Murcko scaffold
4H,5H-Thieno(3,2-c)pyridin-4-one scaffold
68 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 10
- Chemicals
- 68
- With full pages
- 6
Scaffold SMILES
O=c1[nH]ccc2sccc12
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
![Murcko scaffold O=c1[nH]ccc2sccc12](/scaffold/DUPNPBCUJHMSFZ-UHFFFAOYSA-N/structure.svg)
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 68 chemicals
![7-Bromo-4H,5H-thieno[3,2-c]pyridin-4-one chemical structure, C7H4BrNOS, CAS 29079-94-5](/s/IFGFCNNLXIUQIV-UHFFFAOYSA-N.svg)
7-Bromo-4H,5H-thieno[3,2-c]pyridin-4-one
CAS 29079-94-5C7H4BrNOS
4H,5H-Thieno(3,2-c)pyridin-4-one
CAS 27685-92-3C7H5NOS
![4-Oxo-4,5-dihydrothieno[3,2-c]pyridine-6-carboxylic acid chemical structure, C8H5NO3S, CAS 60249-02-7](/s/LTUVSXWFSWZPLS-UHFFFAOYSA-N.svg)
4-Oxo-4,5-dihydrothieno[3,2-c]pyridine-6-carboxylic acid
CAS 60249-02-7C8H5NO3S
![3-Methyl-5H-thieno[3,2-c]pyridin-4-one chemical structure, C8H7NOS, CAS 690635-71-3](/s/YCBCHKDACLRYNZ-UHFFFAOYSA-N.svg)
3-Methyl-5H-thieno[3,2-c]pyridin-4-one
CAS 690635-71-3C8H7NOS
![Ethyl 3-methyl-4-oxo-4,5-dihydrothieno[3,2-c]pyridine-7-carboxylate chemical structure, C11H11NO3S, CAS 869543-46-4](/s/ZQIKCKYDCDCDJE-UHFFFAOYSA-N.svg)
Ethyl 3-methyl-4-oxo-4,5-dihydrothieno[3,2-c]pyridine-7-carboxylate
CAS 869543-46-4C11H11NO3S
![7-Iodo-3-methyl-5H-thieno[3,2-c]pyridin-4-one chemical structure, C8H6INOS, CAS 869543-45-3](/s/JADBBBSLRXQXFF-UHFFFAOYSA-N.svg)
7-Iodo-3-methyl-5H-thieno[3,2-c]pyridin-4-one
CAS 869543-45-3C8H6INOS
![2-Bromothieno[3,2-c]pyridin-4(5H)-one chemical structure, C7H4BrNOS, CAS 28948-60-9](/s/ZDUWCUXIWRAXLF-UHFFFAOYSA-N.svg)
2-Bromothieno[3,2-c]pyridin-4(5H)-one
CAS 28948-60-9C7H4BrNOS
![7-Chloro-4H,5H-thieno[3,2-c]pyridin-4-one chemical structure, C7H4ClNOS, CAS 29079-93-4](/s/UXAIBZJDLXCTTM-UHFFFAOYSA-N.svg)
7-Chloro-4H,5H-thieno[3,2-c]pyridin-4-one
CAS 29079-93-4C7H4ClNOS
![2-Methylthieno[3,2-c]pyridin-4(5H)-one chemical structure, C8H7NOS, CAS 59207-23-7](/s/CZZYGMSEVJJFRE-UHFFFAOYSA-N.svg)
2-Methylthieno[3,2-c]pyridin-4(5H)-one
CAS 59207-23-7C8H7NOS
![2-Bromo-3-methylthieno[3,2-c]pyridin-4(5H)-one chemical structure, C8H6BrNOS, CAS 690635-73-5](/s/GYXMWPUFAAQXIF-UHFFFAOYSA-N.svg)
2-Bromo-3-methylthieno[3,2-c]pyridin-4(5H)-one
CAS 690635-73-5C8H6BrNOS
![2-Bromo-4-oxo-4,5-dihydrothieno[3,2-c]pyridine-7-carbonitrile chemical structure, C8H3BrN2OS, CAS 55040-43-2](/s/FIAFOJCIZMGXIV-UHFFFAOYSA-N.svg)
2-Bromo-4-oxo-4,5-dihydrothieno[3,2-c]pyridine-7-carbonitrile
CAS 55040-43-2C8H3BrN2OS
![2-Iodo-4-oxo-4,5-dihydro-thieno[3,2-c]pyridine-7-carbonitrile chemical structure, C8H3IN2OS, CAS 690635-51-9](/s/KPKREZQBHOEYOV-UHFFFAOYSA-N.svg)
2-Iodo-4-oxo-4,5-dihydro-thieno[3,2-c]pyridine-7-carbonitrile
CAS 690635-51-9C8H3IN2OS
![4-Oxo-4,5-dihydrothieno[3,2-c]pyridine-7-carbonitrile chemical structure, C8H4N2OS, CAS 55040-34-1](/s/ZZPNWIRCTPUMKN-UHFFFAOYSA-N.svg)
4-Oxo-4,5-dihydrothieno[3,2-c]pyridine-7-carbonitrile
CAS 55040-34-1C8H4N2OS
![3-Bromo-2-methyl-7-nitrothieno[3,2-c]pyridin-4(5H)-one chemical structure, C8H5BrN2O3S, CAS 832694-76-5](/s/UWIYXHYAFVRXAK-UHFFFAOYSA-N.svg)
3-Bromo-2-methyl-7-nitrothieno[3,2-c]pyridin-4(5H)-one
CAS 832694-76-5C8H5BrN2O3S
![3-Bromo-2-methylthieno[3,2-c]pyridin-4(5H)-one chemical structure, C8H6BrNOS, CAS 832694-72-1](/s/INLYQRYZXCQUAG-UHFFFAOYSA-N.svg)
3-Bromo-2-methylthieno[3,2-c]pyridin-4(5H)-one
CAS 832694-72-1C8H6BrNOS
![3-Bromo-7-methylthieno[3,2-c]pyridin-4(5H)-one chemical structure, C8H6BrNOS, CAS 832697-56-0](/s/AGIMSZPQFJLZNO-UHFFFAOYSA-N.svg)
3-Bromo-7-methylthieno[3,2-c]pyridin-4(5H)-one
CAS 832697-56-0C8H6BrNOS
![3-Bromothieno[3,2-c]pyridin-4(5H)-one chemical structure, C7H4BrNOS, CAS 799293-83-7](/s/AMWQWPCIUPRUFH-UHFFFAOYSA-N.svg)
3-Bromothieno[3,2-c]pyridin-4(5H)-one
CAS 799293-83-7C7H4BrNOS
![(2-Methyl-4-oxothieno[3,2-c]pyridin-5(4H)-yl)acetic acid chemical structure, C10H9NO3S, CAS 1172052-56-0](/s/AVMUDVBXDJIRPV-UHFFFAOYSA-N.svg)
(2-Methyl-4-oxothieno[3,2-c]pyridin-5(4H)-yl)acetic acid
CAS 1172052-56-0C10H9NO3S
![2-(4-Oxothieno[3,2-c]pyridin-5(4H)-yl)propanoic acid chemical structure, C10H9NO3S, CAS 118376-65-1](/s/PAKHWZXTPKJKGM-UHFFFAOYSA-N.svg)
2-(4-Oxothieno[3,2-c]pyridin-5(4H)-yl)propanoic acid
CAS 118376-65-1C10H9NO3S
2-(4-Oxo-4H,5H-thieno(3,2-c)pyridin-5-yl)acetic acid
CAS 1243101-05-4C9H7NO3S
![5-Methylthieno[3,2-C]pyridin-4(5H)-one chemical structure, C8H7NOS, CAS 55040-38-5](/s/AOPCBMZGIVZTBZ-UHFFFAOYSA-N.svg)
5-Methylthieno[3,2-C]pyridin-4(5H)-one
CAS 55040-38-5C8H7NOS
![7-Iodothieno[3,2-c]pyridin-4-ol chemical structure, C7H4INOS, CAS 1203579-68-3](/s/CXCZKVRCUJAGRH-UHFFFAOYSA-N.svg)
7-Iodothieno[3,2-c]pyridin-4-ol
CAS 1203579-68-3C7H4INOS
![3-Bromo-7-iodothieno[3,2-c]pyridin-4(5H)-one chemical structure, C7H3BrINOS, CAS 799293-88-2](/s/LWSKXKRUNCZEFY-UHFFFAOYSA-N.svg)
3-Bromo-7-iodothieno[3,2-c]pyridin-4(5H)-one
CAS 799293-88-2C7H3BrINOS
![Methyl 4-hydroxythieno[3,2-c]pyridine-7-carboxylate chemical structure, C9H7NO3S, CAS 1360929-34-5](/s/ZHPGTQXSUVAHIB-UHFFFAOYSA-N.svg)
Methyl 4-hydroxythieno[3,2-c]pyridine-7-carboxylate
CAS 1360929-34-5C9H7NO3S
- 2-Ethyl-4H,5H-thieno[3,2-c]pyridin-4-one502649-36-7C9H9NOS
- 2-Bromo-7-(trifluoromethyl)thieno[3,2-c]pyridin-4(5H)-one1956326-86-5C8H3BrF3NOS
- 7-(Trifluoromethyl)thieno[3,2-c]pyridin-4(5H)-one1936331-21-3C8H4F3NOS
- 2,3-Dibromo-5H-thieno[3,2-c]pyridin-4-one690635-74-6C7H3Br2NOS
- 4-Hydroxythieno[3,2-c]pyridine-7-carboxylic acid55040-46-5C8H5NO3S
- 3-Bromo-5-methylthieno[3,2-c]pyridin-4(5H)-one1410974-67-2C8H6BrNOS
- 2-Hydroxy-2-methyl-3-{4-oxo-4H,5H-thieno[3,2-c]pyridin-5-yl}propanoic acid1708229-12-2C11H11NO4S
- 7-Bromo-5-methyl-4-oxo-4,5-dihydrothieno[3,2-c]pyridine-2-carbaldehyde1610520-29-0C9H6BrNO2S
- 4-Oxo-4,5-dihydrothieno[3,2-c]pyridine-2-carbaldehyde1610520-27-8C8H5NO2S
- 7-Bromo-2-(hydroxymethyl)-5-methylthieno[3,2-c]pyridin-4-one1610520-62-1C9H8BrNO2S
- 7-Bromo-4-oxo-4,5-dihydrothieno[3,2-c]pyridine-2-carbaldehyde1610520-28-9C8H4BrNO2S
- 7-Bromo-2-(bromomethyl)-5-methylthieno[3,2-c]pyridin-4-one1610520-70-1C9H7Br2NOS
- 7-Bromo-5-methyl-2-(methylaminomethyl)thieno[3,2-c]pyridin-4-one1610520-53-0C10H11BrN2OS
- 7-Bromo-5-ethyl-4-oxo-4,5-dihydrothieno[3,2-c]pyridine-2-carbaldehyde1610520-49-4C10H8BrNO2S
- 4-Oxo-4,5-Dihydro-thieno[3,2-c]pyridine-2-carboxylic acid methyl ester1360965-52-1C9H7NO3S
- tert-Butyl N-[2-[(7-bromo-5-methyl-4-oxothieno[3,2-c]pyridin-2-yl)methylamino]ethyl]carbamate1610520-63-2C16H22BrN3O3S
- 3-Methyl-4-oxo-4H,5H-thieno[3,2-c]pyridine-2-carboxylic acid1360902-19-7C9H7NO3S
- 7-(Dimethylamino)-5H-thieno[3,2-c]pyridin-4-one55040-30-7C9H10N2OS
- 7-Methylsulfanyl-5H-thieno[3,2-c]pyridin-4-one55040-32-9C8H7NOS2
- 7-Bromo-5-ethyl-4-oxo-4,5-dihydrothieno[3,2-c]pyridine-2-carbonitrile1714146-63-0C10H7BrN2OS
- 2,7-Dibromo-5H-thieno[3,2-c]pyridin-4-one55040-36-3C7H3Br2NOS
- 4-Oxo-5H-thieno[3,2-c]pyridine-2,7-dicarbonitrile55040-45-4C9H3N3OS
- 7-Bromo-5-methyl-4-oxo-4H,5H-thieno[3,2-c]pyridine-2-carbonitrile1714146-49-2C9H5BrN2OS
- 4-Oxo-4,5-dihydrothieno[3,2-c]pyridine-2-carboxylic acid1360929-58-3C8H5NO3S
Related scaffolds
Same ring framework with different atoms or bond orders
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