CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 16 atoms

31 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
31
With full pages
5
Scaffold SMILES

c1ccc(-c2ccnc3c2CCCC3)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(-c2ccnc3c2CCCC3)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 31 of 31 chemicals

2-Amino-4-(3-ethoxy-4-hydroxyphenyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile chemical structure, C18H19N3O2, CAS 332018-47-0
2-Amino-4-(3-ethoxy-4-hydroxyphenyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile
CAS 332018-47-0C18H19N3O2
2-Amino-4-(4-methoxyphenyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile chemical structure, C17H17N3O, CAS 74873-46-4
2-Amino-4-(4-methoxyphenyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile
CAS 74873-46-4C17H17N3O
2-Amino-4-(4-chlorophenyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile chemical structure, C16H14ClN3, CAS 164026-59-9
2-Amino-4-(4-chlorophenyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile
CAS 164026-59-9C16H14ClN3
2-Amino-4-phenyl-5,6,7,8-tetrahydroquinoline-3-carbonitrile chemical structure, C16H15N3, CAS 5272-37-7
2-Amino-4-phenyl-5,6,7,8-tetrahydroquinoline-3-carbonitrile
CAS 5272-37-7C16H15N3
2-Amino-4-(3,4-dimethoxyphenyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile chemical structure, C18H19N3O2, CAS 170940-62-2
2-Amino-4-(3,4-dimethoxyphenyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile
CAS 170940-62-2C18H19N3O2
4-(4-Hydroxyphenyl)-2-(methylsulfanyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile chemical structure, C17H16N2OS, CAS 312604-12-9
4-(4-Hydroxyphenyl)-2-(methylsulfanyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile
CAS 312604-12-9C17H16N2OS
2-Amino-4-(4-methylphenyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile chemical structure, C17H17N3, CAS 74873-43-1
2-Amino-4-(4-methylphenyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile
CAS 74873-43-1C17H17N3
Methyl {[3-cyano-4-(4-hydroxyphenyl)-5,6,7,8-tetrahydro-2-quinolinyl]thio}acetate chemical structure, C19H18N2O3S, CAS 313550-91-3
Methyl {[3-cyano-4-(4-hydroxyphenyl)-5,6,7,8-tetrahydro-2-quinolinyl]thio}acetate
CAS 313550-91-3C19H18N2O3S
Methyl [(3-cyano-4-phenyl-5,6,7,8-tetrahydroquinolin-2-yl)sulfanyl]acetate chemical structure, C19H18N2O2S, CAS 94833-82-6
Methyl [(3-cyano-4-phenyl-5,6,7,8-tetrahydroquinolin-2-yl)sulfanyl]acetate
CAS 94833-82-6C19H18N2O2S
2-Amino-6-(tert-butyl)-4-(3-ethoxy-4-hydroxyphenyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile chemical structure, C22H27N3O2, CAS 247592-55-8
2-Amino-6-(tert-butyl)-4-(3-ethoxy-4-hydroxyphenyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile
CAS 247592-55-8C22H27N3O2
2-Amino-6-(tert-butyl)-4-(3,4-dimethoxyphenyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile chemical structure, C22H27N3O2, CAS 332127-26-1
2-Amino-6-(tert-butyl)-4-(3,4-dimethoxyphenyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile
CAS 332127-26-1C22H27N3O2
2-Amino-8-methyl-4-phenyl-5,6,7,8-tetrahydroquinoline-3-carbonitrile chemical structure, C17H17N3, CAS 331979-92-1
2-Amino-8-methyl-4-phenyl-5,6,7,8-tetrahydroquinoline-3-carbonitrile
CAS 331979-92-1C17H17N3
2-Amino-4-(4-methoxyphenyl)-8-methyl-5,6,7,8-tetrahydroquinoline-3-carbonitrile chemical structure, C18H19N3O, CAS 331979-97-6
2-Amino-4-(4-methoxyphenyl)-8-methyl-5,6,7,8-tetrahydroquinoline-3-carbonitrile
CAS 331979-97-6C18H19N3O
2-Amino-6-tert-butyl-4-(4-nitrophenyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile chemical structure, C20H22N4O2, CAS 514220-73-6
2-Amino-6-tert-butyl-4-(4-nitrophenyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile
CAS 514220-73-6C20H22N4O2
2-Amino-4-(2-chlorophenyl)-6-ethyl-5,6,7,8-tetrahydroquinoline-3-carbonitrile chemical structure, C18H18ClN3, CAS 361198-25-6
2-Amino-4-(2-chlorophenyl)-6-ethyl-5,6,7,8-tetrahydroquinoline-3-carbonitrile
CAS 361198-25-6C18H18ClN3
2-(Butylsulfanyl)-4-(4-chlorophenyl)-5,6,7,8-tetrahydro-3-quinolinecarbonitrile chemical structure, C20H21ClN2S, CAS 135747-36-3
2-(Butylsulfanyl)-4-(4-chlorophenyl)-5,6,7,8-tetrahydro-3-quinolinecarbonitrile
CAS 135747-36-3C20H21ClN2S
2-Methyl-4-phenyl-5,6,7,8-tetrahydroquinoline-8-carbothioamide chemical structure, C17H18N2S, CAS 56717-30-7
2-Methyl-4-phenyl-5,6,7,8-tetrahydroquinoline-8-carbothioamide
CAS 56717-30-7C17H18N2S
2-Chloro-4-phenyl-5,6,7,8-tetrahydroquinoline chemical structure, C15H14ClN, CAS 132813-02-6
2-Chloro-4-phenyl-5,6,7,8-tetrahydroquinoline
CAS 132813-02-6C15H14ClN
2-Chloro-4-phenyl-5,6,7,8-tetrahydroquinoline-3-carbonitrile chemical structure, C16H13ClN2, CAS 1132758-35-0
2-Chloro-4-phenyl-5,6,7,8-tetrahydroquinoline-3-carbonitrile
CAS 1132758-35-0C16H13ClN2
4-(4-Methylphenyl)-2-(propylsulfanyl)-5,6,7,8-tetrahydro-3-quinolinecarbonitrile chemical structure, C20H22N2S, CAS 2061759-54-2
4-(4-Methylphenyl)-2-(propylsulfanyl)-5,6,7,8-tetrahydro-3-quinolinecarbonitrile
CAS 2061759-54-2C20H22N2S
2-Chloro-4-(2-fluorophenyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile chemical structure, C16H12ClFN2, CAS 1225701-60-9
2-Chloro-4-(2-fluorophenyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile
CAS 1225701-60-9C16H12ClFN2
2-Chloro-4-(4-fluorophenyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile chemical structure, C16H12ClFN2, CAS 1225701-69-8
2-Chloro-4-(4-fluorophenyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile
CAS 1225701-69-8C16H12ClFN2
2-Chloro-4-(2-chlorophenyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile chemical structure, C16H12Cl2N2, CAS 1225857-59-9
2-Chloro-4-(2-chlorophenyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile
CAS 1225857-59-9C16H12Cl2N2
2-Chloro-4-(3-chlorophenyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile chemical structure, C16H12Cl2N2, CAS 1226396-35-5
2-Chloro-4-(3-chlorophenyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile
CAS 1226396-35-5C16H12Cl2N2