CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 24 atoms

9 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
24
Chemicals
9
With full pages
2
Scaffold SMILES

O=C(NCCc1ccccc1)C(c1ccccc1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NCCc1ccccc1)C(c1ccccc1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

N-[2-(3,4-Dimethoxyphenyl)ethyl]-2,2-diphenylacetamide chemical structure, C24H25NO3, CAS 30488-64-3
N-[2-(3,4-Dimethoxyphenyl)ethyl]-2,2-diphenylacetamide
CAS 30488-64-3C24H25NO3
Methyl 2-[(2,2-diphenylacetyl)amino]-3-phenylpropanoate chemical structure, C24H23NO3, CAS 7621-95-6
Methyl 2-[(2,2-diphenylacetyl)amino]-3-phenylpropanoate
CAS 7621-95-6C24H23NO3
N-[2-(3-Chlorophenyl)ethyl]-2,2-diphenylacetamide chemical structure, C22H20ClNO, CAS 540531-77-9
N-[2-(3-Chlorophenyl)ethyl]-2,2-diphenylacetamide
CAS 540531-77-9C22H20ClNO
(2S)-2-(2,2-Diphenylacetamido)-3-phenylpropanoic acid chemical structure, C23H21NO3, CAS 65707-84-8
(2S)-2-(2,2-Diphenylacetamido)-3-phenylpropanoic acid
CAS 65707-84-8C23H21NO3
N-[2-(3-Butoxy-4-methoxyphenyl)ethyl]-2,2-diphenylacetamide chemical structure, C27H31NO3, CAS 312269-30-0
N-[2-(3-Butoxy-4-methoxyphenyl)ethyl]-2,2-diphenylacetamide
CAS 312269-30-0C27H31NO3
N-[2-(4-Ethoxy-3-methoxyphenyl)ethyl]-2,2-diphenylacetamide chemical structure, C25H27NO3, CAS 30488-65-4
N-[2-(4-Ethoxy-3-methoxyphenyl)ethyl]-2,2-diphenylacetamide
CAS 30488-65-4C25H27NO3
2-(2,2-Diphenylacetamido)-3-phenylpropanoic acid chemical structure, C23H21NO3, CAS 65707-83-7
2-(2,2-Diphenylacetamido)-3-phenylpropanoic acid
CAS 65707-83-7C23H21NO3
N-(2-Hydroxy-2-(4-(trifluoromethyl)phenyl)ethyl)-2,2-diphenylacetamide chemical structure, C23H20F3NO2, CAS 1351659-92-1
N-(2-Hydroxy-2-(4-(trifluoromethyl)phenyl)ethyl)-2,2-diphenylacetamide
CAS 1351659-92-1C23H20F3NO2
Methyl N-(diphenylacetyl)-2-hydroxyphenylalaninate chemical structure, C24H23NO4, CAS 194795-21-6
Methyl N-(diphenylacetyl)-2-hydroxyphenylalaninate
CAS 194795-21-6C24H23NO4