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Murcko scaffold

Ring system with 4 rings and 22 atoms

5 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
22
Chemicals
5
With full pages
1
Scaffold SMILES

O=c1c(Cc2ccccc2)c[nH]n1-c1nc2ccccc2[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1c(Cc2ccccc2)c[nH]n1-c1nc2ccccc2[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 5 of 5 chemicals

1-(1H-Benzo[d]imidazol-2-yl)-4-benzyl-3-methyl-1H-pyrazol-5-ol chemical structure, C18H16N4O, CAS 1006582-11-1
1-(1H-Benzo[d]imidazol-2-yl)-4-benzyl-3-methyl-1H-pyrazol-5-ol
CAS 1006582-11-1C18H16N4O
1-(1H-Benzimidazol-2-yl)-4-(4-bromobenzyl)-3-methyl-1H-pyrazol-5-ol chemical structure, C18H15BrN4O, CAS 944780-05-6
1-(1H-Benzimidazol-2-yl)-4-(4-bromobenzyl)-3-methyl-1H-pyrazol-5-ol
CAS 944780-05-6C18H15BrN4O
1-(1H-Benzimidazol-2-yl)-4-(4-tert-butylbenzyl)-3-methyl-1H-pyrazol-5-ol chemical structure, C22H24N4O, CAS 944782-89-2
1-(1H-Benzimidazol-2-yl)-4-(4-tert-butylbenzyl)-3-methyl-1H-pyrazol-5-ol
CAS 944782-89-2C22H24N4O
1-(1H-Benzimidazol-2-yl)-3-methyl-4-[4-(propan-2-yl)benzyl]-1H-pyrazol-5-ol chemical structure, C21H22N4O, CAS 944788-41-4
1-(1H-Benzimidazol-2-yl)-3-methyl-4-[4-(propan-2-yl)benzyl]-1H-pyrazol-5-ol
CAS 944788-41-4C21H22N4O
Huhs015 chemical structure, C19H18N4O, CAS 1453097-13-6
Huhs015
CAS 1453097-13-6C19H18N4O