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Murcko scaffold

Ring system with 4 rings and 19 atoms

16 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
19
Chemicals
16
With full pages
6
Scaffold SMILES

O=C1C(c2c[nH]c3ccccc23)=Nc2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1C(c2c[nH]c3ccccc23)=Nc2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 16 of 16 chemicals

Indirubin-5-sulfonate chemical structure, C16H10N2O5S, CAS 244021-67-8
Indirubin-5-sulfonate
CAS 244021-67-8C16H10N2O5S
2H-Indol-2-one, 3-(1,3-dihydro-3-oxo-2H-indol-2-ylidene)-1,3-dihydro- chemical structure, C16H10N2O2, CAS 479-41-4
2H-Indol-2-one, 3-(1,3-dihydro-3-oxo-2H-indol-2-ylidene)-1,3-dihydro-
CAS 479-41-4C16H10N2O2
3-(1,3-Dihydro-3-oxo-2H-indol-2-ylidene)-1,3-dihydro-5-iodo-2H-indol-2-one chemical structure, C16H9IN2O2, CAS 126433-42-9
3-(1,3-Dihydro-3-oxo-2H-indol-2-ylidene)-1,3-dihydro-5-iodo-2H-indol-2-one
CAS 126433-42-9C16H9IN2O2
Antibiotic 79002 chemical structure, C18H14N2O2, CAS 82355-81-5
Antibiotic 79002
CAS 82355-81-5C18H14N2O2
Antibiotic 79005 chemical structure, C24H26N2O2, CAS 87496-48-8
Antibiotic 79005
CAS 87496-48-8C24H26N2O2
(2Z)-2-(5-Bromo-3H-indol-3-ylidene)-5-nitro-1,2-dihydro-3H-indol-3-one chemical structure, C16H8BrN3O3, CAS 94028-68-9
(2Z)-2-(5-Bromo-3H-indol-3-ylidene)-5-nitro-1,2-dihydro-3H-indol-3-one
CAS 94028-68-9C16H8BrN3O3
5-Bromo-2-(5-bromo-1H-indol-3-yl)indol-3-one chemical structure, C16H8Br2N2O, CAS 92797-11-0
5-Bromo-2-(5-bromo-1H-indol-3-yl)indol-3-one
CAS 92797-11-0C16H8Br2N2O
3H-Indol-3-one, 5-bromo-2-(1H-indol-3-yl)- chemical structure, C16H9BrN2O, CAS 92967-81-2
3H-Indol-3-one, 5-bromo-2-(1H-indol-3-yl)-
CAS 92967-81-2C16H9BrN2O
5'-Fluoro-[2,3'-biindolinylidene]-2',3-dione chemical structure, C16H9FN2O2, CAS 251903-00-1
5'-Fluoro-[2,3'-biindolinylidene]-2',3-dione
CAS 251903-00-1C16H9FN2O2
5-Bromoindirubin chemical structure, C16H9BrN2O2, CAS 60874-72-8
5-Bromoindirubin
CAS 60874-72-8C16H9BrN2O2
6-Bromo-2-[(3Z)-6-bromo-2-oxo-2,3-dihydro-1H-indol-3-ylidene]-2,3-dihydro-1H-indol-3-one chemical structure, C16H8Br2N2O2, CAS 667463-97-0
6-Bromo-2-[(3Z)-6-bromo-2-oxo-2,3-dihydro-1H-indol-3-ylidene]-2,3-dihydro-1H-indol-3-one
CAS 667463-97-0C16H8Br2N2O2
2'-(Methoxyamino)-1'-methyl-1'H,3H-(2,3'-biindol)-3-one chemical structure, C18H15N3O2, CAS 82371-94-6
2'-(Methoxyamino)-1'-methyl-1'H,3H-(2,3'-biindol)-3-one
CAS 82371-94-6C18H15N3O2
Indirubin deriv. 12a chemical structure, C16H9BrN2O2, CAS 667463-65-2
Indirubin deriv. 12a
CAS 667463-65-2C16H9BrN2O2
(Z)-5',6'-Dichloro-[2,3'-biindolinylidene]-2',3-dione chemical structure, C16H8Cl2N2O2, CAS 667463-72-1
(Z)-5',6'-Dichloro-[2,3'-biindolinylidene]-2',3-dione
CAS 667463-72-1C16H8Cl2N2O2
1,3-Dihydro-1-acetyl-3-(1,3-dihydro-3-oxo-2H-indol-2-ylidene)-2H-indol-2-one chemical structure, C18H12N2O3, CAS 82349-12-0
1,3-Dihydro-1-acetyl-3-(1,3-dihydro-3-oxo-2H-indol-2-ylidene)-2H-indol-2-one
CAS 82349-12-0C18H12N2O3
(2''Z)-7-Bromo-5-nitroindirubin chemical structure, C16H8BrN3O4, CAS 1191245-20-1
(2''Z)-7-Bromo-5-nitroindirubin
CAS 1191245-20-1C16H8BrN3O4