CompoundList
Sign in
Murcko scaffold

5-Oxo-N-phenylpyrrolidine-2-carboxamide scaffold

42 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
15
Chemicals
42
With full pages
9
Scaffold SMILES

O=C1CCC(C(=O)Nc2ccccc2)N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 5-Oxo-N-phenylpyrrolidine-2-carboxamide page
Murcko scaffold O=C1CCC(C(=O)Nc2ccccc2)N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 42 of 42 chemicals

Pyroglutamine-4-nitroanilide chemical structure, C11H11N3O4, CAS 66642-35-1
Pyroglutamine-4-nitroanilide
CAS 66642-35-1C11H11N3O4
5-Oxo-N-phenylpyrrolidine-2-carboxamide chemical structure, C11H12N2O2, CAS 5626-54-0
5-Oxo-N-phenylpyrrolidine-2-carboxamide
CAS 5626-54-0C11H12N2O2
N-(3,4-Dichlorophenyl)-5-oxoprolinamide chemical structure, C11H10Cl2N2O2, CAS 4108-15-0
N-(3,4-Dichlorophenyl)-5-oxoprolinamide
CAS 4108-15-0C11H10Cl2N2O2
N-(2,4-Dichlorophenyl)-5-oxopyrrolidine-2-carboxamide chemical structure, C11H10Cl2N2O2, CAS 4255-83-8
N-(2,4-Dichlorophenyl)-5-oxopyrrolidine-2-carboxamide
CAS 4255-83-8C11H10Cl2N2O2
N-Mesityl-5-oxo-2-pyrrolidinecarboxamide chemical structure, C14H18N2O2, CAS 498558-70-6
N-Mesityl-5-oxo-2-pyrrolidinecarboxamide
CAS 498558-70-6C14H18N2O2
(2R)-5-Oxo-N-phenyl-2-pyrrolidinecarboxamide chemical structure, C11H12N2O2, CAS 68295-46-5
(2R)-5-Oxo-N-phenyl-2-pyrrolidinecarboxamide
CAS 68295-46-5C11H12N2O2
2-Pyrrolidinecarboxamide, 5-oxo-N-phenyl-, (2S)- chemical structure, C11H12N2O2, CAS 68295-47-6
2-Pyrrolidinecarboxamide, 5-oxo-N-phenyl-, (2S)-
CAS 68295-47-6C11H12N2O2
(2S)-5-Oxo-N-(4-propan-2-ylphenyl)pyrrolidine-2-carboxamide chemical structure, C14H18N2O2, CAS 471915-73-8
(2S)-5-Oxo-N-(4-propan-2-ylphenyl)pyrrolidine-2-carboxamide
CAS 471915-73-8C14H18N2O2
N-(4-Methoxyphenyl)-5-oxopyrrolidine-2-carboxamide chemical structure, C12H14N2O3, CAS 4108-09-2
N-(4-Methoxyphenyl)-5-oxopyrrolidine-2-carboxamide
CAS 4108-09-2C12H14N2O3
N-(2-Methoxyphenyl)-5-oxopyrrolidine-2-carboxamide chemical structure, C12H14N2O3, CAS 459147-82-1
N-(2-Methoxyphenyl)-5-oxopyrrolidine-2-carboxamide
CAS 459147-82-1C12H14N2O3
5-Oxo-pyrrolidine-2-carboxylic acid o-tolylamide chemical structure, C12H14N2O2, CAS 4193-42-4
5-Oxo-pyrrolidine-2-carboxylic acid o-tolylamide
CAS 4193-42-4C12H14N2O2
N-(3,4-Dimethylphenyl)-5-oxoprolinamide chemical structure, C13H16N2O2, CAS 302809-22-9
N-(3,4-Dimethylphenyl)-5-oxoprolinamide
CAS 302809-22-9C13H16N2O2
N-(4-Chlorophenyl)-5-oxopyrrolidine-2-carboxamide chemical structure, C11H11ClN2O2, CAS 4108-12-7
N-(4-Chlorophenyl)-5-oxopyrrolidine-2-carboxamide
CAS 4108-12-7C11H11ClN2O2
N-(3-Bromophenyl)-5-oxopyrrolidine-2-carboxamide chemical structure, C11H11BrN2O2, CAS 471290-59-2
N-(3-Bromophenyl)-5-oxopyrrolidine-2-carboxamide
CAS 471290-59-2C11H11BrN2O2
5-Oxo-N-[3-(trifluoromethyl)phenyl]prolinamide chemical structure, C12H11F3N2O2, CAS 499191-63-8
5-Oxo-N-[3-(trifluoromethyl)phenyl]prolinamide
CAS 499191-63-8C12H11F3N2O2
N-(3,5-Dimethylphenyl)-5-oxopyrrolidine-2-carboxamide chemical structure, C13H16N2O2, CAS 1008201-89-5
N-(3,5-Dimethylphenyl)-5-oxopyrrolidine-2-carboxamide
CAS 1008201-89-5C13H16N2O2
N-(5-Chloro-2-methylphenyl)-5-oxo-2-pyrrolidinecarboxamide chemical structure, C12H13ClN2O2, CAS 1008480-29-2
N-(5-Chloro-2-methylphenyl)-5-oxo-2-pyrrolidinecarboxamide
CAS 1008480-29-2C12H13ClN2O2
5-Oxo-pyrrolidine-2-carboxylic acid m-tolylamide chemical structure, C12H14N2O2, CAS 5082-56-4
5-Oxo-pyrrolidine-2-carboxylic acid m-tolylamide
CAS 5082-56-4C12H14N2O2
N-(4-Iodophenyl)-5-oxopyrrolidine-2-carboxamide chemical structure, C11H11IN2O2, CAS 1009500-34-8
N-(4-Iodophenyl)-5-oxopyrrolidine-2-carboxamide
CAS 1009500-34-8C11H11IN2O2
N-(4-Fluorophenyl)-5-oxo-2-pyrrolidinecarboxamide chemical structure, C11H11FN2O2, CAS 1219391-40-8
N-(4-Fluorophenyl)-5-oxo-2-pyrrolidinecarboxamide
CAS 1219391-40-8C11H11FN2O2
N-(4-Ethylphenyl)-5-oxopyrrolidine-2-carboxamide chemical structure, C13H16N2O2, CAS 1008480-25-8
N-(4-Ethylphenyl)-5-oxopyrrolidine-2-carboxamide
CAS 1008480-25-8C13H16N2O2
N-(4-Bromophenyl)-5-oxo-2-pyrrolidinecarboxamide chemical structure, C11H11BrN2O2, CAS 1219388-16-5
N-(4-Bromophenyl)-5-oxo-2-pyrrolidinecarboxamide
CAS 1219388-16-5C11H11BrN2O2
5-Oxo-N-(p-tolyl)pyrrolidine-2-carboxamide chemical structure, C12H14N2O2, CAS 4108-07-0
5-Oxo-N-(p-tolyl)pyrrolidine-2-carboxamide
CAS 4108-07-0C12H14N2O2
N-(4-Ethoxyphenyl)-5-oxo-2-pyrrolidinecarboxamide chemical structure, C13H16N2O3, CAS 4108-14-9
N-(4-Ethoxyphenyl)-5-oxo-2-pyrrolidinecarboxamide
CAS 4108-14-9C13H16N2O3