Murcko scaffold
3-Cyclobutylpyrrolidine scaffold
102 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 9
- Chemicals
- 102
- With full pages
- 4
Scaffold SMILES
C1CC(C2CCNC2)C1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 49 to 96 of 102 chemicals
![3-[1-(Hydroxymethyl)cyclobutyl]-1-methylpyrrolidin-3-ol chemical structure, C10H19NO2, CAS 2171835-71-3](/s/CIYNQJOWLJQTMZ-UHFFFAOYSA-N.svg)
3-[1-(Hydroxymethyl)cyclobutyl]-1-methylpyrrolidin-3-ol
CAS 2171835-71-3C10H19NO2
![1-[(tert-Butoxy)carbonyl]-3-(1-hydroxycyclobutyl)pyrrolidine-3-carboxylic acid chemical structure, C14H23NO5, CAS 2171836-16-9](/s/HYYPPWLEDVKEFC-UHFFFAOYSA-N.svg)
1-[(tert-Butoxy)carbonyl]-3-(1-hydroxycyclobutyl)pyrrolidine-3-carboxylic acid
CAS 2171836-16-9C14H23NO5
![tert-Butyl 3-hydroxy-3-[1-(hydroxymethyl)-3,3-dimethylcyclobutyl]pyrrolidine-1-carboxylate chemical structure, C16H29NO4, CAS 2172518-97-5](/s/NTJQSIUUWZCTQC-UHFFFAOYSA-N.svg)
tert-Butyl 3-hydroxy-3-[1-(hydroxymethyl)-3,3-dimethylcyclobutyl]pyrrolidine-1-carboxylate
CAS 2172518-97-5C16H29NO4
tert-Butyl 3-amino-3-(1-hydroxycyclobutyl)pyrrolidine-1-carboxylate
CAS 2171646-52-7C13H24N2O3
![3-[3,3-Difluoro-1-(hydroxymethyl)cyclobutyl]-1-methylpyrrolidin-3-ol chemical structure, C10H17F2NO2, CAS 2172554-85-5](/s/NBRDHATXGVHFJX-UHFFFAOYSA-N.svg)
3-[3,3-Difluoro-1-(hydroxymethyl)cyclobutyl]-1-methylpyrrolidin-3-ol
CAS 2172554-85-5C10H17F2NO2
3-(1-Amino-3-methoxycyclobutyl)-1-methylpyrrolidin-3-ol
CAS 2171647-88-2C10H20N2O2
![3-[1-(Hydroxymethyl)-3-methoxycyclobutyl]-1-methylpyrrolidin-3-ol chemical structure, C11H21NO3, CAS 2172581-16-5](/s/NXNPXEVCTFNPFB-UHFFFAOYSA-N.svg)
3-[1-(Hydroxymethyl)-3-methoxycyclobutyl]-1-methylpyrrolidin-3-ol
CAS 2172581-16-5C11H21NO3
Ethyl 1-(3-hydroxy-1-methylpyrrolidin-3-yl)cyclobutane-1-carboxylate
CAS 2172462-36-9C12H21NO3
![1-{1-[(tert-Butoxy)carbonyl]-3-hydroxypyrrolidin-3-yl}-3,3-difluorocyclobutane-1-carboxylic acid chemical structure, C14H21F2NO5, CAS 2171918-00-4](/s/YBQMAKXOSQIPMN-UHFFFAOYSA-N.svg)
1-{1-[(tert-Butoxy)carbonyl]-3-hydroxypyrrolidin-3-yl}-3,3-difluorocyclobutane-1-carboxylic acid
CAS 2171918-00-4C14H21F2NO5
tert-Butyl 3-(1-amino-3-methoxycyclobutyl)-3-hydroxypyrrolidine-1-carboxylate
CAS 2171764-45-5C14H26N2O4
tert-Butyl 3-hydroxy-3-(1-(methoxycarbonyl)cyclobutyl)pyrrolidine-1-carboxylate
CAS 2386251-98-3C15H25NO5
tert-Butyl 3-(1-amino-3,3-dimethylcyclobutyl)-3-hydroxypyrrolidine-1-carboxylate
CAS 2171759-40-1C15H28N2O3
3-(1-Amino-3,3-difluorocyclobutyl)-1-methylpyrrolidin-3-ol
CAS 2171702-85-3C9H16F2N2O
tert-Butyl 3-(1-aminocyclobutyl)-3-hydroxypyrrolidine-1-carboxylate
CAS 2171643-16-4C13H24N2O3
3-(1-Aminocyclobutyl)-1-methylpyrrolidin-3-ol
CAS 2171763-72-5C9H18N2O
Methyl 1-(3-hydroxy-1-methylpyrrolidin-3-yl)-3,3-dimethylcyclobutane-1-carboxylate
CAS 2171840-79-0C13H23NO3
rac-tert-Butyl (3R,4S)-3-cyclobutyl-4-hydroxypyrrolidine-1-carboxylate
CAS 2227807-29-4C13H23NO3
4-(3,3-Difluorocyclobutyl)pyrrolidine-3-carboxylic acid
CAS 2169128-83-8C9H13F2NO2
![1-{1-[(tert-Butoxy)carbonyl]-3-hydroxypyrrolidin-3-yl}-3,3-dimethylcyclobutane-1-carboxylic acid chemical structure, C16H27NO5, CAS 2172084-29-4](/s/VPQJCQMFHCPSCD-UHFFFAOYSA-N.svg)
1-{1-[(tert-Butoxy)carbonyl]-3-hydroxypyrrolidin-3-yl}-3,3-dimethylcyclobutane-1-carboxylic acid
CAS 2172084-29-4C16H27NO5
1-(3-Hydroxy-1-methylpyrrolidin-3-yl)-3-methoxycyclobutane-1-carboxylic acid
CAS 2172528-03-7C11H19NO4
tert-Butyl 3-cyclobutyl-4-hydroxypyrrolidine-1-carboxylate
CAS 2169588-15-0C13H23NO3
Ethyl 3-cyclobutylpyrrolidine-3-carboxylate
CAS 2117600-86-7C11H19NO2
tert-Butyl 3-cyclobutylpyrrolidine-3-carboxylate
CAS 2353133-04-5C13H23NO2
1-(3-Hydroxypyrrolidin-3-yl)cyclobutane-1-carboxylic acid
CAS 2166712-66-7C9H15NO3
- Ethyl 1-(3-hydroxypyrrolidin-3-yl)cyclobutane-1-carboxylate2580211-56-7C11H19NO3
- tert-Butyl 1-(3-hydroxypyrrolidin-3-yl)cyclobutane-1-carboxylate2639438-06-3C13H23NO3
- 1-{3-Hydroxy-1-[(prop-2-en-1-yloxy)carbonyl]pyrrolidin-3-yl}cyclobutane-1-carboxylic acid2680728-03-2C13H19NO5
- 3-Cyclobutyl-1-[(prop-2-en-1-yloxy)carbonyl]pyrrolidine-3-carboxylic acid2680828-00-4C13H19NO4
- 1-Acetyl-3-cyclobutylpyrrolidine-3-carboxylic acid2680781-97-7C11H17NO3
- 3-(Pyrrolidin-3-yl)cyclobutan-1-amine2680854-59-3C8H16N2
- 3-Cyclobutyl-1-(2,2,2-trifluoroacetyl)pyrrolidine-3-carboxylic acid2680719-19-9C11H14F3NO3
- 1-[3-Hydroxy-1-(2,2,2-trifluoroacetyl)pyrrolidin-3-yl]cyclobutane-1-carboxylic acid2680808-18-6C11H14F3NO4
- 1-(1-Acetyl-3-hydroxypyrrolidin-3-yl)cyclobutane-1-carboxylic acid2680822-83-5C11H17NO4
- rac-(3R,4S)-4-Cyclobutylpyrrolidin-3-ol hydrochloride, trans2694056-94-3C8H16ClNO
- rac-(2R,3R)-3-Cyclobutyl-1-[(prop-2-en-1-yloxy)carbonyl]pyrrolidine-2-carboxylic acid2763947-67-5C13H19NO4
- rac-tert-Butyl (3R,4R)-4-[(1r,3S)-3-hydroxycyclobutyl]pyrrolidine-3-carboxylate2763924-76-9C13H23NO3
- rac-Ethyl (3R,4R)-4-[(1r,3S)-3-hydroxycyclobutyl]pyrrolidine-3-carboxylate2763924-80-5C11H19NO3
- rac-(2R,3R)-1-Acetyl-3-cyclobutylpyrrolidine-2-carboxylic acid2763965-17-7C11H17NO3
- rac-(3R,4R)-4-[(1r,3S)-3-Hydroxycyclobutyl]-1-(2,2,2-trifluoroacetyl)pyrrolidine-3-carboxylic acid2764000-24-8C11H14F3NO4
- rac-Methyl (3R,4R)-4-[(1r,3S)-3-hydroxycyclobutyl]pyrrolidine-3-carboxylate2764014-60-8C10H17NO3
- rac-(3R,4R)-4-[(1r,3S)-3-Hydroxycyclobutyl]pyrrolidine-3-carboxylic acid2763903-08-6C9H15NO3
- 1-Acetyl-3-cyclobutylpyrrolidine-2-carboxylic acid2913397-62-1C11H17NO3
- Ethyl 3-cyclobutylpyrrolidine-2-carboxylate2112128-06-8C11H19NO2
- tert-Butyl 3-cyclobutylpyrrolidine-2-carboxylate2913397-51-8C13H23NO2
- 3-Cyclobutyl-1-(2,2,2-trifluoroacetyl)pyrrolidine-2-carboxylic acid2913401-90-6C11H14F3NO3
- 3-Cyclobutyl-1-[(prop-2-en-1-yloxy)carbonyl]pyrrolidine-2-carboxylic acid2913401-85-9C13H19NO4
- rac-(3R,4R)-4-Cyclobutylpyrrolidin-3-amine2138252-88-5C8H16N2
- rac-(3R,4R)-1-Acetyl-4-[(1s,3S)-3-hydroxycyclobutyl]pyrrolidine-3-carboxylic acid2763993-03-7C11H17NO4
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