Murcko scaffold
Benzisothiazole scaffold
560 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 9
- Chemicals
- 560
- With full pages
- 41
Scaffold SMILES
c1ccc2sncc2c1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 145 to 192 of 560 chemicals
5-Nitro-1,2-benzothiazole-3-carbaldehyde
CAS 70061-56-2C8H4N2O3S
5-Nitro-1,2-benzothiazole-3-carboxylic acid
CAS 70061-57-3C8H4N2O4S
![3-Methylbenzo[d]isothiazol-5-ol chemical structure, C8H7NOS, CAS 73437-07-7](/s/QZKPMWHDGBMXNE-UHFFFAOYSA-N.svg)
3-Methylbenzo[d]isothiazol-5-ol
CAS 73437-07-7C8H7NOS
![5-Methoxy-3-methylbenzo[d]isothiazole chemical structure, C9H9NOS, CAS 73437-09-9](/s/ULFRJNWTELNRHG-UHFFFAOYSA-N.svg)
5-Methoxy-3-methylbenzo[d]isothiazole
CAS 73437-09-9C9H9NOS
5-Bromo-3-(bromomethyl)-1,2-benzothiazole
CAS 73437-12-4C8H5Br2NS
![Benzo[d]isothiazol-3-ylmethanamine chemical structure, C8H8N2S, CAS 1931085-47-0](/s/OLCBZIWAXGUORO-UHFFFAOYSA-N.svg)
Benzo[d]isothiazol-3-ylmethanamine
CAS 1931085-47-0C8H8N2S
(5-Chloro-1,2-benzothiazol-3-yl)methanamine
CAS 343787-77-9C8H7ClN2S
(5-Bromo-1,2-benzothiazol-3-yl)methanamine
CAS 343787-74-6C8H7BrN2S
1,2-Benzothiazole-3-carbaldehyde
CAS 73437-27-1C8H5NOS
![7-Bromo-3-methylbenzo[d]isothiazole chemical structure, C8H6BrNS, CAS 75608-03-6](/s/WUOOMVPBFGYIRO-UHFFFAOYSA-N.svg)
7-Bromo-3-methylbenzo[d]isothiazole
CAS 75608-03-6C8H6BrNS
![4-Bromo-3-methylbenzo[d]isothiazole chemical structure, C8H6BrNS, CAS 75607-89-5](/s/QHCWWPHQHUFKBJ-UHFFFAOYSA-N.svg)
4-Bromo-3-methylbenzo[d]isothiazole
CAS 75607-89-5C8H6BrNS
![7-Chloro-3-methylbenzo[d]isothiazole chemical structure, C8H6ClNS, CAS 75608-05-8](/s/ZNZJEMBXFYJCKL-UHFFFAOYSA-N.svg)
7-Chloro-3-methylbenzo[d]isothiazole
CAS 75608-05-8C8H6ClNS
1,2-Benzothiazol-5-ol
CAS 75608-07-0C7H5NOS
N,N-Dimethyl-1,2-benzisothiazol-6-amine
CAS 60768-67-4C9H10N2S
![N,N-Dimethylbenzo[d]isothiazol-3-amine chemical structure, C9H10N2S, CAS 22801-55-4](/s/AXEPVTNANVZKQI-UHFFFAOYSA-N.svg)
N,N-Dimethylbenzo[d]isothiazol-3-amine
CAS 22801-55-4C9H10N2S
N,N-Diethyl-1,2-benzothiazol-3-amine
CAS 22961-84-8C11H14N2S
![Ethyl 2-[(7-nitro-1,2-benzisothiazol-4-yl)amino]-2-oxoacetate chemical structure, C11H9N3O5S, CAS 84387-65-5](/s/KJVSWLWCLSWHFO-UHFFFAOYSA-N.svg)
Ethyl 2-[(7-nitro-1,2-benzisothiazol-4-yl)amino]-2-oxoacetate
CAS 84387-65-5C11H9N3O5S
acetate chemical structure, C13H14N2O4S, CAS 84409-56-3](/s/UCERSJOCVQNGPX-UHFFFAOYSA-N.svg)
Ethyl [(4-ethoxy-1,2-benzothiazol-7-yl)amino](oxo)acetate
CAS 84409-56-3C13H14N2O4S
![7-Methoxybenzo[d]isothiazole chemical structure, C8H7NOS, CAS 88791-26-8](/s/VTYHEUZKGDJQNR-UHFFFAOYSA-N.svg)
7-Methoxybenzo[d]isothiazole
CAS 88791-26-8C8H7NOS
![7-Methoxybenzo[d]isothiazol-3-amine chemical structure, C8H8N2OS, CAS 88791-27-9](/s/NDCXQKAJSJQIMK-UHFFFAOYSA-N.svg)
7-Methoxybenzo[d]isothiazol-3-amine
CAS 88791-27-9C8H8N2OS
![7-Chlorobenzo[d]isothiazol-3-amine chemical structure, C7H5ClN2S, CAS 90407-19-5](/s/ZLTURSZPDLBZRD-UHFFFAOYSA-N.svg)
7-Chlorobenzo[d]isothiazol-3-amine
CAS 90407-19-5C7H5ClN2S
N,N-Dimethyl-5-nitro-1,2-benzothiazol-6-amine
CAS 88465-34-3C9H9N3O2S
(3-Methoxy-1,2-benzothiazol-5-yl)acetonitrile
CAS 65412-57-9C10H8N2OS
5-(Bromomethyl)-3-methoxy-1,2-benzothiazole
CAS 65412-53-5C9H8BrNOS
- 2-(1,2-Benzisothiazol-3-yloxy)acetamide94087-28-2C9H8N2O2S
- 1,2-Benzothiazole-3-carbonitrile16807-20-8C8H4N2S
- 3-Methoxy-1,2-benzisothiazole-5-acetic acid65412-52-4C10H9NO3S
- 3-Chloro-6-methoxy-1,2-benzisothiazole103486-07-3C8H6ClNOS
- 3-Chloro-5-methyl-1,2-benzothiazole19331-20-5C8H6ClNS
- N-1,2-Benzothiazol-3-yl-N~2~,N~2~-dimethylglycinamide109382-08-3C11H13N3OS
- N-1,2-Benzothiazol-3-yl-N~2~,N~2~-diethylglycinamide109382-09-4C13H17N3OS
- 3,7-Dimethyl-1,2-benzisothiazole110718-88-2C9H9NS
- 7-Methoxy-3-methylbenzo[d]isothiazole110718-89-3C9H9NOS
- 3,5-Dimethylbenzo[d]isothiazole40576-92-9C9H9NS
- 4-Methoxybenzo[d]isothiazol-3-amine127952-01-6C8H8N2OS
- 3,6-Dimethylbenzo[d]isothiazole134365-25-6C9H9NS
- 3-Methylbenzo[d]isothiazole-5-carboxylic acid135085-95-9C9H7NO2S
- 3-Chloro-4-methoxy-1,2-benzisothiazole103486-06-2C8H6ClNOS
- 3-Chloro-7-methoxy-1,2-benzisothiazole136546-52-6C8H6ClNOS
- 3-Chloro-5-methoxybenzo[d]isothiazole23889-41-0C8H6ClNOS
- 1,2-Benzothiazole-3-carboxamide16807-21-9C8H6N2OS
- Benzo[d]isothiazole-3-carbonyl chloride145759-64-4C8H4ClNOS
- 3-(1,2-Benzisothiazol-3-yloxy)propylamine94087-33-9C10H12N2OS
- ((1,2-Benzisothiazol-3-yloxy)methyl)(diethyl)amine94087-87-3C12H16N2OS
- 5-Bromobenzo[d]isothiazole-3-carboxylic acid677304-78-8C8H4BrNO2S
- 1 suppliers5-Bromo-1,2-benzothiazole139037-01-7C7H4BrNS
- 5-Fluorobenzo[d]isothiazole139037-02-8C7H4FNS
- 6-Bromo-1,2-benzothiazole877265-23-1C7H4BrNS
Related scaffolds
Same ring framework with different atoms or bond orders
![Scaffold c1ccc2[nH]ccc2c1](/scaffold/SIKJAQJRHWYJAI-UHFFFAOYSA-N/structure.svg)
c1ccc2[nH]ccc2c12,455 chemicals![Scaffold c1ccc2[nH]cnc2c1](/scaffold/HYZJCKYKOHLVJF-UHFFFAOYSA-N/structure.svg)
c1ccc2[nH]cnc2c11,206 chemicals![Scaffold c1ccc2[nH]ncc2c1](/scaffold/BAXOFTOLAUCFNW-UHFFFAOYSA-N/structure.svg)
c1ccc2[nH]ncc2c1795 chemicals
c1ccc2scnc2c1756 chemicals
c1ccc2occc2c1632 chemicals
c1ccc2c(c1)CCC2621 chemicals
c1ccc2c(c1)OCO2536 chemicals
c1ccc2sccc2c1529 chemicals
c1ccn2ccnc2c1525 chemicals
c1ccc2c(c1)CCN2440 chemicals![Scaffold O=c1[nH]c(=O)c2[nH]cnc2[nH]1](/scaffold/LRFVTYWOQMYALW-UHFFFAOYSA-N/structure.svg)
O=c1[nH]c(=O)c2[nH]cnc2[nH]1411 chemicals
O=C1NC(=O)c2ccccc21352 chemicals