Murcko scaffold
2-Azabicyclo(2.2.2)octan-3-one scaffold
27 chemicals on CompoundList share this ring system.
- Rings
- 3
- Scaffold atoms
- 9
- Chemicals
- 27
- With full pages
- 3
Scaffold SMILES
O=C1NC2CCC1CC2
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 27 of 27 chemicals
2-Azabicyclo(2.2.2)octan-3-one
CAS 3306-69-2C7H11NO
6-Hydroxy-2-methyl-2-azabicyclo(2.2.2)octan-3-one
CAS 38025-74-0C8H13NO2
![2-Azabicyclo[2.2.2]octan-3-one, 2-nitroso- chemical structure, C7H10N2O2, CAS 82897-02-7](/s/VQRHGYDLWPLPIU-UHFFFAOYSA-N.svg)
2-Azabicyclo[2.2.2]octan-3-one, 2-nitroso-
CAS 82897-02-7C7H10N2O2
![2,2-Dimethyl-N-(3-oxo-2-azabicyclo[2.2.2]oct-4-yl)dodecanamide chemical structure, C21H38N2O2, CAS 876620-70-1](/s/WXJYAFKCMBQGGL-UHFFFAOYSA-N.svg)
2,2-Dimethyl-N-(3-oxo-2-azabicyclo[2.2.2]oct-4-yl)dodecanamide
CAS 876620-70-1C21H38N2O2
![2-Fluoro-2-azabicyclo[2.2.2]octan-3-one chemical structure, C7H10FNO, CAS 88842-37-9](/s/YCKWZHNJOCHNKU-UHFFFAOYSA-N.svg)
2-Fluoro-2-azabicyclo[2.2.2]octan-3-one
CAS 88842-37-9C7H10FNO
![Ethyl 3-oxo-2-azabicyclo[2.2.2]octane-4-carboxylate chemical structure, C10H15NO3, CAS 21933-15-3](/s/ICSDOPIVXVXHFP-UHFFFAOYSA-N.svg)
Ethyl 3-oxo-2-azabicyclo[2.2.2]octane-4-carboxylate
CAS 21933-15-3C10H15NO3
![5-Hydroxy-2-azabicyclo[2.2.2]octan-3-one chemical structure, C7H11NO2, CAS 750634-07-2](/s/JIYWBCGWFWAIGY-UHFFFAOYSA-N.svg)
5-Hydroxy-2-azabicyclo[2.2.2]octan-3-one
CAS 750634-07-2C7H11NO2
![4-Amino-2-azabicyclo[2.2.2]octan-3-one chemical structure, C7H12N2O, CAS 1314932-75-6](/s/RROOBYWPBOEAAW-UHFFFAOYSA-N.svg)
4-Amino-2-azabicyclo[2.2.2]octan-3-one
CAS 1314932-75-6C7H12N2O
![Methyl 3-oxo-2-azabicyclo[2.2.2]octane-1-carboxylate chemical structure, C9H13NO3, CAS 21239-95-2](/s/KVFFDMZQDNBPLW-UHFFFAOYSA-N.svg)
Methyl 3-oxo-2-azabicyclo[2.2.2]octane-1-carboxylate
CAS 21239-95-2C9H13NO3
![3-Oxo-2-azabicyclo[2.2.2]octane-4-carboxylic acid chemical structure, C8H11NO3, CAS 1379192-35-4](/s/OCQKKLPLFXCQJN-UHFFFAOYSA-N.svg)
3-Oxo-2-azabicyclo[2.2.2]octane-4-carboxylic acid
CAS 1379192-35-4C8H11NO3
![Methyl 3-oxo-2-azabicyclo[2.2.2]octane-4-carboxylate chemical structure, C9H13NO3, CAS 2031259-75-1](/s/HSUGBJMOIFXRJU-UHFFFAOYSA-N.svg)
Methyl 3-oxo-2-azabicyclo[2.2.2]octane-4-carboxylate
CAS 2031259-75-1C9H13NO3
![3-Oxo-2-azabicyclo[2.2.2]octane-1-carboxamide chemical structure, C8H12N2O2, CAS 21121-49-3](/s/ZJFZROAUBAUZLZ-UHFFFAOYSA-N.svg)
3-Oxo-2-azabicyclo[2.2.2]octane-1-carboxamide
CAS 21121-49-3C8H12N2O2
![6-Hydroxy-2-azabicyclo[2.2.2]octan-3-one chemical structure, C7H11NO2, CAS 1824545-19-8](/s/OUSZAYOCRVHPSR-UHFFFAOYSA-N.svg)
6-Hydroxy-2-azabicyclo[2.2.2]octan-3-one
CAS 1824545-19-8C7H11NO2
![1-Methyl-2-azabicyclo[2.2.2]octan-3-one chemical structure, C8H13NO, CAS 59498-99-6](/s/ZGTWVZLQGHNXHT-UHFFFAOYSA-N.svg)
1-Methyl-2-azabicyclo[2.2.2]octan-3-one
CAS 59498-99-6C8H13NO
![1-(Hydroxymethyl)-2-azabicyclo[2.2.2]octan-3-one chemical structure, C8H13NO2, CAS 1334412-35-9](/s/TWYQQDHZKSEDPD-UHFFFAOYSA-N.svg)
1-(Hydroxymethyl)-2-azabicyclo[2.2.2]octan-3-one
CAS 1334412-35-9C8H13NO2
![3-Oxo-2-azabicyclo[2.2.2]octane-1-carboxylic acid chemical structure, C8H11NO3, CAS 21129-83-9](/s/LDRHBUBQXDHMGT-UHFFFAOYSA-N.svg)
3-Oxo-2-azabicyclo[2.2.2]octane-1-carboxylic acid
CAS 21129-83-9C8H11NO3
![5-Amino-2-azabicyclo[2.2.2]octan-3-one chemical structure, C7H12N2O, CAS 1894928-71-2](/s/ICKGRRATTQLENV-UHFFFAOYSA-N.svg)
5-Amino-2-azabicyclo[2.2.2]octan-3-one
CAS 1894928-71-2C7H12N2O
![tert-Butyl 3-oxo-2-azabicyclo[2.2.2]octane-2-carboxylate chemical structure, C12H19NO3, CAS 2007916-87-0](/s/MFDABLWVOJYWGI-UHFFFAOYSA-N.svg)
tert-Butyl 3-oxo-2-azabicyclo[2.2.2]octane-2-carboxylate
CAS 2007916-87-0C12H19NO3
![N-Methyl-3-oxo-2-azabicyclo[2.2.2]octane-1-carboxamide chemical structure, C9H14N2O2, CAS 21121-50-6](/s/CIRARCOFRQAFCF-UHFFFAOYSA-N.svg)
N-Methyl-3-oxo-2-azabicyclo[2.2.2]octane-1-carboxamide
CAS 21121-50-6C9H14N2O2
![4-(Aminomethyl)-2-azabicyclo[2.2.2]octan-3-one hydrochloride chemical structure, C8H15ClN2O, CAS 2378502-40-8](/s/VGLAAXVOZXWEJT-UHFFFAOYSA-N.svg)
4-(Aminomethyl)-2-azabicyclo[2.2.2]octan-3-one hydrochloride
CAS 2378502-40-8C8H15ClN2O
![4-(Aminomethyl)-2-azabicyclo[2.2.2]octan-3-one chemical structure, C8H14N2O, CAS 2378502-39-5](/s/JQMMRUHPHZQERR-UHFFFAOYSA-N.svg)
4-(Aminomethyl)-2-azabicyclo[2.2.2]octan-3-one
CAS 2378502-39-5C8H14N2O
![2-(tert-Butyl) 4-ethyl 3-oxo-2-azabicyclo[2.2.2]Octane-2,4-dicarboxylate chemical structure, C15H23NO5, CAS 2306263-26-1](/s/HZSOAXHPDPIWKY-UHFFFAOYSA-N.svg)
2-(tert-Butyl) 4-ethyl 3-oxo-2-azabicyclo[2.2.2]Octane-2,4-dicarboxylate
CAS 2306263-26-1C15H23NO5
![3-Oxo-2-azabicyclo[2.2.2]octane-1-carbaldehyde chemical structure, C8H11NO2, CAS 2816909-83-6](/s/NDHXFDJZHICLMK-UHFFFAOYSA-N.svg)
3-Oxo-2-azabicyclo[2.2.2]octane-1-carbaldehyde
CAS 2816909-83-6C8H11NO2
![2,5,5-Trimethyl-2-azabicyclo[2.2.2]octan-3-one chemical structure, C10H17NO, CAS 4029-28-1](/s/IAGSDLZNDOVUFK-UHFFFAOYSA-N.svg)
2,5,5-Trimethyl-2-azabicyclo[2.2.2]octan-3-one
CAS 4029-28-1C10H17NO
Related scaffolds
Same ring framework with different atoms or bond orders
