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Murcko scaffold

Bicyclo(2.2.2)octan-2-one scaffold

85 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
9
Chemicals
85
With full pages
13
Scaffold SMILES

O=C1CC2CCC1CC2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Bicyclo(2.2.2)octan-2-one page
Murcko scaffold O=C1CC2CCC1CC2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 85 chemicals

Bicyclo(2.2.2)octan-2-one chemical structure, C8H12O, CAS 2716-23-6
Bicyclo(2.2.2)octan-2-one
CAS 2716-23-6C8H12O
1,5,5-Trimethyl-8-oxobicyclo[2.2.2]octane-2,3-dicarboxylic acid chemical structure, C13H18O5, CAS 50317-24-3
1,5,5-Trimethyl-8-oxobicyclo[2.2.2]octane-2,3-dicarboxylic acid
CAS 50317-24-3C13H18O5
4-Hydroxy-1-methylbicyclo[2.2.2]octan-2-one chemical structure, C9H14O2, CAS 5122-77-0
4-Hydroxy-1-methylbicyclo[2.2.2]octan-2-one
CAS 5122-77-0C9H14O2
4-Chloro-1-methylbicyclo[2.2.2]octan-2-one chemical structure, C9H13ClO, CAS 7697-12-3
4-Chloro-1-methylbicyclo[2.2.2]octan-2-one
CAS 7697-12-3C9H13ClO
4-Fluoro-1-methylbicyclo[2.2.2]octan-2-one chemical structure, C9H13FO, CAS 502141-71-1
4-Fluoro-1-methylbicyclo[2.2.2]octan-2-one
CAS 502141-71-1C9H13FO
6-Oxobicyclo(2.2.2)octane-2-carboxylic acid chemical structure, C9H12O3, CAS 2308961-67-1
6-Oxobicyclo(2.2.2)octane-2-carboxylic acid
CAS 2308961-67-1C9H12O3
3,3-Dichlorobicyclo[2.2.2]octan-2-one chemical structure, C8H10Cl2O, CAS 23804-49-1
3,3-Dichlorobicyclo[2.2.2]octan-2-one
CAS 23804-49-1C8H10Cl2O
Bicyclo(2.2.2)octanone, 3-methyl- chemical structure, C9H14O, CAS 26051-25-2
Bicyclo(2.2.2)octanone, 3-methyl-
CAS 26051-25-2C9H14O
4-Methoxybicyclo[2.2.2]octan-2-one chemical structure, C9H14O2, CAS 4893-16-7
4-Methoxybicyclo[2.2.2]octan-2-one
CAS 4893-16-7C9H14O2
1-Bromo-4-methoxybicyclo[2.2.2]octan-2-one chemical structure, C9H13BrO2, CAS 88888-28-2
1-Bromo-4-methoxybicyclo[2.2.2]octan-2-one
CAS 88888-28-2C9H13BrO2
1-Heptyl-4-hydroxybicyclo[2.2.2]octan-2-one chemical structure, C15H26O2, CAS 76921-56-7
1-Heptyl-4-hydroxybicyclo[2.2.2]octan-2-one
CAS 76921-56-7C15H26O2
(1R,4S,6S)-6-Methoxybicyclo[2.2.2]octan-2-one chemical structure, C9H14O2, CAS 182210-85-1
(1R,4S,6S)-6-Methoxybicyclo[2.2.2]octan-2-one
CAS 182210-85-1C9H14O2
(1S,4R,6R)-6-Acetyl-1,3,3-trimethylbicyclo[2.2.2]octan-2-one chemical structure, C13H20O2, CAS 132152-67-1
(1S,4R,6R)-6-Acetyl-1,3,3-trimethylbicyclo[2.2.2]octan-2-one
CAS 132152-67-1C13H20O2
Methyl (1R,2S,4R)-rel-5-oxobicyclo[2.2.2]octane-2-carboxylate chemical structure, C10H14O3, CAS 146611-35-0
Methyl (1R,2S,4R)-rel-5-oxobicyclo[2.2.2]octane-2-carboxylate
CAS 146611-35-0C10H14O3
Bicyclo[2.2.2]octanone, 6-hydroxy-4-methyl-, (1R,4S,6R)-(9CI) chemical structure, C9H14O2, CAS 615280-27-8
Bicyclo[2.2.2]octanone, 6-hydroxy-4-methyl-, (1R,4S,6R)-(9CI)
CAS 615280-27-8C9H14O2
Methyl 5-oxobicyclo[2.2.2]octane-2-carboxylate chemical structure, C10H14O3, CAS 78478-61-2
Methyl 5-oxobicyclo[2.2.2]octane-2-carboxylate
CAS 78478-61-2C10H14O3
rac-Methyl (1R,2R,4R)-5-oxobicyclo[2.2.2]octane-2-carboxylate chemical structure, C10H14O3, CAS 49826-55-3
rac-Methyl (1R,2R,4R)-5-oxobicyclo[2.2.2]octane-2-carboxylate
CAS 49826-55-3C10H14O3
Methyl 3-oxobicyclo[2.2.2]octane-2-carboxylate chemical structure, C10H14O3, CAS 30144-30-0
Methyl 3-oxobicyclo[2.2.2]octane-2-carboxylate
CAS 30144-30-0C10H14O3
Ethyl 4-hydroxy-2-oxo-bicyclo[2.2.2]octane-1-carboxylate chemical structure, C11H16O4, CAS 72948-76-6
Ethyl 4-hydroxy-2-oxo-bicyclo[2.2.2]octane-1-carboxylate
CAS 72948-76-6C11H16O4
3,3-Dimethylbicyclo[2.2.2]octan-2-one chemical structure, C10H16O, CAS 50682-96-7
3,3-Dimethylbicyclo[2.2.2]octan-2-one
CAS 50682-96-7C10H16O
4-Methoxy-2-oxobicyclo[2.2.2]octane-1-carboxylic acid chemical structure, C10H14O4, CAS 81687-89-0
4-Methoxy-2-oxobicyclo[2.2.2]octane-1-carboxylic acid
CAS 81687-89-0C10H14O4
Ethyl 4-methoxy-2-oxobicyclo[2.2.2]octane-1-carboxylate chemical structure, C12H18O4, CAS 81687-88-9
Ethyl 4-methoxy-2-oxobicyclo[2.2.2]octane-1-carboxylate
CAS 81687-88-9C12H18O4
Methyl 2-cyano-5-oxobicyclo[2.2.2]octane-2-carboxylate chemical structure, C11H13NO3, CAS 2649017-27-4
Methyl 2-cyano-5-oxobicyclo[2.2.2]octane-2-carboxylate
CAS 2649017-27-4C11H13NO3
Methyl (1R,2R,4R)-2-cyano-5-oxobicyclo[2.2.2]octane-2-carboxylate chemical structure, C11H13NO3, CAS 84959-05-7
Methyl (1R,2R,4R)-2-cyano-5-oxobicyclo[2.2.2]octane-2-carboxylate
CAS 84959-05-7C11H13NO3