Murcko scaffold
N-(Cyclohexylmethyl)benzenesulfonamide scaffold
52 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 17
- Chemicals
- 52
- With full pages
- 6
Scaffold SMILES
O=S(=O)(NCC1CCCCC1)c1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 52 chemicals
![(1R,4R)-4-[(4-Fluorobenzenesulfonamido)methyl]cyclohexane-1-carboxylic acid chemical structure, C14H18FNO4S, CAS 744248-54-2](/s/AISZJTPLQRGKDX-UHFFFAOYSA-N.svg)
(1R,4R)-4-[(4-Fluorobenzenesulfonamido)methyl]cyclohexane-1-carboxylic acid
CAS 744248-54-2C14H18FNO4S
![trans-4-({[(4-Methoxyphenyl)sulfonyl]amino}methyl)cyclohexanecarboxylic acid chemical structure, C15H21NO5S, CAS 1212395-78-2](/s/YFLHPSZYOOQOHT-UHFFFAOYSA-N.svg)
trans-4-({[(4-Methoxyphenyl)sulfonyl]amino}methyl)cyclohexanecarboxylic acid
CAS 1212395-78-2C15H21NO5S
4-(((Phenylsulfonyl)amino)methyl)cyclohexanecarboxylic acid
CAS 443913-38-0C14H19NO4S
![(1r,4r)-4-[(4-Chlorobenzenesulfonamido)methyl]cyclohexane-1-carboxylic acid chemical structure, C14H18ClNO4S, CAS 674819-28-4](/s/QSAMXYYSGGMNTJ-UHFFFAOYSA-N.svg)
(1r,4r)-4-[(4-Chlorobenzenesulfonamido)methyl]cyclohexane-1-carboxylic acid
CAS 674819-28-4C14H18ClNO4S
3-Bromo-N-(cyclohexylmethyl)benzenesulfonamide
CAS 852228-52-5C13H18BrNO2S
![4-[({[4-(Acetylamino)phenyl]sulfonyl}amino)methyl]cyclohexanecarboxylic acid chemical structure, C16H22N2O5S, CAS 301827-49-6](/s/NCCWJIKLDMTYLD-UHFFFAOYSA-N.svg)
4-[({[4-(Acetylamino)phenyl]sulfonyl}amino)methyl]cyclohexanecarboxylic acid
CAS 301827-49-6C16H22N2O5S
N-(Cyclohexylmethyl)-4-methylbenzenesulfonamide
CAS 86328-85-0C14H21NO2S
![2-[1-[[(4-Methylphenyl)sulfonylamino]methyl]cyclohexyl]acetic acid chemical structure, C16H23NO4S, CAS 7232-06-6](/s/CNTJKVYUZPNHKF-UHFFFAOYSA-N.svg)
2-[1-[[(4-Methylphenyl)sulfonylamino]methyl]cyclohexyl]acetic acid
CAS 7232-06-6C16H23NO4S
N-(Cyclohexylmethyl)benzenesulfonamide
CAS 26914-53-4C13H19NO2S
![[1-({[(4-Chlorophenyl)sulfonyl]amino}methyl)cyclohexyl]acetic acid chemical structure, C15H20ClNO4S, CAS 929850-34-0](/s/PVRBTYSULFFZLN-UHFFFAOYSA-N.svg)
[1-({[(4-Chlorophenyl)sulfonyl]amino}methyl)cyclohexyl]acetic acid
CAS 929850-34-0C15H20ClNO4S
![[1-({[(4-Methoxyphenyl)sulfonyl]amino}methyl)cyclohexyl]acetic acid chemical structure, C16H23NO5S, CAS 929830-68-2](/s/LKPGVKUBDYVBHL-UHFFFAOYSA-N.svg)
[1-({[(4-Methoxyphenyl)sulfonyl]amino}methyl)cyclohexyl]acetic acid
CAS 929830-68-2C16H23NO5S
![trans-N-{2-[(2-Methylpropyl)amino]-2-oxoethyl}-4-{[(phenylsulfonyl)amino]methyl}cyclohexanecarboxamide chemical structure, C20H31N3O4S, CAS 1212378-61-4](/s/JXCQMZCNJXSUFR-UHFFFAOYSA-N.svg)
trans-N-{2-[(2-Methylpropyl)amino]-2-oxoethyl}-4-{[(phenylsulfonyl)amino]methyl}cyclohexanecarboxamide
CAS 1212378-61-4C20H31N3O4S
![trans-N-{(2S)-1-[(2-methoxyethyl)amino]-1-oxopropan-2-yl}-4-{[(phenylsulfonyl)amino]methyl}cyclohexanecarboxamide chemical structure, C20H31N3O5S, CAS 1212092-67-5](/s/HGRLBDKUJRMARY-GTPINHCMSA-N.svg)
trans-N-{(2S)-1-[(2-methoxyethyl)amino]-1-oxopropan-2-yl}-4-{[(phenylsulfonyl)amino]methyl}cyclohexanecarboxamide
CAS 1212092-67-5C20H31N3O5S
![trans-4-({[(4-Methoxyphenyl)sulfonyl]amino}methyl)-N-{(2S)-1-[(2-methylpropyl)amino]-1-oxopropan-2-yl}cyclohexanecarboxamide chemical structure, C22H35N3O5S, CAS 1212404-21-1](/s/GGBZXZCOEMDQBG-AOCRQIFASA-N.svg)
trans-4-({[(4-Methoxyphenyl)sulfonyl]amino}methyl)-N-{(2S)-1-[(2-methylpropyl)amino]-1-oxopropan-2-yl}cyclohexanecarboxamide
CAS 1212404-21-1C22H35N3O5S
![trans-4-({[(4-Fluorophenyl)sulfonyl]amino}methyl)-N-{2-[(2-methoxyethyl)amino]-2-oxoethyl}cyclohexanecarboxamide chemical structure, C19H28FN3O5S, CAS 1212387-17-1](/s/YCOWINSGPGMXBO-UHFFFAOYSA-N.svg)
trans-4-({[(4-Fluorophenyl)sulfonyl]amino}methyl)-N-{2-[(2-methoxyethyl)amino]-2-oxoethyl}cyclohexanecarboxamide
CAS 1212387-17-1C19H28FN3O5S
![trans-4-({[(4-Fluorophenyl)sulfonyl]amino}methyl)-N-{2-[(2-hydroxyethyl)amino]-2-oxoethyl}cyclohexanecarboxamide chemical structure, C18H26FN3O5S, CAS 1212281-57-6](/s/QIIKLLNDKKSZAL-UHFFFAOYSA-N.svg)
trans-4-({[(4-Fluorophenyl)sulfonyl]amino}methyl)-N-{2-[(2-hydroxyethyl)amino]-2-oxoethyl}cyclohexanecarboxamide
CAS 1212281-57-6C18H26FN3O5S
4-(Cyclohexylmethyl-sulfamoyl)-benzoic acid
CAS 891017-60-0C14H19NO4S
4-Bromo-N-(cyclohexylmethyl)benzenesulfonamide
CAS 321703-07-5C13H18BrNO2S
![[1-(([(4-Fluorophenyl)sulfonyl]amino)methyl)cyclohexyl]acetic acid chemical structure, C15H20FNO4S, CAS 1176582-75-4](/s/CFJAKYRESNAMSD-UHFFFAOYSA-N.svg)
[1-(([(4-Fluorophenyl)sulfonyl]amino)methyl)cyclohexyl]acetic acid
CAS 1176582-75-4C15H20FNO4S
![(1-[(([4-(Acetylamino)phenyl]sulfonyl)amino)methyl]cyclohexyl)acetic acid chemical structure, C17H24N2O5S, CAS 1175804-00-8](/s/QDROQXXETZZESM-UHFFFAOYSA-N.svg)
(1-[(([4-(Acetylamino)phenyl]sulfonyl)amino)methyl]cyclohexyl)acetic acid
CAS 1175804-00-8C17H24N2O5S
3-(N-(Cyclohexylmethyl)sulfamoyl)benzoic acid
CAS 1054509-26-0C14H19NO4S
![Benzoic acid, 3-[[(cyclohexylmethyl)amino]sulfonyl]-4-methyl- chemical structure, C15H21NO4S, CAS 1050884-78-0](/s/NQEIGOPJGUXCLS-UHFFFAOYSA-N.svg)
Benzoic acid, 3-[[(cyclohexylmethyl)amino]sulfonyl]-4-methyl-
CAS 1050884-78-0C15H21NO4S
![N-[(1-Aminocyclohexyl)methyl]-2-nitrobenzene-1-sulfonamide chemical structure, C13H19N3O4S, CAS 1153056-70-2](/s/HVWGKZIBBOHWSX-UHFFFAOYSA-N.svg)
N-[(1-Aminocyclohexyl)methyl]-2-nitrobenzene-1-sulfonamide
CAS 1153056-70-2C13H19N3O4S
![N-[(1-Aminocyclohexyl)methyl]-4-nitrobenzene-1-sulfonamide chemical structure, C13H19N3O4S, CAS 1153056-72-4](/s/RMIANUDJEGVZSM-UHFFFAOYSA-N.svg)
N-[(1-Aminocyclohexyl)methyl]-4-nitrobenzene-1-sulfonamide
CAS 1153056-72-4C13H19N3O4S
- N-[(1-Aminocyclohexyl)methyl]-4-methylbenzene-1-sulfonamide1153056-83-7C14H22N2O2S
- 3-[(Cyclohexylmethylamino)sulfonyl]-4-methoxybenzoic acid1052478-67-7C15H21NO5S
- (1r,4S)-N-((S)-1-((2-(Dimethylamino)ethyl)amino)-1-oxopropan-2-yl)-4-((4-fluorophenylsulfonamido)methyl)cyclohexanecarboxamide1212237-28-9C21H33FN4O4S
- (4-(N-(Cyclohexylmethyl)sulfamoyl)phenyl)boronic acid1221823-27-3C13H20BNO4S
- 2-Nitro-N-{[(1r,4r)-4-(aminomethyl)cyclohexyl]methyl}benzene-1-sulfonamide486453-63-8C14H21N3O4S
- Benzenesulfonamide, N-[[2-(chloromethyl)cyclohexyl]methyl]-3-methyl-1482057-88-4C15H22ClNO2S
- 5-[(Cyclohexylmethyl)sulfamoyl]-2-methoxybenzoic acid89704-52-9C15H21NO5S
- 2-Chloro-5-[(cyclohexylmethyl)sulfamoyl]benzene-1-sulfonyl chloride92071-55-1C13H17Cl2NO4S2
- N-{[1-(Hydroxymethyl)cyclohexyl]methyl}-4-methylbenzene-1-sulfonamide1216981-05-3C15H23NO3S
- N-[(1-Aminocyclohexyl)methyl]-4-methylbenzene-1-sulfonamide hydrochloride1423032-54-5C14H23ClN2O2S
- N-[(1-Aminocyclohexyl)methyl]-4-nitrobenzene-1-sulfonamide hydrochloride1595068-76-0C13H20ClN3O4S
- N-(2-Amino-1-cyclohexylethyl)-4-nitrobenzene-1-sulfonamide hydrochloride1795490-20-8C14H22ClN3O4S
- N-(2-Amino-1-cyclohexylethyl)-4-nitrobenzene-1-sulfonamide1795773-24-8C14H21N3O4S
- N-[(2-Aminocyclohexyl)methyl]-4-nitrobenzene-1-sulfonamide hydrochloride1798716-40-1C13H20ClN3O4S
- N-[(2-Aminocyclohexyl)methyl]-4-nitrobenzene-1-sulfonamide1798883-23-4C13H19N3O4S
- (4-Methoxy-3-(N-((4-methoxycyclohexyl)methyl)sulfamoyl)phenyl)boronic acid1704082-65-4C15H24BNO6S
- 3-Amino-4-chloro-5-methyl-N-[(1-methylcyclohexyl)methyl]benzene-1-sulfonamide1939770-00-9C15H23ClN2O2S
- N-(2-Amino-1-cyclohexylethyl)-2-nitrobenzene-1-sulfonamide1568635-90-4C14H21N3O4S
- (1r,4S)-N-((S)-1-((2-Hydroxyethyl)amino)-1-oxopropan-2-yl)-4-((4-methoxyphenylsulfonamido)methyl)cyclohexanecarboxamide1212290-07-7C20H31N3O6S
- (1r,4r)-4-((3-(Trifluoromethyl)phenylsulfonamido)methyl)cyclohexanecarboxylic acid2909244-31-9C15H18F3NO4S
- 3,4-Dichloro-N-{[1-(dimethylamino)cyclohexyl]methyl}benzene-1-sulfonamide753389-49-0C15H22Cl2N2O2S
- 3,4-Dichloro-N-{[1-(dimethylamino)cyclohexyl]methyl}benzenesulfonamide hydrochloride (1:1)41805-08-7C15H23Cl3N2O2S
- N-[(4-Aminocyclohexyl)methyl]-2-nitrobenzene-1-sulfonamide2138125-14-9C13H19N3O4S
- 4-Nitro-N-{[(1r,4r)-4-(aminomethyl)cyclohexyl]methyl}benzene-1-sulfonamide2137078-75-0C14H21N3O4S
Related scaffolds
Same ring framework with different atoms or bond orders
O=C(Nc1ccccc1)Nc1ccccc1421 chemicals
O=C(C=Cc1ccccc1)c1ccccc1389 chemicals
O=C(NCc1ccccc1)c1ccccc1260 chemicals
O=C(Cc1ccccc1)Nc1ccccc1219 chemicals
O=S(=O)(NCc1ccccc1)c1ccccc1164 chemicals
c1ccc(CNCc2ccccc2)cc1142 chemicals
S=C(Nc1ccccc1)Nc1ccccc1109 chemicals
O=C(CCc1ccccc1)c1ccccc187 chemicals
C(=NNc1ccccc1)c1ccccc173 chemicals
O=C(Nc1ccccc1)Oc1ccccc173 chemicals
O=C(OCc1ccccc1)N1CCCCC161 chemicals
O=C(OCc1ccccc1)c1ccccc157 chemicals