Murcko scaffold
2-(4-Oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)-N-phenylacetamide scaffold
252 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 26
- Chemicals
- 252
- With full pages
- 3
Scaffold SMILES
O=C(Cn1cnc2c(-c3ccccc3)csc2c1=O)Nc1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 252 chemicals
![N-(3-Fluoro-4-methylphenyl)-2-(4-oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)acetamide chemical structure, C21H16FN3O2S, CAS 1105234-95-4](/s/KJEUHSDFCLAGOI-UHFFFAOYSA-N.svg)
N-(3-Fluoro-4-methylphenyl)-2-(4-oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)acetamide
CAS 1105234-95-4C21H16FN3O2S
![N-(5-Fluoro-2-methylphenyl)-2-(4-oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)acetamide chemical structure, C21H16FN3O2S, CAS 1105223-59-3](/s/LBRJALPWJSDCME-UHFFFAOYSA-N.svg)
N-(5-Fluoro-2-methylphenyl)-2-(4-oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)acetamide
CAS 1105223-59-3C21H16FN3O2S
![N-(5-Chloro-2-methylphenyl)-2-(4-oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)acetamide chemical structure, C21H16ClN3O2S, CAS 1105235-01-5](/s/SVFZCLLCHLKQJC-UHFFFAOYSA-N.svg)
N-(5-Chloro-2-methylphenyl)-2-(4-oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)acetamide
CAS 1105235-01-5C21H16ClN3O2S
![N-(2-Chloro-4-methylphenyl)-2-(4-oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)acetamide chemical structure, C21H16ClN3O2S, CAS 1105223-65-1](/s/QZRFNYWDSNEQQY-UHFFFAOYSA-N.svg)
N-(2-Chloro-4-methylphenyl)-2-(4-oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)acetamide
CAS 1105223-65-1C21H16ClN3O2S
![N-(3-Chloro-4-methoxyphenyl)-2-(4-oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)acetamide chemical structure, C21H16ClN3O3S, CAS 1105235-07-1](/s/XBFVGJNVZBETOA-UHFFFAOYSA-N.svg)
N-(3-Chloro-4-methoxyphenyl)-2-(4-oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)acetamide
CAS 1105235-07-1C21H16ClN3O3S
![N-(5-Chloro-2,4-dimethoxyphenyl)-2-(4-oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)acetamide chemical structure, C22H18ClN3O4S, CAS 1105223-71-9](/s/ZKYQVBVCVQFZMS-UHFFFAOYSA-N.svg)
N-(5-Chloro-2,4-dimethoxyphenyl)-2-(4-oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)acetamide
CAS 1105223-71-9C22H18ClN3O4S
![N-(4-Fluorophenyl)-N-methyl-2-(4-oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)acetamide chemical structure, C21H16FN3O2S, CAS 1105235-14-0](/s/RGRJKFJNAQUSNI-UHFFFAOYSA-N.svg)
N-(4-Fluorophenyl)-N-methyl-2-(4-oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)acetamide
CAS 1105235-14-0C21H16FN3O2S
![2-(4-Oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)-N-phenylacetamide chemical structure, C20H15N3O2S, CAS 1105223-77-5](/s/DOPUDJYMQFJCLS-UHFFFAOYSA-N.svg)
2-(4-Oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)-N-phenylacetamide
CAS 1105223-77-5C20H15N3O2S
![N-(4-Methylphenyl)-2-(4-oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)acetamide chemical structure, C21H17N3O2S, CAS 1105235-21-9](/s/OTDKZGIMYKFYCG-UHFFFAOYSA-N.svg)
N-(4-Methylphenyl)-2-(4-oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)acetamide
CAS 1105235-21-9C21H17N3O2S
![N-(2,4-Dimethylphenyl)-2-(4-oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)acetamide chemical structure, C22H19N3O2S, CAS 1105223-83-3](/s/PNYBTZQCGNCYBC-UHFFFAOYSA-N.svg)
N-(2,4-Dimethylphenyl)-2-(4-oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)acetamide
CAS 1105223-83-3C22H19N3O2S
![N-(2,5-Dimethylphenyl)-2-(4-oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)acetamide chemical structure, C22H19N3O2S, CAS 1105235-28-6](/s/JSCSEQOVOBJZRP-UHFFFAOYSA-N.svg)
N-(2,5-Dimethylphenyl)-2-(4-oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)acetamide
CAS 1105235-28-6C22H19N3O2S
![N-(2,6-Dimethylphenyl)-2-(4-oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)acetamide chemical structure, C22H19N3O2S, CAS 1105223-88-8](/s/UVFXRFNASSCTRB-UHFFFAOYSA-N.svg)
N-(2,6-Dimethylphenyl)-2-(4-oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)acetamide
CAS 1105223-88-8C22H19N3O2S
![N-(4-Ethylphenyl)-2-(4-oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)acetamide chemical structure, C22H19N3O2S, CAS 1105235-36-6](/s/DEBHCUICEPXUQZ-UHFFFAOYSA-N.svg)
N-(4-Ethylphenyl)-2-(4-oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)acetamide
CAS 1105235-36-6C22H19N3O2S
![N-(2-Ethyl-6-methylphenyl)-2-(4-oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)acetamide chemical structure, C23H21N3O2S, CAS 1105223-93-5](/s/XNOLUFQUEOECNW-UHFFFAOYSA-N.svg)
N-(2-Ethyl-6-methylphenyl)-2-(4-oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)acetamide
CAS 1105223-93-5C23H21N3O2S
![N-(4-Butylphenyl)-2-(4-oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)acetamide chemical structure, C24H23N3O2S, CAS 1105235-44-6](/s/XGHUHNXOUAJEEZ-UHFFFAOYSA-N.svg)
N-(4-Butylphenyl)-2-(4-oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)acetamide
CAS 1105235-44-6C24H23N3O2S
![N-Methyl-2-(4-oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)-N-phenylacetamide chemical structure, C21H17N3O2S, CAS 1105223-98-0](/s/BBYLXQGIRIAGFN-UHFFFAOYSA-N.svg)
N-Methyl-2-(4-oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)-N-phenylacetamide
CAS 1105223-98-0C21H17N3O2S
![N-Ethyl-2-(4-oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)-N-phenylacetamide chemical structure, C22H19N3O2S, CAS 1105235-52-6](/s/NVINKJSWJWMAKE-UHFFFAOYSA-N.svg)
N-Ethyl-2-(4-oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)-N-phenylacetamide
CAS 1105235-52-6C22H19N3O2S
![N-(2-Methoxyphenyl)-2-(4-oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)acetamide chemical structure, C21H17N3O3S, CAS 1105224-04-1](/s/ZWAPXIROEBZAJU-UHFFFAOYSA-N.svg)
N-(2-Methoxyphenyl)-2-(4-oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)acetamide
CAS 1105224-04-1C21H17N3O3S
![N-(3-Methoxyphenyl)-2-(4-oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)acetamide chemical structure, C21H17N3O3S, CAS 1105235-60-6](/s/SWMFVAPFAUTKSP-UHFFFAOYSA-N.svg)
N-(3-Methoxyphenyl)-2-(4-oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)acetamide
CAS 1105235-60-6C21H17N3O3S
![N-(4-Methoxyphenyl)-2-(4-oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)acetamide chemical structure, C21H17N3O3S, CAS 1105224-10-9](/s/GKTGRWICSFTRNZ-UHFFFAOYSA-N.svg)
N-(4-Methoxyphenyl)-2-(4-oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)acetamide
CAS 1105224-10-9C21H17N3O3S
![N-(2,5-Dimethoxyphenyl)-2-(4-oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)acetamide chemical structure, C22H19N3O4S, CAS 1105235-68-4](/s/KHFJAUYTOIVANJ-UHFFFAOYSA-N.svg)
N-(2,5-Dimethoxyphenyl)-2-(4-oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)acetamide
CAS 1105235-68-4C22H19N3O4S
![N-(2-Ethoxyphenyl)-2-(4-oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)acetamide chemical structure, C22H19N3O3S, CAS 1105224-16-5](/s/SOUXRGTXYCHDQV-UHFFFAOYSA-N.svg)
N-(2-Ethoxyphenyl)-2-(4-oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)acetamide
CAS 1105224-16-5C22H19N3O3S
![N-(4-Ethoxyphenyl)-2-(4-oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)acetamide chemical structure, C22H19N3O3S, CAS 1105235-76-4](/s/VZHNBWSVTQVCQC-UHFFFAOYSA-N.svg)
N-(4-Ethoxyphenyl)-2-(4-oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)acetamide
CAS 1105235-76-4C22H19N3O3S
![N-[3-(Methylthio)phenyl]-2-(4-oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)acetamide chemical structure, C21H17N3O2S2, CAS 1105235-84-4](/s/CRCIXGSMKIGPPP-UHFFFAOYSA-N.svg)
N-[3-(Methylthio)phenyl]-2-(4-oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)acetamide
CAS 1105235-84-4C21H17N3O2S2
- N-(2-Methoxy-5-methylphenyl)-2-(4-oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)acetamide1105235-92-4C22H19N3O3S
- Methyl 2-{[(4-oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)acetyl]amino}benzoate1105224-33-6C22H17N3O4S
- Ethyl 3-{[(4-oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)acetyl]amino}benzoate1105236-00-7C23H19N3O4S
- Methyl 4-(2-{4-oxo-7-phenyl-3H,4H-thieno[3,2-d]pyrimidin-3-yl}acetamido)benzoate1105224-38-1C22H17N3O4S
- Ethyl 4-{[(4-oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)acetyl]amino}benzoate1105236-08-5C23H19N3O4S
- N-[4-(Acetylamino)phenyl]-2-(4-oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)acetamide1105224-43-8C22H18N4O3S
- N-(2-Fluorophenyl)-2-(4-oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)acetamide1105235-24-2C20H14FN3O2S
- N-(3-Fluorophenyl)-2-(4-oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)acetamide1105207-08-6C20H14FN3O2S
- N-(4-Fluorophenyl)-2-(4-oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)acetamide1105235-31-1C20H14FN3O2S
- N-(2-Chlorophenyl)-2-(4-oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)acetamide1105207-13-3C20H14ClN3O2S
- N-(4-Chlorophenyl)-2-(4-oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)acetamide1105235-39-9C20H14ClN3O2S
- N-(3-Bromophenyl)-2-(4-oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)acetamide1105207-18-8C20H14BrN3O2S
- N-(4-Bromophenyl)-2-(4-oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)acetamide1105235-47-9C20H14BrN3O2S
- N-(2-Chloro-4-fluorophenyl)-2-(4-oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)acetamide1105207-23-5C20H13ClFN3O2S
- N-(4-Bromo-2-fluorophenyl)-2-(4-oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)acetamide1105235-55-9C20H13BrFN3O2S
- N-(3-Chloro-2-methylphenyl)-2-(4-oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)acetamide1105207-28-0C21H16ClN3O2S
- N-[2-Chloro-5-(trifluoromethyl)phenyl]-2-(4-oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)acetamide1105235-63-9C21H13ClF3N3O2S
- N-[4-Chloro-3-(trifluoromethyl)phenyl]-2-(4-oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)acetamide1105207-34-8C21H13ClF3N3O2S
- N-(2-Methylphenyl)-2-(4-oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)acetamide1105235-71-9C21H17N3O2S
- N-(3-Methylphenyl)-2-(4-oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)acetamide1105207-40-6C21H17N3O2S
- N-(3,4-Dimethylphenyl)-2-(4-oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)acetamide1105235-79-7C22H19N3O2S
- N-(3,5-Dimethylphenyl)-2-(4-oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)acetamide1105207-46-2C22H19N3O2S
- N-Mesityl-2-(4-oxo-7-phenylthieno[3,2-d]pyrimidin-3(4H)-yl)acetamide1105235-87-7C23H21N3O2S
- N-(2-Ethylphenyl)-2-{4-oxo-7-phenyl-3H,4H-thieno[3,2-d]pyrimidin-3-yl}acetamide1105207-52-0C22H19N3O2S
Related scaffolds
Same ring framework with different atoms or bond orders
O=C(Cn1cnc2c(cnn2-c2ccccc2)c1=O)Nc1ccccc19 chemicals
O=C(Cn1cnc2c(nnn2-c2ccccc2)c1=O)Nc1ccccc14 chemicals
O=C(Cn1cnc2c(cnn2-c2ccccc2)c1=O)NC1CCCCC13 chemicals
O=c1c2nnn(-c3ccccc3)c2ncn1CC=Cc1ccccc12 chemicals
O=C(NCc1ccccc1)c1ccc2c(c1)ncn2-c1ccccc12 chemicals![Scaffold O=C(CSc1nc2scc(-c3ccccc3)c2c(=O)[nH]1)c1ccccc1](/scaffold/GQVOPKFMIZCLDD-UHFFFAOYSA-N/structure.svg)
O=C(CSc1nc2scc(-c3ccccc3)c2c(=O)[nH]1)c1ccccc11 chemical![Scaffold [N+]=C1C=C(c2ccccc2)c2ccc(OCCN3CCOCC3)cc21](/scaffold/QDWMHUIRPWEKET-UHFFFAOYSA-N/structure.svg)
[N+]=C1C=C(c2ccccc2)c2ccc(OCCN3CCOCC3)cc211 chemical