Murcko scaffold
2-Oxabicyclo[2.2.2]octane scaffold
275 chemicals on CompoundList share this ring system.
- Rings
- 3
- Scaffold atoms
- 8
- Chemicals
- 275
- With full pages
- 67
Scaffold SMILES
C1CC2CCC1CO2
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 275 chemicals
1,8-Cineole
CAS 470-82-6C10H18O
![(1s,4r,6s)-1,3,3-Trimethyl-2-oxabicyclo[2.2.2]octan-6-ol chemical structure, C10H18O2, CAS 60761-00-4](/s/YVCUGZBVCHODNB-WEDXCCLWSA-N.svg)
(1s,4r,6s)-1,3,3-Trimethyl-2-oxabicyclo[2.2.2]octan-6-ol
CAS 60761-00-4C10H18O2
Listerine
CAS 51273-66-6C30H52O3
Epomediol
CAS 56084-15-2C10H18O3
![2-Oxabicyclo[2.2.2]octan-6-ol, 1,3,3-trimethyl-, 6-acetate chemical structure, C12H20O3, CAS 72257-53-5](/s/XRKZFZWIYZDOQO-UHFFFAOYSA-N.svg)
2-Oxabicyclo[2.2.2]octan-6-ol, 1,3,3-trimethyl-, 6-acetate
CAS 72257-53-5C12H20O3
![1,3,3-Trimethyl-2-oxabicyclo[2.2.2]octane-4,6-diol chemical structure, C10H18O3, CAS 99765-58-9](/s/PEWQMISWINPIPZ-UHFFFAOYSA-N.svg)
1,3,3-Trimethyl-2-oxabicyclo[2.2.2]octane-4,6-diol
CAS 99765-58-9C10H18O3
![(1R,4R,6R)-1,3,3-Trimethyl-2-oxabicyclo[2.2.2]octan-6-ol chemical structure, C10H18O2, CAS 54164-88-4](/s/YVCUGZBVCHODNB-NQMVMOMDSA-N.svg)
(1R,4R,6R)-1,3,3-Trimethyl-2-oxabicyclo[2.2.2]octan-6-ol
CAS 54164-88-4C10H18O2
Sesquicineole
CAS 90131-02-5C15H26O
exo-2-Hydroxycineole
CAS 18679-48-6C10H18O2
Clesidren
CAS 1310101-21-3C10H18O3
2-Oxabicyclo(2.2.2)octane, 1,5-dimethyl-3-(2-propenyl)-
C12H20O
![(1R,3R,4S,5S)-3-Butyl-1,5-dimethyl-2-oxabicyclo[2.2.2]octane chemical structure, C13H24O](/s/SENDFKGNJBUEOA-WUHRBBMRSA-N.svg)
(1R,3R,4S,5S)-3-Butyl-1,5-dimethyl-2-oxabicyclo[2.2.2]octane
C13H24O
![(1,5,8-Trimethyl-2-oxabicyclo[2.2.2]octan-4-yl)methyl acetate chemical structure, C13H22O3, CAS 331956-12-8](/s/XUKHTJZFVQWUKR-UHFFFAOYSA-N.svg)
(1,5,8-Trimethyl-2-oxabicyclo[2.2.2]octan-4-yl)methyl acetate
CAS 331956-12-8C13H22O3
6-endo-Hydroxycineole
CAS 66965-45-5C10H18O2
2-endo-Hydroxy-1,8-cineole
C10H18O2
![(1S,4S,5R,7S)-1,3,3-Trimethyl-2-oxabicyclo[2.2.2]octane-5,7-diol chemical structure, C10H18O3, CAS 219546-83-5](/s/RLNNVCTYJJOQLN-ODHVRURNSA-N.svg)
(1S,4S,5R,7S)-1,3,3-Trimethyl-2-oxabicyclo[2.2.2]octane-5,7-diol
CAS 219546-83-5C10H18O3
(1R,4R,6R)-1,3,3-Trimethyl-2-oxabicyclo(2.2.2)octane-4,6-diol
CAS 176896-61-0C10H18O3
2-Acetoxy-1,8-cineole, (+)-endo-
CAS 438619-71-7C12H20O3
![2-Oxabicyclo[2.2.2]octane-3,3-dicarboxylic acid, diethyl ester chemical structure, C13H20O5, CAS 61779-31-5](/s/SFPNKHIKMRMXFH-UHFFFAOYSA-N.svg)
2-Oxabicyclo[2.2.2]octane-3,3-dicarboxylic acid, diethyl ester
CAS 61779-31-5C13H20O5
![2-Oxabicyclo[2.2.2]octane-3,3-dicarboxylic acid chemical structure, C9H12O5, CAS 61779-37-1](/s/KAARCFGDJJRYRV-UHFFFAOYSA-N.svg)
2-Oxabicyclo[2.2.2]octane-3,3-dicarboxylic acid
CAS 61779-37-1C9H12O5
![6-Iodo-1,3,3-trimethyl-2-oxabicyclo[2.2.2]octane chemical structure, C10H17IO, CAS 94922-00-6](/s/SZQVPXRKWXKUAT-UHFFFAOYSA-N.svg)
6-Iodo-1,3,3-trimethyl-2-oxabicyclo[2.2.2]octane
CAS 94922-00-6C10H17IO
![2-Oxabicyclo[2.2.2]octan-6-ol chemical structure, C7H12O2, CAS 107553-90-2](/s/FTZJTRSNTLVUSK-UHFFFAOYSA-N.svg)
2-Oxabicyclo[2.2.2]octan-6-ol
CAS 107553-90-2C7H12O2
![3-(4-Methoxy-4-methylpentyl)-1,3-dimethyl-2-oxabicyclo[2.2.2]octane chemical structure, C16H30O2, CAS 140848-21-1](/s/WWSALUKTRXVHPB-UHFFFAOYSA-N.svg)
3-(4-Methoxy-4-methylpentyl)-1,3-dimethyl-2-oxabicyclo[2.2.2]octane
CAS 140848-21-1C16H30O2
![(3,3-Dimethyl-2-oxabicyclo[2.2.2]octan-1-yl)methanol chemical structure, C10H18O2, CAS 135521-14-1](/s/VQVMQGQKIHRZQF-UHFFFAOYSA-N.svg)
(3,3-Dimethyl-2-oxabicyclo[2.2.2]octan-1-yl)methanol
CAS 135521-14-1C10H18O2
- 2-Oxabicyclo(2.2.2)octane-3-carboxylic acid61779-35-9C8H12O3
- 1 suppliers(1-Vinyl-2-oxabicyclo[2.2.2]octan-4-yl)methanol340023-03-2C10H16O2
- 1-Ethenyl-2-oxabicyclo[2.2.2]octane-4-carboxylic acid340023-04-3C10H14O3
- 2-Oxabicyclo(2.2.2)octane, 3-butyl-1,5-dimethyl-72230-90-1C13H24O
- 1,5-Dimethyl-3-(prop-2-en-1-yl)-2-oxabicyclo[2.2.2]octane71477-76-4C12H20O
- 4-Chloro-1,3,3-trimethyl-2-oxabicyclo[2.2.2]octane88444-51-3C10H17ClO
- 1-(Chloromethyl)-3,3-dimethyl-2-oxabicyclo[2.2.2]octane88444-52-4C10H17ClO
- 2-Oxabicyclo[2.2.2]octane280-39-7C7H12O
- 1,3,3-Trimethyl-2-oxabicyclo[2.2.2]octane-5,6-diol87791-02-4C10H18O3
- Acetamide, N,N-diethyl-2-(1,8-epoxy-p-menth-2-ylamino)-93189-95-8C16H30N2O2
- Acetamide, 2-(dipropylamino)-N-(1,8-epoxy-p-menth-2-yl)-94376-14-4C18H34N2O2
- Acetamide, N,N-dipropyl-2-((1,8-epoxy-p-menth-2-yl)amino)-94376-16-6C18H34N2O2
- 1,8-Cineol-d31216822-66-0C10H18O
- 6-Hydroxy-2-oxabicyclo[2.2.2]octane-4-carbonitrile1251017-81-8C8H11NO2
- 2-Oxabicyclo[2.2.2]octane-4-carbaldehyde1212021-23-2C8H12O2
- (1-Vinyl-2-oxabicyclo[2.2.2]octan-4-yl)methyl acetate340023-02-1C12H18O3
- tert-Butyl (1-(2-hydroxyethyl)-2-oxabicyclo[2.2.2]octan-4-yl)carbamate1417551-57-5C14H25NO4
- 3-(Chloromethyl)-1,3-dimethyl-2-oxabicyclo[2.2.2]octane88444-53-5C10H17ClO
- Benzoic acid--(1,3-dimethyl-2-oxabicyclo[2.2.2]octan-3-yl)methanol (1/1)88444-58-0C17H24O4
- 3-(Hydroxymethyl)-1,3-dimethyl-2-oxabicyclo[2.2.2]octan-4-ol93682-64-5C10H18O3
- 1,3-Dimethyl-2-oxabicyclo[2.2.2]octane93704-87-1C9H16O
- 4-Bromo-1,3,3-trimethyl-2-oxabicyclo[2.2.2]octane110219-74-4C10H17BrO
- 1,3-Dimethyl-2-oxabicyclo[2.2.2]octane-3-carboxylic acid72447-55-3C10H16O3
- 6-Bromo-3-(dibromomethyl)-1,4-dimethyl-2-oxabicyclo[2.2.2]octane919172-29-5C10H15Br3O
Related scaffolds
Same ring framework with different atoms or bond orders
