CompoundList
Sign in
Murcko scaffold

2-[(2-Oxo-2-phenylethyl)sulfanyl]-5-phenyl-3H,4H-thieno[2,3-d]pyrimidin-4-one scaffold

9 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
26
Chemicals
9
With full pages
1
Scaffold SMILES

O=C(CSc1nc2scc(-c3ccccc3)c2c(=O)[nH]1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-[(2-Oxo-2-phenylethyl)sulfanyl]-5-phenyl-3H,4H-thieno[2,3-d]pyrimidin-4-one page
Murcko scaffold O=C(CSc1nc2scc(-c3ccccc3)c2c(=O)[nH]1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

2-[(2-Oxo-2-phenylethyl)sulfanyl]-5-phenyl-3H,4H-thieno[2,3-d]pyrimidin-4-one chemical structure, C20H14N2O2S2, CAS 304683-67-8
2-[(2-Oxo-2-phenylethyl)sulfanyl]-5-phenyl-3H,4H-thieno[2,3-d]pyrimidin-4-one
CAS 304683-67-8C20H14N2O2S2
2-[2-(4-Methoxyphenyl)-2-oxoethyl]sulfanyl-5-phenyl-3-prop-2-enylthieno[2,3-d]pyrimidin-4-one chemical structure, C24H20N2O3S2, CAS 315710-44-2
2-[2-(4-Methoxyphenyl)-2-oxoethyl]sulfanyl-5-phenyl-3-prop-2-enylthieno[2,3-d]pyrimidin-4-one
CAS 315710-44-2C24H20N2O3S2
5-(4-Fluorophenyl)-2-phenacylsulfanyl-3-prop-2-enylthieno[2,3-d]pyrimidin-4-one chemical structure, C23H17FN2O2S2, CAS 379248-12-1
5-(4-Fluorophenyl)-2-phenacylsulfanyl-3-prop-2-enylthieno[2,3-d]pyrimidin-4-one
CAS 379248-12-1C23H17FN2O2S2
2-{[2-(4-Chlorophenyl)-2-oxoethyl]sulfanyl}-5-(4-fluorophenyl)-3-(prop-2-en-1-yl)thieno[2,3-d]pyrimidin-4(3H)-one chemical structure, C23H16ClFN2O2S2, CAS 496023-34-8
2-{[2-(4-Chlorophenyl)-2-oxoethyl]sulfanyl}-5-(4-fluorophenyl)-3-(prop-2-en-1-yl)thieno[2,3-d]pyrimidin-4(3H)-one
CAS 496023-34-8C23H16ClFN2O2S2
3-Allyl-2-((2-(4-fluorophenyl)-2-oxoethyl)thio)-5-phenylthieno[2,3-d]pyrimidin-4(3H)-one chemical structure, C23H17FN2O2S2, CAS 446852-14-8
3-Allyl-2-((2-(4-fluorophenyl)-2-oxoethyl)thio)-5-phenylthieno[2,3-d]pyrimidin-4(3H)-one
CAS 446852-14-8C23H17FN2O2S2
3-Allyl-2-((2-(4-(tert-butyl)phenyl)-2-oxoethyl)thio)-5-(4-fluorophenyl)thieno[2,3-d]pyrimidin-4(3H)-one chemical structure, C27H25FN2O2S2, CAS 670268-40-3
3-Allyl-2-((2-(4-(tert-butyl)phenyl)-2-oxoethyl)thio)-5-(4-fluorophenyl)thieno[2,3-d]pyrimidin-4(3H)-one
CAS 670268-40-3C27H25FN2O2S2
2-[2-(3,4-Dichlorophenyl)-2-oxoethyl]sulfanyl-5-(4-methylphenyl)-3-prop-2-enylthieno[2,3-d]pyrimidin-4-one chemical structure, C24H18Cl2N2O2S2, CAS 671200-58-1
2-[2-(3,4-Dichlorophenyl)-2-oxoethyl]sulfanyl-5-(4-methylphenyl)-3-prop-2-enylthieno[2,3-d]pyrimidin-4-one
CAS 671200-58-1C24H18Cl2N2O2S2
2-[2-(4-tert-Butylphenyl)-2-oxoethyl]sulfanyl-5-phenyl-3-prop-2-enylthieno[2,3-d]pyrimidin-4-one chemical structure, C27H26N2O2S2, CAS 690643-41-5
2-[2-(4-tert-Butylphenyl)-2-oxoethyl]sulfanyl-5-phenyl-3-prop-2-enylthieno[2,3-d]pyrimidin-4-one
CAS 690643-41-5C27H26N2O2S2
2-[2-(3,4-Dimethylphenyl)-2-oxoethyl]sulfanyl-5-phenyl-3-prop-2-enylthieno[2,3-d]pyrimidin-4-one chemical structure, C25H22N2O2S2, CAS 690643-44-8
2-[2-(3,4-Dimethylphenyl)-2-oxoethyl]sulfanyl-5-phenyl-3-prop-2-enylthieno[2,3-d]pyrimidin-4-one
CAS 690643-44-8C25H22N2O2S2