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Murcko scaffold

Ring system with 2 rings and 10 atoms

27 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
27
With full pages
10
Scaffold SMILES

O=C1O[IH]c2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1O[IH]c2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 27 of 27 chemicals

1-Hydroxy-1,2-benziodoxol-3(1H)-one chemical structure, C7H5IO3, CAS 131-62-4
1-Hydroxy-1,2-benziodoxol-3(1H)-one
CAS 131-62-4C7H5IO3
Triacetoxyperiodinane chemical structure, C13H13IO8, CAS 87413-09-0
Triacetoxyperiodinane
CAS 87413-09-0C13H13IO8
1-Chloro-1,2-benziodoxol-3(1H)-one chemical structure, C7H4ClIO2, CAS 59457-26-0
1-Chloro-1,2-benziodoxol-3(1H)-one
CAS 59457-26-0C7H4ClIO2
1-Fluoro-1,2-benziodoxol-3(1H)-one chemical structure, C7H4FIO2, CAS 1022643-48-6
1-Fluoro-1,2-benziodoxol-3(1H)-one
CAS 1022643-48-6C7H4FIO2
1-Azido-1,2-benziodoxol-3(1H)-one chemical structure, C7H4IN3O2, CAS 160732-56-9
1-Azido-1,2-benziodoxol-3(1H)-one
CAS 160732-56-9C7H4IN3O2
3-Oxo-3H-1lambda3,2-benziodaoxole-1-carbonitrile chemical structure, C8H4INO2, CAS 172876-96-9
3-Oxo-3H-1lambda3,2-benziodaoxole-1-carbonitrile
CAS 172876-96-9C8H4INO2
1-[3,3-Dimethylbutynyl]-1,2-benziodoxol-3(1H)-one chemical structure, C13H13IO2, CAS 135226-09-4
1-[3,3-Dimethylbutynyl]-1,2-benziodoxol-3(1H)-one
CAS 135226-09-4C13H13IO2
1-Acetoxy-1,2-benziodoxol-3-one chemical structure, C9H7IO4, CAS 1829-26-1
1-Acetoxy-1,2-benziodoxol-3-one
CAS 1829-26-1C9H7IO4
1-[(Trimethylsilyl)ethynyl]-1,2-benziodoxol-3(1H)-one chemical structure, C12H13IO2Si, CAS 181934-29-2
1-[(Trimethylsilyl)ethynyl]-1,2-benziodoxol-3(1H)-one
CAS 181934-29-2C12H13IO2Si
1-((Triisopropylsilyl)ethynyl)-1,2-benziodoxol-3(1H)-one chemical structure, C18H25IO2Si, CAS 181934-30-5
1-((Triisopropylsilyl)ethynyl)-1,2-benziodoxol-3(1H)-one
CAS 181934-30-5C18H25IO2Si
1-(tert-Butylperoxy)-1,2-benziodoxol-3(1H)-one chemical structure, C11H13IO4, CAS 142260-70-6
1-(tert-Butylperoxy)-1,2-benziodoxol-3(1H)-one
CAS 142260-70-6C11H13IO4
1-Methoxy-1,2-benziodoxol-3-(1H)-one chemical structure, C8H7IO3, CAS 1829-25-0
1-Methoxy-1,2-benziodoxol-3-(1H)-one
CAS 1829-25-0C8H7IO3
4,5,6,7-Tetrafluoro-1-hydroxy-1,2-benziodoxole-3(1H)-one chemical structure, C7HF4IO3, CAS 954373-94-5
4,5,6,7-Tetrafluoro-1-hydroxy-1,2-benziodoxole-3(1H)-one
CAS 954373-94-5C7HF4IO3
1-Trifluoromethyl-1,2-benziodoxol-3(1H)-one chemical structure, C8H4F3IO2, CAS 887144-94-7
1-Trifluoromethyl-1,2-benziodoxol-3(1H)-one
CAS 887144-94-7C8H4F3IO2
1-Acetoxy-5-bromo-1,2-benziodoxol-3(1H)-one chemical structure, C9H6BrIO4, CAS 1580548-81-7
1-Acetoxy-5-bromo-1,2-benziodoxol-3(1H)-one
CAS 1580548-81-7C9H6BrIO4
5-Nitro-1-(trifluoromethyl)-3H-1On3,2-benziodaoxol-3-one chemical structure, C8H3F3INO4, CAS 1627706-08-4
5-Nitro-1-(trifluoromethyl)-3H-1On3,2-benziodaoxol-3-one
CAS 1627706-08-4C8H3F3INO4
Ethynyl-1,2-benziodoxol-3(1H)-one chemical structure, C9H5IO2, CAS 1252671-79-6
Ethynyl-1,2-benziodoxol-3(1H)-one
CAS 1252671-79-6C9H5IO2
1-(1,1,2,2,2-Pentafluoroethyl)-3H-1lambda3,2-benziodaoxol-3-one chemical structure, C9H4F5IO2, CAS 1401714-42-8
1-(1,1,2,2,2-Pentafluoroethyl)-3H-1lambda3,2-benziodaoxol-3-one
CAS 1401714-42-8C9H4F5IO2
1-Hydroxy-5-methoxy-3H-1lambda3,2-benziodaoxol-3-one chemical structure, C8H7IO4, CAS 105933-66-2
1-Hydroxy-5-methoxy-3H-1lambda3,2-benziodaoxol-3-one
CAS 105933-66-2C8H7IO4
5-Methyl-1-(trifluoromethyl)-1lambda3,2-benziodoxol-3-one chemical structure, C9H6F3IO2, CAS 1888292-74-7
5-Methyl-1-(trifluoromethyl)-1lambda3,2-benziodoxol-3-one
CAS 1888292-74-7C9H6F3IO2
1-Isoperfluoropropyl-1,2-benziodoxol-3-(1H)-one chemical structure, C10H4F7IO2, CAS 2851842-48-1
1-Isoperfluoropropyl-1,2-benziodoxol-3-(1H)-one
CAS 2851842-48-1C10H4F7IO2
3H-1,2-Benziodoxole-5-carbonitrile, 3-oxo-1-(trifluoromethyl)- chemical structure, C9H3F3INO2, CAS 1888292-79-2
3H-1,2-Benziodoxole-5-carbonitrile, 3-oxo-1-(trifluoromethyl)-
CAS 1888292-79-2C9H3F3INO2
3H-1,2-Benziodoxol-3-one, 1,5-bis(trifluoromethyl)- chemical structure, C9H3F6IO2, CAS 1888292-78-1
3H-1,2-Benziodoxol-3-one, 1,5-bis(trifluoromethyl)-
CAS 1888292-78-1C9H3F6IO2
3H-1,2-Benziodoxol-3-one, 5-bromo-1-(trifluoromethyl)- chemical structure, C8H3BrF3IO2, CAS 1888292-77-0
3H-1,2-Benziodoxol-3-one, 5-bromo-1-(trifluoromethyl)-
CAS 1888292-77-0C8H3BrF3IO2