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Murcko scaffold

Ring system with 4 rings and 29 atoms

17 chemicals on CompoundList share this ring system.

Rings: 4
Scaffold atoms: 29
Chemicals: 17
With full pages: 1

Scaffold SMILES

O=C(CCCn1c(=O)[nH]c2ccccc2c1=O)N1CCN(c2ccccc2)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=C(CCCn1c(=O)[nH]c2ccccc2c1=O)N1CCN(c2ccccc2)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 17 of 17 chemicals

6-Bromo-3-[4-[4-(4-fluorophenyl)piperazin-1-yl]-4-oxobutyl]-1H-quinazoline-2,4-dione chemical structure, C22H22BrFN4O3, CAS 1022252-61-4

6-Bromo-3-[4-[4-(4-fluorophenyl)piperazin-1-yl]-4-oxobutyl]-1H-quinazoline-2,4-dione

CAS 1022252-61-4C₂₂H₂₂BrFN₄O₃

3-[4-[4-(3-Chlorophenyl)piperazin-1-yl]-4-oxobutyl]-1H-quinazoline-2,4-dione chemical structure, C22H23ClN4O3, CAS 896373-63-0

3-[4-[4-(3-Chlorophenyl)piperazin-1-yl]-4-oxobutyl]-1H-quinazoline-2,4-dione

CAS 896373-63-0C₂₂H₂₃ClN₄O₃

3-[4-[4-(2,5-Dimethylphenyl)piperazin-1-yl]-4-oxobutyl]-1H-quinazoline-2,4-dione chemical structure, C24H28N4O3, CAS 896373-79-8

3-[4-[4-(2,5-Dimethylphenyl)piperazin-1-yl]-4-oxobutyl]-1H-quinazoline-2,4-dione

CAS 896373-79-8C₂₄H₂₈N₄O₃

3-[4-[4-(4-Fluorophenyl)piperazin-1-yl]-4-oxobutyl]-1H-quinazoline-2,4-dione chemical structure, C22H23FN4O3, CAS 896373-57-2

3-[4-[4-(4-Fluorophenyl)piperazin-1-yl]-4-oxobutyl]-1H-quinazoline-2,4-dione

CAS 896373-57-2C₂₂H₂₃FN₄O₃

6-Bromo-3-(4-(4-(3-chlorophenyl)piperazin-1-yl)-4-oxobutyl)quinazoline-2,4(1H,3H)-dione chemical structure, C22H22BrClN4O3, CAS 892286-72-5

6-Bromo-3-(4-(4-(3-chlorophenyl)piperazin-1-yl)-4-oxobutyl)quinazoline-2,4(1H,3H)-dione

CAS 892286-72-5C₂₂H₂₂BrClN₄O₃

6-Bromo-3-(4-(4-(5-chloro-2-methylphenyl)piperazin-1-yl)-4-oxobutyl)quinazoline-2,4(1H,3H)-dione chemical structure, C23H24BrClN4O3, CAS 892287-33-1

6-Bromo-3-(4-(4-(5-chloro-2-methylphenyl)piperazin-1-yl)-4-oxobutyl)quinazoline-2,4(1H,3H)-dione

CAS 892287-33-1C₂₃H₂₄BrClN₄O₃

6-Bromo-3-(4-(4-(3-methoxyphenyl)piperazin-1-yl)-4-oxobutyl)quinazoline-2,4(1H,3H)-dione chemical structure, C23H25BrN4O4, CAS 892287-41-1

6-Bromo-3-(4-(4-(3-methoxyphenyl)piperazin-1-yl)-4-oxobutyl)quinazoline-2,4(1H,3H)-dione

CAS 892287-41-1C₂₃H₂₅BrN₄O₄

3-(4-(4-(4-Nitrophenyl)piperazin-1-yl)-4-oxobutyl)quinazoline-2,4(1H,3H)-dione chemical structure, C22H23N5O5, CAS 896373-88-9

3-(4-(4-(4-Nitrophenyl)piperazin-1-yl)-4-oxobutyl)quinazoline-2,4(1H,3H)-dione

CAS 896373-88-9C₂₂H₂₃N₅O₅

6-Bromo-3-(4-(4-(2,3-dimethylphenyl)piperazin-1-yl)-4-oxobutyl)quinazoline-2,4(1H,3H)-dione chemical structure, C24H27BrN4O3, CAS 892287-09-1

6-Bromo-3-(4-(4-(2,3-dimethylphenyl)piperazin-1-yl)-4-oxobutyl)quinazoline-2,4(1H,3H)-dione

CAS 892287-09-1C₂₄H₂₇BrN₄O₃

6-Bromo-3-(4-(3-methyl-4-(m-tolyl)piperazin-1-yl)-4-oxobutyl)quinazoline-2,4(1H,3H)-dione chemical structure, C24H27BrN4O3, CAS 892287-25-1

6-Bromo-3-(4-(3-methyl-4-(m-tolyl)piperazin-1-yl)-4-oxobutyl)quinazoline-2,4(1H,3H)-dione

CAS 892287-25-1C₂₄H₂₇BrN₄O₃

3-{4-[4-(4-Acetylphenyl)piperazin-1-yl]-4-oxobutyl}quinazoline-2,4(1H,3H)-dione chemical structure, C24H26N4O4, CAS 896373-76-5

3-{4-[4-(4-Acetylphenyl)piperazin-1-yl]-4-oxobutyl}quinazoline-2,4(1H,3H)-dione

CAS 896373-76-5C₂₄H₂₆N₄O₄

6-Bromo-3-(4-(4-(2-methoxyphenyl)piperazin-1-yl)-4-oxobutyl)quinazoline-2,4(1H,3H)-dione chemical structure, C23H25BrN4O4, CAS 892286-79-2

6-Bromo-3-(4-(4-(2-methoxyphenyl)piperazin-1-yl)-4-oxobutyl)quinazoline-2,4(1H,3H)-dione

CAS 892286-79-2C₂₃H₂₅BrN₄O₄

6-Bromo-3-(4-(4-(4-chlorophenyl)piperazin-1-yl)-4-oxobutyl)quinazoline-2,4(1H,3H)-dione chemical structure, C22H22BrClN4O3, CAS 892287-17-1

6-Bromo-3-(4-(4-(4-chlorophenyl)piperazin-1-yl)-4-oxobutyl)quinazoline-2,4(1H,3H)-dione

CAS 892287-17-1C₂₂H₂₂BrClN₄O₃

3-{4-[4-(4-Acetylphenyl)piperazin-1-yl]-4-oxobutyl}-6-bromoquinazoline-2,4(1H,3H)-dione chemical structure, C24H25BrN4O4, CAS 892287-01-3

3-{4-[4-(4-Acetylphenyl)piperazin-1-yl]-4-oxobutyl}-6-bromoquinazoline-2,4(1H,3H)-dione

CAS 892287-01-3C₂₄H₂₅BrN₄O₄

3-(4-(4-(2-Methoxyphenyl)piperazin-1-yl)-4-oxobutyl)quinazoline-2,4(1H,3H)-dione chemical structure, C23H26N4O4, CAS 896373-69-6

3-(4-(4-(2-Methoxyphenyl)piperazin-1-yl)-4-oxobutyl)quinazoline-2,4(1H,3H)-dione

CAS 896373-69-6C₂₃H₂₆N₄O₄

6-Bromo-3-(4-oxo-4-(4-phenylpiperazin-1-yl)butyl)quinazoline-2,4(1H,3H)-dione chemical structure, C22H23BrN4O3, CAS 892286-58-7

6-Bromo-3-(4-oxo-4-(4-phenylpiperazin-1-yl)butyl)quinazoline-2,4(1H,3H)-dione

CAS 892286-58-7C₂₂H₂₃BrN₄O₃

3-(4-(4-(3-Methoxyphenyl)piperazin-1-yl)-4-oxobutyl)quinazoline-2,4(1H,3H)-dione chemical structure, C23H26N4O4, CAS 896373-85-6

3-(4-(4-(3-Methoxyphenyl)piperazin-1-yl)-4-oxobutyl)quinazoline-2,4(1H,3H)-dione

CAS 896373-85-6C₂₃H₂₆N₄O₄