7N3O, CAS 2137816-43-2
8-Methylpyrido[4,3-d]pyrimidin-5-ol
CAS 2137816-43-2C8H7N3O
8-Propylpyrido[4,3-d]pyrimidin-5-ol chemical structure, C10H11N3O, CAS 2137754-36-8
8-Propylpyrido[4,3-d]pyrimidin-5-ol
CAS 2137754-36-8C10H11N3O
8-Ethylpyrido[4,3-d]pyrimidin-5-ol chemical structure, C9H9N3O, CAS 2138426-75-0
8-Ethylpyrido[4,3-d]pyrimidin-5-ol
CAS 2138426-75-0C9H9N3O
8-Bromo-2-(methylthio)pyrido[4,3-d]pyrimidin-5(6H)-one chemical structure, C8H6BrN3OS, CAS 2762684-10-4
8-Bromo-2-(methylthio)pyrido[4,3-d]pyrimidin-5(6H)-one
CAS 2762684-10-4C8H6BrN3OS
8-Chloro-2-methylsulfanyl-6H-pyrido[4,3-d]pyrimidin-5-one chemical structure, C8H6ClN3OS, CAS 2762684-11-5
8-Chloro-2-methylsulfanyl-6H-pyrido[4,3-d]pyrimidin-5-one
CAS 2762684-11-5C8H6ClN3OS