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Murcko scaffold

Ring system with 3 rings and 23 atoms

19 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
23
Chemicals
19
With full pages
5
Scaffold SMILES

c1ccc(CNCCC(c2ccccc2)C2CCOCC2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(CNCCC(c2ccccc2)C2CCOCC2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 19 of 19 chemicals

N-[(3,4-Dimethoxyphenyl)methyl]-N-[3-(2,2-dimethyloxan-4-yl)-3-phenylpropyl]acetamide chemical structure, C27H37NO4, CAS 337487-11-3
N-[(3,4-Dimethoxyphenyl)methyl]-N-[3-(2,2-dimethyloxan-4-yl)-3-phenylpropyl]acetamide
CAS 337487-11-3C27H37NO4
N-[3-(2,2-Dimethyloxan-4-yl)-3-(2-methoxyphenyl)propyl]-N-[(4-methoxyphenyl)methyl]acetamide chemical structure, C27H37NO4, CAS 5936-31-2
N-[3-(2,2-Dimethyloxan-4-yl)-3-(2-methoxyphenyl)propyl]-N-[(4-methoxyphenyl)methyl]acetamide
CAS 5936-31-2C27H37NO4
N-[3-(2,2-Dimethyloxan-4-yl)-3-(4-methoxyphenyl)propyl]-N-[(4-methoxyphenyl)methyl]acetamide chemical structure, C27H37NO4, CAS 337486-75-6
N-[3-(2,2-Dimethyloxan-4-yl)-3-(4-methoxyphenyl)propyl]-N-[(4-methoxyphenyl)methyl]acetamide
CAS 337486-75-6C27H37NO4
3-(2,2-Dimethyltetrahydro-2H-pyran-4-yl)-N-(4-methoxybenzyl)-3-phenylpropan-1-amine chemical structure, C24H33NO2, CAS 337486-86-9
3-(2,2-Dimethyltetrahydro-2H-pyran-4-yl)-N-(4-methoxybenzyl)-3-phenylpropan-1-amine
CAS 337486-86-9C24H33NO2
N-[3-(2,2-Dimethyloxan-4-yl)-3-phenylpropyl]-N-[(4-methoxyphenyl)methyl]propanamide chemical structure, C27H37NO3, CAS 337486-97-2
N-[3-(2,2-Dimethyloxan-4-yl)-3-phenylpropyl]-N-[(4-methoxyphenyl)methyl]propanamide
CAS 337486-97-2C27H37NO3
N-Benzyl-N-[3-(2,2-dimethyloxan-4-yl)-3-phenylpropyl]propanamide chemical structure, C26H35NO2, CAS 337487-01-1
N-Benzyl-N-[3-(2,2-dimethyloxan-4-yl)-3-phenylpropyl]propanamide
CAS 337487-01-1C26H35NO2
N-[(3,4-Dimethoxyphenyl)methyl]-N-[3-(2,2-dimethyloxan-4-yl)-3-phenylpropyl]propanamide chemical structure, C28H39NO4, CAS 337486-48-3
N-[(3,4-Dimethoxyphenyl)methyl]-N-[3-(2,2-dimethyloxan-4-yl)-3-phenylpropyl]propanamide
CAS 337486-48-3C28H39NO4
N-[3-(2,2-Dimethyloxan-4-yl)-3-(2-methoxyphenyl)propyl]-N-[(4-methoxyphenyl)methyl]propanamide chemical structure, C28H39NO4, CAS 337486-51-8
N-[3-(2,2-Dimethyloxan-4-yl)-3-(2-methoxyphenyl)propyl]-N-[(4-methoxyphenyl)methyl]propanamide
CAS 337486-51-8C28H39NO4
N-[3-(2,2-Dimethyloxan-4-yl)-3-phenylpropyl]-N-[(4-methoxyphenyl)methyl]acetamide chemical structure, C26H35NO3, CAS 337486-88-1
N-[3-(2,2-Dimethyloxan-4-yl)-3-phenylpropyl]-N-[(4-methoxyphenyl)methyl]acetamide
CAS 337486-88-1C26H35NO3
N-Benzyl-N-[3-(2,2-dimethyloxan-4-yl)-3-phenylpropyl]acetamide chemical structure, C25H33NO2, CAS 337486-90-5
N-Benzyl-N-[3-(2,2-dimethyloxan-4-yl)-3-phenylpropyl]acetamide
CAS 337486-90-5C25H33NO2
3-(2-Ethyl-2-methyloxan-4-yl)-N-[(4-fluorophenyl)methyl]-3-(4-methylphenyl)propan-1-amine chemical structure, C25H34FNO, CAS 472984-54-6
3-(2-Ethyl-2-methyloxan-4-yl)-N-[(4-fluorophenyl)methyl]-3-(4-methylphenyl)propan-1-amine
CAS 472984-54-6C25H34FNO
N-Benzyl-3-(2,2-dimethyloxan-4-yl)-3-(4-methoxyphenyl)propan-1-amine chemical structure, C24H33NO2, CAS 428828-73-3
N-Benzyl-3-(2,2-dimethyloxan-4-yl)-3-(4-methoxyphenyl)propan-1-amine
CAS 428828-73-3C24H33NO2
N-[4-(Dimethylamino)benzyl]-N-[3-(2,2-dimethyltetrahydro-2H-pyran-4-yl)-3-(2-methoxyphenyl)propyl]acetamide chemical structure, C28H40N2O3, CAS 309741-12-6
N-[4-(Dimethylamino)benzyl]-N-[3-(2,2-dimethyltetrahydro-2H-pyran-4-yl)-3-(2-methoxyphenyl)propyl]acetamide
CAS 309741-12-6C28H40N2O3
N-(4-(Dimethylamino)benzyl)-N-(3-(2,2-dimethyltetrahydro-2H-pyran-4-yl)-3-(4-methoxyphenyl)propyl)acetamide chemical structure, C28H40N2O3, CAS 428850-89-9
N-(4-(Dimethylamino)benzyl)-N-(3-(2,2-dimethyltetrahydro-2H-pyran-4-yl)-3-(4-methoxyphenyl)propyl)acetamide
CAS 428850-89-9C28H40N2O3
4-[[[3-(2,2-Dimethyloxan-4-yl)-3-(2-methoxyphenyl)propyl]amino]methyl]-N,N-dimethylaniline chemical structure, C26H38N2O2, CAS 429624-98-6
4-[[[3-(2,2-Dimethyloxan-4-yl)-3-(2-methoxyphenyl)propyl]amino]methyl]-N,N-dimethylaniline
CAS 429624-98-6C26H38N2O2
N-Benzyl-3-(2,2-dimethyloxan-4-yl)-3-(2-methoxyphenyl)propan-1-amine chemical structure, C24H33NO2, CAS 429622-29-7
N-Benzyl-3-(2,2-dimethyloxan-4-yl)-3-(2-methoxyphenyl)propan-1-amine
CAS 429622-29-7C24H33NO2
N-[3-(2,2-Dimethyloxan-4-yl)-3-phenylpropyl]-N-(1-phenylethyl)propanamide chemical structure, C27H37NO2, CAS 473801-50-2
N-[3-(2,2-Dimethyloxan-4-yl)-3-phenylpropyl]-N-(1-phenylethyl)propanamide
CAS 473801-50-2C27H37NO2
3-(2,2-Dimethyloxan-4-yl)-3-phenyl-N-(1-phenylethyl)propan-1-amine chemical structure, C24H33NO, CAS 473800-49-6
3-(2,2-Dimethyloxan-4-yl)-3-phenyl-N-(1-phenylethyl)propan-1-amine
CAS 473800-49-6C24H33NO
4-[[[3-(2,2-Dimethyloxan-4-yl)-3-(4-methoxyphenyl)propyl]amino]methyl]-N,N-dimethylaniline chemical structure, C26H38N2O2, CAS 428504-94-3
4-[[[3-(2,2-Dimethyloxan-4-yl)-3-(4-methoxyphenyl)propyl]amino]methyl]-N,N-dimethylaniline
CAS 428504-94-3C26H38N2O2