Murcko scaffold
3-Cyclobutylpyrrolidine scaffold
102 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 9
- Chemicals
- 102
- With full pages
- 4
Scaffold SMILES
C1CC(C2CCNC2)C1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 102 chemicals
tert-Butyl (1-(pyrrolidin-3-yl)cyclobutyl)carbamate
CAS 1330765-24-6C13H24N2O2
3-Cyclobutylpyrrolidine
CAS 1337336-36-3C8H15N
tert-Butyl 3-(2-aminocyclobutyl)pyrrolidine-1-carboxylate
CAS 1823264-88-5C13H24N2O2
tert-Butyl 3-(2-hydroxycyclobutyl)pyrrolidine-1-carboxylate
CAS 1823256-64-9C13H23NO3
![3-[1-(Aminomethyl)cyclobutyl]pyrrolidin-3-ol chemical structure, C9H18N2O, CAS 1505858-73-0](/s/JGCGJUCOWLIICA-UHFFFAOYSA-N.svg)
3-[1-(Aminomethyl)cyclobutyl]pyrrolidin-3-ol
CAS 1505858-73-0C9H18N2O
![3-[1-(Aminomethyl)cyclobutyl]-1-methylpyrrolidin-3-ol chemical structure, C10H20N2O, CAS 1532759-89-9](/s/CWFSTIRBBTTZST-UHFFFAOYSA-N.svg)
3-[1-(Aminomethyl)cyclobutyl]-1-methylpyrrolidin-3-ol
CAS 1532759-89-9C10H20N2O
3-Cyclobutylpyrrolidine-2-carboxylic acid
CAS 1517866-32-8C9H15NO2
3-(1-Ethylcyclobutyl)pyrrolidine
CAS 1544923-71-8C10H19N
4-Cyclobutyl-1-methylpyrrolidin-3-amine
CAS 1780509-34-3C9H18N2
1-(4-Cyclobutyl-1-methylpyrrolidin-3-yl)methanamine
CAS 1780802-47-2C10H20N2
tert-Butyl 3-amino-4-cyclobutylpyrrolidine-1-carboxylate
CAS 1779884-68-2C13H24N2O2
![tert-Butyl N-[(4-cyclobutylpyrrolidin-3-yl)methyl]carbamate chemical structure, C14H26N2O2, CAS 1782526-10-6](/s/ODNOJMLZBXBOTK-UHFFFAOYSA-N.svg)
tert-Butyl N-[(4-cyclobutylpyrrolidin-3-yl)methyl]carbamate
CAS 1782526-10-6C14H26N2O2
tert-Butyl 3-(aminomethyl)-4-cyclobutylpyrrolidine-1-carboxylate
CAS 1779898-57-5C14H26N2O2
![1-[(tert-Butoxy)carbonyl]-4-cyclobutylpyrrolidine-3-carboxylic acid chemical structure, C14H23NO4, CAS 1781134-50-6](/s/SRAURGNPYZWAPW-UHFFFAOYSA-N.svg)
1-[(tert-Butoxy)carbonyl]-4-cyclobutylpyrrolidine-3-carboxylic acid
CAS 1781134-50-6C14H23NO4
3-(1-Aminocyclobutyl)-1-pyrrolidinecarboxylic acid 1,1-dimethylethyl ester
CAS 1433638-70-0C13H24N2O2
Methyl 3-cyclobutylpyrrolidine-2-carboxylate
CAS 1779360-36-9C10H17NO2
4-Cyclobutylpyrrolidin-3-ol
CAS 1897759-98-6C8H15NO
1-((tert-Butoxy)carbonyl)-3-cyclobutylpyrrolidine-3-carboxylic acid
CAS 1700119-25-0C14H23NO4
3-Cyclobutylpyrrolidine-3-carboxylic acid
CAS 1601054-78-7C9H15NO2
3-Cyclobutylpyrrolidin-3-ol
CAS 1602822-74-1C8H15NO
3-Cyclobutylpyrrolidine hydrochloride
CAS 1955515-83-9C8H16ClN
Methyl 3-cyclobutylpyrrolidine-3-carboxylate
CAS 1823422-71-4C10H17NO2
1-(3-Cyclobutylpyrrolidin-1-yl)prop-2-en-1-one
CAS 2189893-34-1C11H17NO
Methyl 1-(3-hydroxypyrrolidin-3-yl)cyclobutane-1-carboxylate hydrochloride
CAS 2138534-25-3C10H18ClNO3
- Methyl 1-(3-hydroxypyrrolidin-3-yl)cyclobutane-1-carboxylate2138534-24-2C10H17NO3
- 1-{1-[(tert-Butoxy)carbonyl]-3-hydroxypyrrolidin-3-yl}cyclobutane-1-carboxylic acid2155854-92-3C14H23NO5
- 3-(3,3-Dimethoxycyclobutyl)pyrrolidine2287334-04-5C10H19NO2
- Methyl 3-cyclobutylpyrrolidine-3-carboxylate hydrochloride1823422-72-5C10H18ClNO2
- rac-(3R,4R)-1-[(tert-Butoxy)carbonyl]-4-[(1r,3S)-3-hydroxycyclobutyl]pyrrolidine-3-carboxylic acid2450757-96-5C14H23NO5
- 3-(3,3-Difluorocyclobutyl)pyrrolidine2228304-14-9C8H13F2N
- tert-Butyl 3-(3-aminocyclobutyl)pyrrolidine-1-carboxylate2356927-45-0C13H24N2O2
- rac-(3R,4S)-4-Cyclobutylpyrrolidin-3-ol2137829-20-8C8H15NO
- tert-Butyl 3-amino-3-(1-hydroxy-3,3-dimethylcyclobutyl)pyrrolidine-1-carboxylate2171703-12-9C15H28N2O3
- 1-[(tert-Butoxy)carbonyl]-3-cyclobutylpyrrolidine-2-carboxylic acid1822579-82-7C14H23NO4
- Methyl 1-(3-hydroxy-1-methylpyrrolidin-3-yl)-3-methoxycyclobutane-1-carboxylate2172446-54-5C12H21NO4
- tert-Butyl 3-hydroxy-3-[1-(hydroxymethyl)cyclobutyl]pyrrolidine-1-carboxylate2172019-49-5C14H25NO4
- 3-(1-Amino-3,3-dimethylcyclobutyl)-1-methylpyrrolidin-3-ol2171723-05-8C11H22N2O
- tert-Butyl 3-(1-hydroxycyclobutyl)-3-(hydroxymethyl)pyrrolidine-1-carboxylate2172258-00-1C14H25NO4
- Methyl 3,3-difluoro-1-(3-hydroxy-1-methylpyrrolidin-3-yl)cyclobutane-1-carboxylate2172010-57-8C11H17F2NO3
- tert-Butyl 3-(1-hydroxy-3,3-dimethylcyclobutyl)-3-(hydroxymethyl)pyrrolidine-1-carboxylate2172576-87-1C16H29NO4
- 1-(3-Hydroxy-1-methylpyrrolidin-3-yl)-3,3-dimethylcyclobutane-1-carboxylic acid2172570-50-0C12H21NO3
- Methyl 1-(3-hydroxy-1-methylpyrrolidin-3-yl)cyclobutane-1-carboxylate2171891-13-5C11H19NO3
- tert-Butyl 3-(1-amino-3,3-difluorocyclobutyl)-3-hydroxypyrrolidine-1-carboxylate2171647-57-5C13H22F2N2O3
- 1-[(tert-Butoxy)carbonyl]-3-(1-hydroxy-3,3-dimethylcyclobutyl)pyrrolidine-3-carboxylic acid2172578-68-4C16H27NO5
- 3,3-Difluoro-1-(3-hydroxy-1-methylpyrrolidin-3-yl)cyclobutane-1-carboxylic acid2172095-39-3C10H15F2NO3
- tert-Butyl 3-[3,3-difluoro-1-(hydroxymethyl)cyclobutyl]-3-hydroxypyrrolidine-1-carboxylate2172582-65-7C14H23F2NO4
- 1-(3-Hydroxy-1-methylpyrrolidin-3-yl)cyclobutane-1-carboxylic acid2172069-99-5C10H17NO3
- 3-[1-(Hydroxymethyl)-3,3-dimethylcyclobutyl]-1-methylpyrrolidin-3-ol2171940-48-8C12H23NO2
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