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Murcko scaffold

Ring system with 3 rings and 24 atoms

20 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
24
Chemicals
20
With full pages
8
Scaffold SMILES

O=C(NCC(c1ccccc1)N1CCNCC1)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NCC(c1ccccc1)N1CCNCC1)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 20 of 20 chemicals

1-(1-(4-Methylpiperazin-1-yl)-1-phenylpropan-2-yl)-3-phenylurea chemical structure, C21H28N4O, CAS 868228-39-1
1-(1-(4-Methylpiperazin-1-yl)-1-phenylpropan-2-yl)-3-phenylurea
CAS 868228-39-1C21H28N4O
1-(3-Chlorophenyl)-3-(1-(4-methylpiperazin-1-yl)-1-phenylpropan-2-yl)urea chemical structure, C21H27ClN4O, CAS 868228-51-7
1-(3-Chlorophenyl)-3-(1-(4-methylpiperazin-1-yl)-1-phenylpropan-2-yl)urea
CAS 868228-51-7C21H27ClN4O
1-(1-(4-Methylpiperazin-1-yl)-1-phenylpropan-2-yl)-3-(m-tolyl)urea chemical structure, C22H30N4O, CAS 868228-57-3
1-(1-(4-Methylpiperazin-1-yl)-1-phenylpropan-2-yl)-3-(m-tolyl)urea
CAS 868228-57-3C22H30N4O
1-(2-(4-Methoxyphenyl)-2-(4-methylpiperazin-1-yl)ethyl)-3-phenylurea chemical structure, C21H28N4O2, CAS 898448-40-3
1-(2-(4-Methoxyphenyl)-2-(4-methylpiperazin-1-yl)ethyl)-3-phenylurea
CAS 898448-40-3C21H28N4O2
1-(2-(4-Methoxyphenyl)-2-(4-methylpiperazin-1-yl)ethyl)-3-(m-tolyl)urea chemical structure, C22H30N4O2, CAS 898448-42-5
1-(2-(4-Methoxyphenyl)-2-(4-methylpiperazin-1-yl)ethyl)-3-(m-tolyl)urea
CAS 898448-42-5C22H30N4O2
1-(3-Methylphenyl)-3-[2-(4-methylphenyl)-2-(4-methylpiperazin-1-yl)ethyl]urea chemical structure, C22H30N4O, CAS 898414-47-6
1-(3-Methylphenyl)-3-[2-(4-methylphenyl)-2-(4-methylpiperazin-1-yl)ethyl]urea
CAS 898414-47-6C22H30N4O
1-(4-Chlorophenyl)-3-[2-(4-methoxyphenyl)-2-(4-methylpiperazin-1-yl)ethyl]urea chemical structure, C21H27ClN4O2, CAS 898430-49-4
1-(4-Chlorophenyl)-3-[2-(4-methoxyphenyl)-2-(4-methylpiperazin-1-yl)ethyl]urea
CAS 898430-49-4C21H27ClN4O2
1-(4-Chlorophenyl)-3-[2-(4-fluorophenyl)-2-(4-methylpiperazin-1-yl)ethyl]urea chemical structure, C20H24ClFN4O, CAS 898448-52-7
1-(4-Chlorophenyl)-3-[2-(4-fluorophenyl)-2-(4-methylpiperazin-1-yl)ethyl]urea
CAS 898448-52-7C20H24ClFN4O
1-(2-(4-Fluorophenyl)-2-(4-methylpiperazin-1-yl)ethyl)-3-(m-tolyl)urea chemical structure, C21H27FN4O, CAS 898430-61-0
1-(2-(4-Fluorophenyl)-2-(4-methylpiperazin-1-yl)ethyl)-3-(m-tolyl)urea
CAS 898430-61-0C21H27FN4O
1-(2-(4-Methylpiperazin-1-yl)-2-(p-tolyl)ethyl)-3-phenylurea chemical structure, C21H28N4O, CAS 898448-70-9
1-(2-(4-Methylpiperazin-1-yl)-2-(p-tolyl)ethyl)-3-phenylurea
CAS 898448-70-9C21H28N4O
1-(4-Chlorophenyl)-3-(2-(4-methylpiperazin-1-yl)-2-(p-tolyl)ethyl)urea chemical structure, C21H27ClN4O, CAS 898414-46-5
1-(4-Chlorophenyl)-3-(2-(4-methylpiperazin-1-yl)-2-(p-tolyl)ethyl)urea
CAS 898414-46-5C21H27ClN4O
1-(2-(4-(Dimethylamino)phenyl)-2-(4-methylpiperazin-1-yl)ethyl)-3-(p-tolyl)urea chemical structure, C23H33N5O, CAS 1170242-44-0
1-(2-(4-(Dimethylamino)phenyl)-2-(4-methylpiperazin-1-yl)ethyl)-3-(p-tolyl)urea
CAS 1170242-44-0C23H33N5O
1-(2-(4-(Dimethylamino)phenyl)-2-(4-methylpiperazin-1-yl)ethyl)-3-(4-fluorophenyl)urea chemical structure, C22H30FN5O, CAS 848769-39-1
1-(2-(4-(Dimethylamino)phenyl)-2-(4-methylpiperazin-1-yl)ethyl)-3-(4-fluorophenyl)urea
CAS 848769-39-1C22H30FN5O
1-(2-(4-(Dimethylamino)phenyl)-2-(4-methylpiperazin-1-yl)ethyl)-3-(3-methoxyphenyl)urea chemical structure, C23H33N5O2, CAS 1170442-46-2
1-(2-(4-(Dimethylamino)phenyl)-2-(4-methylpiperazin-1-yl)ethyl)-3-(3-methoxyphenyl)urea
CAS 1170442-46-2C23H33N5O2
1-(5-Chloro-2-methoxyphenyl)-3-(2-(4-(dimethylamino)phenyl)-2-(4-methylpiperazin-1-yl)ethyl)urea chemical structure, C23H32ClN5O2, CAS 1171464-38-2
1-(5-Chloro-2-methoxyphenyl)-3-(2-(4-(dimethylamino)phenyl)-2-(4-methylpiperazin-1-yl)ethyl)urea
CAS 1171464-38-2C23H32ClN5O2
1-{2-[4-(Dimethylamino)phenyl]-2-(4-methylpiperazin-1-yl)ethyl}-3-(2-methoxyphenyl)urea chemical structure, C23H33N5O2, CAS 1172972-78-9
1-{2-[4-(Dimethylamino)phenyl]-2-(4-methylpiperazin-1-yl)ethyl}-3-(2-methoxyphenyl)urea
CAS 1172972-78-9C23H33N5O2
1-(2-(4-(Dimethylamino)phenyl)-2-(4-methylpiperazin-1-yl)ethyl)-3-(2-ethoxyphenyl)urea chemical structure, C24H35N5O2, CAS 1170656-76-4
1-(2-(4-(Dimethylamino)phenyl)-2-(4-methylpiperazin-1-yl)ethyl)-3-(2-ethoxyphenyl)urea
CAS 1170656-76-4C24H35N5O2
1-(3,5-Dimethoxyphenyl)-3-(2-(4-(dimethylamino)phenyl)-2-(4-methylpiperazin-1-yl)ethyl)urea chemical structure, C24H35N5O3, CAS 1172971-45-7
1-(3,5-Dimethoxyphenyl)-3-(2-(4-(dimethylamino)phenyl)-2-(4-methylpiperazin-1-yl)ethyl)urea
CAS 1172971-45-7C24H35N5O3
1-(4-Butoxyphenyl)-3-{2-[4-(dimethylamino)phenyl]-2-(4-methylpiperazin-1-yl)ethyl}urea chemical structure, C26H39N5O2, CAS 1171397-75-3
1-(4-Butoxyphenyl)-3-{2-[4-(dimethylamino)phenyl]-2-(4-methylpiperazin-1-yl)ethyl}urea
CAS 1171397-75-3C26H39N5O2
1-(2,3-Dimethoxyphenyl)-3-(2-(4-(dimethylamino)phenyl)-2-(4-methylpiperazin-1-yl)ethyl)urea chemical structure, C24H35N5O3, CAS 1171600-48-8
1-(2,3-Dimethoxyphenyl)-3-(2-(4-(dimethylamino)phenyl)-2-(4-methylpiperazin-1-yl)ethyl)urea
CAS 1171600-48-8C24H35N5O3