CompoundList
Sign in
Murcko scaffold

Ring system with 4 rings and 19 atoms

91 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
19
Chemicals
91
With full pages
16
Scaffold SMILES

O=[PH]1OCC2OC(n3cnc4cncnc43)CC2O1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=[PH]1OCC2OC(n3cnc4cncnc43)CC2O1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 91 chemicals

Acrasin chemical structure, C10H12N5O6P, CAS 85187-54-8
Acrasin
CAS 85187-54-8C10H12N5O6P
6-[6-Amino-8-(sulfanylmethyl)purin-9-yl]-2-hydroxy-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-ol chemical structure, C11H14N5O6PS, CAS 61866-10-2
6-[6-Amino-8-(sulfanylmethyl)purin-9-yl]-2-hydroxy-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-ol
CAS 61866-10-2C11H14N5O6PS
Camp chemical structure, C10H12N5O6P, CAS 60-92-4
Camp
CAS 60-92-4C10H12N5O6P
Bucladesine chemical structure, C18H24N5O8P, CAS 362-74-3
Bucladesine
CAS 362-74-3C18H24N5O8P
8-Bromo-cAMP chemical structure, C10H11BrN5O6P, CAS 23583-48-4
8-Bromo-cAMP
CAS 23583-48-4C10H11BrN5O6P
Tocladesine chemical structure, C10H11ClN5O6P, CAS 41941-56-4
Tocladesine
CAS 41941-56-4C10H11ClN5O6P
Adenosine, N-(1-oxobutyl)-, cyclic 3',5'-(hydrogen phosphate) chemical structure, C14H18N5O7P, CAS 13117-60-7
Adenosine, N-(1-oxobutyl)-, cyclic 3',5'-(hydrogen phosphate)
CAS 13117-60-7C14H18N5O7P
8-Azidoadenosine-3',5'-monophosphate chemical structure, C10H11N8O6P, CAS 31966-52-6
8-Azidoadenosine-3',5'-monophosphate
CAS 31966-52-6C10H11N8O6P
8-Aminohexylamino cAMP chemical structure, C16H26N7O6P, CAS 39824-30-1
8-Aminohexylamino cAMP
CAS 39824-30-1C16H26N7O6P
Adenosine, cyclic 3',5'-(hydrogen phosphate) 2'-(hydrogen butanedioate) chemical structure, C14H16N5O9P, CAS 36940-87-1
Adenosine, cyclic 3',5'-(hydrogen phosphate) 2'-(hydrogen butanedioate)
CAS 36940-87-1C14H16N5O9P
8-((4-Bromo-2,3-dioxobutyl)thio)-adenosine 3',5'-cyclic monophosphate chemical structure, C14H15BrN5O8PS, CAS 124357-34-2
8-((4-Bromo-2,3-dioxobutyl)thio)-adenosine 3',5'-cyclic monophosphate
CAS 124357-34-2C14H15BrN5O8PS
Adenosine, cyclic 3',5'-(hydrogen phosphate) 2'-butanoate chemical structure, C14H18N5O7P, CAS 15392-98-0
Adenosine, cyclic 3',5'-(hydrogen phosphate) 2'-butanoate
CAS 15392-98-0C14H18N5O7P
Adenosine, 8-amino-, cyclic 3',5'-(hydrogen phosphate) chemical structure, C10H13N6O6P, CAS 30685-40-6
Adenosine, 8-amino-, cyclic 3',5'-(hydrogen phosphate)
CAS 30685-40-6C10H13N6O6P
N(1),O(2)-Dioctanoyl cyclic amp chemical structure, C26H40N5O8P, CAS 57329-09-6
N(1),O(2)-Dioctanoyl cyclic amp
CAS 57329-09-6C26H40N5O8P
3',5'-Cyclic dAMP chemical structure, C10H12N5O5P, CAS 1157-33-1
3',5'-Cyclic dAMP
CAS 1157-33-1C10H12N5O5P
8-Hydroxyethylaminoadenosine 3',5'-monophosphate chemical structure, C12H17N6O7P, CAS 33823-17-5
8-Hydroxyethylaminoadenosine 3',5'-monophosphate
CAS 33823-17-5C12H17N6O7P
N(6)-Monobutyryl-2'-deoxycyclic adenosine monophosphate chemical structure, C14H18N5O6P, CAS 61866-09-9
N(6)-Monobutyryl-2'-deoxycyclic adenosine monophosphate
CAS 61866-09-9C14H18N5O6P
N(6),O(2)-Dipivaloyl cyclic amp chemical structure, C20H28N5O8P, CAS 78232-35-6
N(6),O(2)-Dipivaloyl cyclic amp
CAS 78232-35-6C20H28N5O8P
N(6)-(ethyl-2-diazomalonyl)adenosine 3'-5'-cyclic monophosphate chemical structure, C15H16N7O9P, CAS 33904-28-8
N(6)-(ethyl-2-diazomalonyl)adenosine 3'-5'-cyclic monophosphate
CAS 33904-28-8C15H16N7O9P
2-Hydroxy-6-(6-methylsulfanylpurin-9-yl)-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinine 2-oxide chemical structure, C11H13N4O5PS, CAS 23526-12-7
2-Hydroxy-6-(6-methylsulfanylpurin-9-yl)-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinine 2-oxide
CAS 23526-12-7C11H13N4O5PS
6-(6-Amino-9H-purin-9-yl)-7-hydroxy-2-methoxytetrahydro-2H,4H-2lambda~5~-furo[3,2-d][1,3,2]dioxaphosphinin-2-one chemical structure, C11H14N5O6P, CAS 58937-08-9
6-(6-Amino-9H-purin-9-yl)-7-hydroxy-2-methoxytetrahydro-2H,4H-2lambda~5~-furo[3,2-d][1,3,2]dioxaphosphinin-2-one
CAS 58937-08-9C11H14N5O6P
6-(6,8-Diaminopurin-9-yl)-2-hydroxy-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-ol chemical structure, C10H13N6O6P, CAS 56973-14-9
6-(6,8-Diaminopurin-9-yl)-2-hydroxy-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-ol
CAS 56973-14-9C10H13N6O6P
Butyryl Cyclic AMP chemical structure, C14H18N5O7P, CAS 34675-98-4
Butyryl Cyclic AMP
CAS 34675-98-4C14H18N5O7P
Cyclic ara-AMP chemical structure, C10H12N5O6P, CAS 32465-18-2
Cyclic ara-AMP
CAS 32465-18-2C10H12N5O6P