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Murcko scaffold

Ring system with 4 rings and 25 atoms

5 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
25
Chemicals
5
With full pages
2
Scaffold SMILES

c1ccc(SCC2COC(Cn3ccnc3)(c3ccccc3)O2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(SCC2COC(Cn3ccnc3)(c3ccccc3)O2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 5 of 5 chemicals

Ethyl N-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methylsulfanyl]phenyl]carbamate chemical structure, C23H23Cl2N3O4S, CAS 95480-32-3
Ethyl N-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methylsulfanyl]phenyl]carbamate
CAS 95480-32-3C23H23Cl2N3O4S
Tubulozole hydrochloride chemical structure, C23H24Cl3N3O4S, CAS 83529-08-2
Tubulozole hydrochloride
CAS 83529-08-2C23H24Cl3N3O4S
Tubulozole chemical structure, C23H23Cl2N3O4S, CAS 84697-22-3
Tubulozole
CAS 84697-22-3C23H23Cl2N3O4S
cis-4-((2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl)methylthio)aniline dihydrochloride chemical structure, C20H21Cl4N3O2S, CAS 83929-39-9
cis-4-((2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl)methylthio)aniline dihydrochloride
CAS 83929-39-9C20H21Cl4N3O2S
Erbulozole chemical structure, C24H27N3O5S, CAS 124784-31-2
Erbulozole
CAS 124784-31-2C24H27N3O5S