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Murcko scaffold

2,3-Dihydro-1,3-thiazol-2-one scaffold

153 chemicals on CompoundList share this ring system.

Rings
1
Scaffold atoms
6
Chemicals
153
With full pages
29
Scaffold SMILES

O=c1[nH]ccs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.

Substructure search with this scaffoldOpen the 2,3-Dihydro-1,3-thiazol-2-one page
Murcko scaffold O=c1[nH]ccs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 153 chemicals

5-Ethyl-4-methylthiazol-2(3H)-one chemical structure, C6H9NOS, CAS 51806-83-8
5-Ethyl-4-methylthiazol-2(3H)-one
CAS 51806-83-8C6H9NOS
4-Methyl-2,3-dihydro-1,3-thiazol-2-one chemical structure, C4H5NOS, CAS 32497-10-2
4-Methyl-2,3-dihydro-1,3-thiazol-2-one
CAS 32497-10-2C4H5NOS
2,4-Dihydroxythiazole-5-acetic acid chemical structure, C5H5NO4S, CAS 6628-19-9
2,4-Dihydroxythiazole-5-acetic acid
CAS 6628-19-9C5H5NO4S
5-Nitro-2,3-dihydro-1,3-thiazol-2-one chemical structure, C3H2N2O3S, CAS 3034-49-9
5-Nitro-2,3-dihydro-1,3-thiazol-2-one
CAS 3034-49-9C3H2N2O3S
2,4-Dihydroxythiazole chemical structure, C3H3NO2S, CAS 625-85-4
2,4-Dihydroxythiazole
CAS 625-85-4C3H3NO2S
(4-Chloro-5-formyl-2-oxo-thiazol-3-yl)-acetic acid ethyl ester chemical structure, C8H8ClNO4S, CAS 487037-12-7
(4-Chloro-5-formyl-2-oxo-thiazol-3-yl)-acetic acid ethyl ester
CAS 487037-12-7C8H8ClNO4S
4-Amino-2,5-thiazoledione 5-oxime chemical structure, C3H3N3O2S, CAS 19967-61-4
4-Amino-2,5-thiazoledione 5-oxime
CAS 19967-61-4C3H3N3O2S
2-(4-Methyl-2-oxo-2,3-dihydro-1,3-thiazol-3-yl)acetic acid chemical structure, C6H7NO3S, CAS 68104-03-0
2-(4-Methyl-2-oxo-2,3-dihydro-1,3-thiazol-3-yl)acetic acid
CAS 68104-03-0C6H7NO3S
Ethyl 2-oxo-4-(trifluoromethyl)-2,3-dihydro-1,3-thiazole-5-carboxylate chemical structure, C7H6F3NO3S, CAS 72850-53-4
Ethyl 2-oxo-4-(trifluoromethyl)-2,3-dihydro-1,3-thiazole-5-carboxylate
CAS 72850-53-4C7H6F3NO3S
4-Methyl-2-oxo-3(2H)-thiazolepropanoic acid chemical structure, C7H9NO3S, CAS 852399-57-6
4-Methyl-2-oxo-3(2H)-thiazolepropanoic acid
CAS 852399-57-6C7H9NO3S
3,4-Dimethyl-2(3H)-thiazolone chemical structure, C5H7NOS, CAS 32497-11-3
3,4-Dimethyl-2(3H)-thiazolone
CAS 32497-11-3C5H7NOS
4-Methyl-2-oxo-3(2H)-thiazolebutanoic acid chemical structure, C8H11NO3S, CAS 854137-79-4
4-Methyl-2-oxo-3(2H)-thiazolebutanoic acid
CAS 854137-79-4C8H11NO3S
3-(2-Bromoethyl)-4-methyl-2,3-dihydro-1,3-thiazol-2-one chemical structure, C6H8BrNOS, CAS 847744-20-1
3-(2-Bromoethyl)-4-methyl-2,3-dihydro-1,3-thiazol-2-one
CAS 847744-20-1C6H8BrNOS
2-(4-Methyl-2-oxo-2,3-dihydro-1,3-thiazol-3-yl)acetohydrazide chemical structure, C6H9N3O2S, CAS 879361-60-1
2-(4-Methyl-2-oxo-2,3-dihydro-1,3-thiazol-3-yl)acetohydrazide
CAS 879361-60-1C6H9N3O2S
Phosphonic acid, (2,3-dihydro-2-oxo-5-thiazolyl)- chemical structure, C3H4NO4PS, CAS 167275-86-7
Phosphonic acid, (2,3-dihydro-2-oxo-5-thiazolyl)-
CAS 167275-86-7C3H4NO4PS
2-Hydroxy-thiazole-5-carboxylic acid methyl ester chemical structure, C5H5NO3S, CAS 56417-51-7
2-Hydroxy-thiazole-5-carboxylic acid methyl ester
CAS 56417-51-7C5H5NO3S
Ethyl 2-hydroxy-4-methyl-1,3-thiazole-5-carboxylate chemical structure, C7H9NO3S, CAS 40235-78-7
Ethyl 2-hydroxy-4-methyl-1,3-thiazole-5-carboxylate
CAS 40235-78-7C7H9NO3S
2,3-Dihydro-1,3-thiazol-2-one chemical structure, C3H3NOS, CAS 82358-07-4
2,3-Dihydro-1,3-thiazol-2-one
CAS 82358-07-4C3H3NOS
4-Chloro-2-oxo-2,3-dihydro-1,3-thiazole-5-carbaldehyde chemical structure, C4H2ClNO2S, CAS 55359-96-1
4-Chloro-2-oxo-2,3-dihydro-1,3-thiazole-5-carbaldehyde
CAS 55359-96-1C4H2ClNO2S
4-Chloro-3-methyl-2-oxo-2,3-dihydro-1,3-thiazole-5-carbaldehyde chemical structure, C5H4ClNO2S, CAS 57805-14-8
4-Chloro-3-methyl-2-oxo-2,3-dihydro-1,3-thiazole-5-carbaldehyde
CAS 57805-14-8C5H4ClNO2S
2-Oxo-2,3-dihydro-1,3-thiazol-4-yl acetate chemical structure, C5H5NO3S, CAS 62581-01-5
2-Oxo-2,3-dihydro-1,3-thiazol-4-yl acetate
CAS 62581-01-5C5H5NO3S
4,5-Dichloro-1,3-thiazol-2(3H)-one chemical structure, C3HCl2NOS, CAS 62019-48-1
4,5-Dichloro-1,3-thiazol-2(3H)-one
CAS 62019-48-1C3HCl2NOS
4-tert-Butyl-2,3-dihydro-1,3-thiazol-2-one chemical structure, C7H11NOS, CAS 75820-45-0
4-tert-Butyl-2,3-dihydro-1,3-thiazol-2-one
CAS 75820-45-0C7H11NOS
5-Methyl-1,3-thiazol-2-ol chemical structure, C4H5NOS, CAS 79307-64-5
5-Methyl-1,3-thiazol-2-ol
CAS 79307-64-5C4H5NOS